Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Aurel Perren"'
Autor:
Simon L. April-Monn, Philipp Kirchner, Katharina Detjen, Konstantin Bräutigam, Mafalda A. Trippel, Tobias Grob, Cyril Statzer, Renaud S. Maire, Attila Kollàr, Aziz Chouchane, Catarina A. Kunze, David Horst, Martin C. Sadowski, Jörg Schrader, Ilaria Marinoni, Bertram Wiedenmann, Aurel Perren
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract There are no therapeutic predictive biomarkers or representative preclinical models for high-grade gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN), a highly aggressive, fatal, and heterogeneous malignancy. We established patient-de
Externí odkaz:
https://doaj.org/article/4501b816ee864b8c8c471a5b031bef76
Autor:
Kiarash Tajbakhsh, Antonia Neels, Elena Fadeeva, Jakob C. Larsson, Olga Stanowska, Aurel Perren, Robert Zboray
Publikováno v:
IEEE Access, Vol 12, Pp 78304-78316 (2024)
Advances in laboratory-based X-ray computed tomography (CT) have enabled X-ray 3D virtual histology. This method shows a great potential as a complementary technique to conventional 2D histology where extensive volumetric sampling is necessary. While
Externí odkaz:
https://doaj.org/article/5216406a9283469287888d6af6f53930
Autor:
Paulo Sampaio, Maria Lopez-Antuña, Federico Storni, Jonatan Wicht, Greta Sökeland, Martin Wartenberg, Pablo Márquez-Neila, Daniel Candinas, Brice-Olivier Demory, Aurel Perren, Raphael Sznitman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Polarimetry is an optical characterization technique capable of analyzing the polarization state of light reflected by materials and biological samples. In this study, we investigate the potential of Müller matrix polarimetry (MMP) to analy
Externí odkaz:
https://doaj.org/article/eaed0988715140fa9c1d1e35bf32b0a2
Autor:
Magdalena Skoworonska, Annika Blank, Irene Centeno, Caroline Hammer, Aurel Perren, Inti Zlobec, Tilman T Rau
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 2, Pp 137-148 (2023)
Abstract The standardized preanalytical code (SPREC) aggregates warm ischemia (WIT), cold ischemia (CIT), and fixation times (FIT) in a precise format. Despite its growing importance underpinned by the European in vitro diagnostics regulation or broa
Externí odkaz:
https://doaj.org/article/b8e573fe261f4c1ea76735c57e61326c
Autor:
Patcharamon Seubnooch, Matteo Montani, Sofia Tsouka, Emmanuelle Claude, Umara Rafiqi, Aurel Perren, Jean-Francois Dufour, Mojgan Masoodi
Publikováno v:
JHEP Reports, Vol 5, Iss 6, Pp 100725- (2023)
Background & Aims: Lipid metabolism plays an important role in liver pathophysiology. The liver lobule asymmetrically distributes oxygen and nutrition, resulting in heterogeneous metabolic functions. Periportal and pericentral hepatocytes have differ
Externí odkaz:
https://doaj.org/article/4cb61df4e1fa4c48b371b0f15eb456ba
Autor:
Sebastian Stenman, Sylvain Bétrisey, Paula Vainio, Jutta Huvila, Mikael Lundin, Nina Linder, Anja Schmitt, Aurel Perren, Matthias S. Dettmer, Caj Haglund, Johanna Arola, Johan Lundin
Publikováno v:
Journal of Pathology Informatics, Vol 15, Iss , Pp 100366- (2024)
The tall cell subtype (TC-PTC) is an aggressive subtype of papillary thyroid carcinoma (PTC). The TC-PTC is defined as a PTC comprising at least 30% epithelial cells that are three times as tall as they are wide. In practice, this definition is diffi
Externí odkaz:
https://doaj.org/article/53effa25388d40b68b6d631c065bffdb
Autor:
Tincy Simon, Pamela Riemer, Armin Jarosch, Katharina Detjen, Annunziata Di Domenico, Felix Bormann, Andrea Menne, Slim Khouja, Nanna Monjé, Liam H. Childs, Dido Lenze, Ulf Leser, Florian Rossner, Markus Morkel, Nils Blüthgen, Marianne Pavel, David Horst, David Capper, Ilaria Marinoni, Aurel Perren, Soulafa Mamlouk, Christine Sers
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-14 (2022)
Abstract Background Pancreatic neuroendocrine neoplasms (PanNENs) fall into two subclasses: the well-differentiated, low- to high-grade pancreatic neuroendocrine tumors (PanNETs), and the poorly-differentiated, high-grade pancreatic neuroendocrine ca
Externí odkaz:
https://doaj.org/article/2f176528de284862b6e90f388629cecf
Autor:
Annunziata Di Domenico, Christodoulos P. Pipinikas, Renaud S. Maire, Konstantin Bräutigam, Cedric Simillion, Matthias S. Dettmer, Erik Vassella, Chrissie Thirlwell, Aurel Perren, Ilaria Marinoni
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Di Domenico et al., provide a comprehensive assessment of DNA methylation in a large cohort of pancreatic neuroendocrine tumors. This work provides new insights into the epigenetic heterogeneity of the disease and cellular basis.
Externí odkaz:
https://doaj.org/article/a3f12048273d452cbac17af8d0e13581
Autor:
Sebastian Gulde, Alessia Foscarini, Simon L. April-Monn, Edoardo Genio, Alessandro Marangelo, Swapna Satam, Daniel Helbling, Massimo Falconi, Rodrigo A. Toledo, Jörg Schrader, Aurel Perren, Ilaria Marinoni, Natalia S. Pellegata
Publikováno v:
Cancers, Vol 14, Iss 22, p 5481 (2022)
Pancreatic neuroendocrine neoplasms (PanNENs) are the second most common malignancy of the pancreas. Surgery remains the only curative treatment for localized disease. For patients with inoperable advanced or metastatic disease, few targeted therapie
Externí odkaz:
https://doaj.org/article/6474ac408bf64061b80fe3e402dc086a
Autor:
Reuben S. E. Young, Britt S. R. Claes, Andrew P. Bowman, Elizabeth D. Williams, Benjamin Shepherd, Aurel Perren, Berwyck L. J. Poad, Shane R. Ellis, Ron M. A. Heeren, Martin C. Sadowski, Stephen J. Blanksby
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Prostate cancer is the fourth most common cancer worldwide with definitive diagnosis reliant on biopsy and human-graded histopathology. As with other pathologies, grading based on classical haematoxylin and eosin (H&E) staining of formalin fixed para
Externí odkaz:
https://doaj.org/article/1230b39ffff14ef29ef2632067fc8981