Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Aurel, Holzschuh"'
Autor:
Bakar S. Fakih, Aurel Holzschuh, Amanda Ross, Logan Stuck, Ramadhan Abdul, Abdul-Wahid H. Al-Mafazy, Imani Irema, Abdallah Mbena, Sumaiyya G. Thawer, Shija J. Shija, Safia M. Aliy, Abdullah Ali, Günther Fink, Joshua Yukich, Manuel W. Hetzel
Publikováno v:
Infectious Diseases of Poverty, Vol 12, Iss 1, Pp 1-11 (2023)
Abstract Background Zanzibar has made substantial progress in malaria control with vector control, improved diagnosis, and artemisinin-based combination therapy. Parasite prevalence in the population has remained around 1% but imported infections fro
Externí odkaz:
https://doaj.org/article/59072d382c2f4b2cbc86af1e406f7ede
Autor:
Aurel Holzschuh, Anita Lerch, Inna Gerlovina, Bakar S. Fakih, Abdul-wahid H. Al-mafazy, Erik J. Reaves, Abdullah Ali, Faiza Abbas, Mohamed Haji Ali, Mohamed Ali Ali, Manuel W. Hetzel, Joshua Yukich, Cristian Koepfli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Zanzibar has made significant progress toward malaria elimination, but recent stagnation requires novel approaches. We developed a highly multiplexed droplet digital PCR (ddPCR)-based amplicon sequencing method targeting 35 microhaplotypes a
Externí odkaz:
https://doaj.org/article/e119a44ae3ca43a381f91fd4b07975f6
Autor:
Aurel Holzschuh, Anita Lerch, Bakar S Fakih, Safia Mohammed Aliy, Mohamed Haji Ali, Mohamed Ali Ali, Daniel J Bruzzese, Joshua Yukich, Manuel W Hetzel, Cristian Koepfli
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 2, p e0002743 (2024)
Genomic epidemiology holds promise for malaria control and elimination efforts, for example by informing on Plasmodium falciparum genetic diversity and prevalence of mutations conferring anti-malarial drug resistance. Limited sequencing infrastructur
Externí odkaz:
https://doaj.org/article/c9dd18a9af1b4bb3bca41b475656f009
Autor:
Aurel Holzschuh, Cristian Koepfli
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background Molecular and genomic surveillance is becoming increasingly used to track malaria control and elimination efforts. Blood samples can be collected as whole blood and stored at − 20 °C until DNA extraction, or as dried blood spot
Externí odkaz:
https://doaj.org/article/b74b605ec3d1470d92bf5caaee102868
Autor:
Aurel Holzschuh, Maria Gruenberg, Natalie E Hofmann, Rahel Wampfler, Benson Kiniboro, Leanne J Robinson, Ivo Mueller, Ingrid Felger, Michael T White
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 9, p e0010760 (2022)
BackgroundCo-infection of the four major species of human malaria parasite Plasmodium falciparum (Pf), P. vivax (Pv), P. malariae (Pm), and P. ovale sp. (Po) is regularly observed, but there is limited understanding of between-species interactions. I
Externí odkaz:
https://doaj.org/article/cb7ba1da20224a2f805c1d15eddb6829
Autor:
Claudia A Vera-Arias, Aurel Holzschuh, Colins O Oduma, Kingsley Badu, Mutala Abdul-Hakim, Joshua Yukich, Manuel W Hetzel, Bakar S Fakih, Abdullah Ali, Marcelo U Ferreira, Simone Ladeia-Andrade, Fabián E Sáenz, Yaw Afrane, Endalew Zemene, Delenasaw Yewhalaw, James W Kazura, Guiyun Yan, Cristian Koepfli
Publikováno v:
eLife, Vol 11 (2022)
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false-negative tests and are a threat for malaria control. A novel assay for mole
Externí odkaz:
https://doaj.org/article/6f54373be68449cb86b4efdc4a27f191
Autor:
Logan Stuck, Bakar S. Fakih, Abdul-wahid H. Al-mafazy, Natalie E. Hofmann, Aurel Holzschuh, Benjamin Grossenbacher, Adam Bennett, Chris Cotter, Erik Reaves, Abdullah Ali, Tina van der Horst, Ingrid Felger, Manuel W. Hetzel, Joshua Yukich
Publikováno v:
International Journal of Infectious Diseases, Vol 97, Iss , Pp 337-346 (2020)
Background: Reactive case detection (RCD) is a commonly used strategy for malaria surveillance and response in elimination settings. Many approaches to RCD assume detectable infections are clustered within and around homes of passively detected cases
Externí odkaz:
https://doaj.org/article/d8614fc2979848598f68231ff160347a
Autor:
Benjamin Grossenbacher, Aurel Holzschuh, Natalie E. Hofmann, Kali Abdullah Omar, Logan Stuck, Bakar Shariff Fakih, Abdullah Ali, Joshua Yukich, Manuel W. Hetzel, Ingrid Felger
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background Molecular detection of low-density Plasmodium falciparum infections is essential for surveillance studies conducted to inform malaria control strategies in close-to-elimination settings. Molecular monitoring of residual malaria in
Externí odkaz:
https://doaj.org/article/be468b5f0a4d45829a278bbc8f3fd25c
Autor:
David Niyukuri, Denis Sinzinkayo, Emma V Troth, Colins O Oduma, Mediatrice Barengayabo, Mireille Ndereyimana, Aurel Holzschuh, Claudia A Vera-Arias, Yilekal Gebre, Kingsley Badu, Joseph Nyandwi, Dismas Baza, Elizabeth Juma, Cristian Koepfli
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 7, p e0000828 (2022)
Rapid diagnostic tests (RDTs) are a key tool for the diagnosis of malaria infections among clinical and subclinical individuals. Low-density infections, and deletions of the P. falciparum hrp2/3 genes (encoding the HRP2 and HRP3 proteins detected by
Externí odkaz:
https://doaj.org/article/1c7c011f775148268d79d6da8ed0fa97
Autor:
Aurel Holzschuh, Anita Lerch, Inna Gerlovina, Bakar S. Fakih, Abdul-wahid H. Al-mafazy, Erik J. Reaves, Abdullah Ali, Faiza Abbas, Mohamed Haji Ali, Mohamed Ali Ali, Manuel W. Hetzel, Joshua Yukich, Cristian Koepfli
Over the past 15 years, Zanzibar has made great strides towards malaria elimination; yet progress has stalled. Parasite genetic data ofPlasmodium falciparummay inform strategies for malaria elimination by helping to identify contributory factors to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10c51306b01fe3e2a20c29fa1297698
https://doi.org/10.1101/2023.01.05.522832
https://doi.org/10.1101/2023.01.05.522832
