Výsledky vyhledávání - "Aura S Kamiguti"

Biological properties of the venom of the Papuan black snake (Pseudechis papuanus): presence of a phospholipase A2 platelet inhibitor

Autor: Mirko Zuzel, Gavin D. Laing, David A. Warrell, Aura S. Kamiguti, R.D.G. Theakston, G.M. Lowe

The whole venom of Pseudechis papuanus, in addition to its anticoagulant activity, powerfully inhibited platelet aggregation induced by ADP, adrenaline, collagen, ristocetin and thrombin. High levels of phospholipase A2 (PLA2) activity were detected.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6effa12226adf3ac502ebc8dcfc644
https://ora.ox.ac.uk/objects/uuid:cdf2c82d-218b-4194-89d1-44843e9064de

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Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities

Autor: Jay W. Fox, Leandra Watanabe, R. David G. Theakston, Raghuvir K. Arni, José María Gutiérrez, Aura S. Kamiguti, John D. Shannon, Richard H. Valente, Alexandra Rucavado, Alberto Alape-Girón

Publikováno v: Protein Science; Volumen 12, Número 10. 2003
Kérwá
Universidad de Costa Rica
instacron:UCR
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2014-02-26T17:16:52Z No. of bitstreams: 1 WOS000185425500016.pdf: 436693 bytes, checksum: 6e53e418baab576ea898d4d9383e0c12 (MD5) Made available in DSpace on 2014-02-26T17:16:52Z (GMT). N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb5b7d86ffab67bb8a1ad3860d7115b
https://doi.org/10.1110/ps.03102403

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Expression and Activity of NOX5 in the Circulating Malignant B Cells of Hairy Cell Leukemia

Autor: David Allsup, Lena Serrander, Joseph R. Slupsky, Mirko Zuzel, Ke Lin, Karl-Heinz Krause, John C. Cawley, Robert J. Harris, Aura S. Kamiguti

Publikováno v: Journal of Immunology, Vol. 175, No 12 (2005) pp. 8424-8430

Hairy cells (HCs) are mature malignant B cells that contain a number of constitutively active signaling molecules including GTP-bound Rac1, protein kinase C, and Src family kinases. Because Rac1 is a component of the reactive oxidant species (ROS)-ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3854984926dbda51dd56efeec76133
https://doi.org/10.4049/jimmunol.175.12.8424

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Characterization of a novel protein from Proatheris superciliaris venom: Proatherocytin, a 34-kDa platelet receptor PAR1 agonist

Autor: Rithwik Ramachandran, Gemma L.J. Fuller, Simon C. Wagstaff, Mark C. Wilkinson, Yotis A. Senis, Aura S. Kamiguti, Gavin D. Laing, Stephen P. Watson, R. David G. Theakston, Steven J. Compton

Publikováno v: Physiology and Pharmacology Publications

Many toxins from viperid venoms have been characterised as powerful activators of platelets. Here, the venom from the East African Lowland viper, Proatheris superciliaris, was investigated for its effect on platelets and the coagulation system. Whole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05922d7aa07c954f192eb328228ef598
https://doi.org/10.1016/j.toxicon.2005.06.011

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Platelets as targets of snake venom metalloproteinases

Autor: Aura S. Kamiguti

Publikováno v: Toxicon. 45:1041-1049

For centuries snake venoms have been known to interfere with haemostasis and this is now known basically due either to toxins activating/inhibiting clotting factors, having effects on blood vessels or interfering with platelet function. In this short

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c15ca516fe3ca0dbe5db07e3bcdb046
https://doi.org/10.1016/j.toxicon.2005.02.026

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Failure of chloramphenicol prophylaxis to reduce the frequency of abscess formation as a complication of envenoming by Bothrops snakes in Brazil: a double-blind randomized controlled trial

Autor: João Luiz Costa Cardoso, Sérgio de Andrade Nishioka, David A. Warrell, Hui Wen Fan, Ceila Maria Sant’Ana Malaque, Ida S. Sano-Martins, Miguel Tanús Jorge, Aura S. Kamiguti, Francisco Oscar de Siqueira França, R.D.G. Theakston, L A Ribeiro

Publikováno v: Transactions of the Royal Society of Tropical Medicine and Hygiene. 98:529-534

Bites by many species of venomous snake may result in local necrosis at, or extending from, the site of the bite. The use of prophylactic antibiotics to prevent infection as a complication of local necrotic envenoming is controversial. A double-blind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a98fd623bc265ff38086fa8fdb325e
https://doi.org/10.1016/j.trstmh.2003.12.009

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The role of matrix metalloproteinase 9 in the pathogenesis of chronic lymphocytic leukaemia

Autor: Kathleen J. Till, Hai Juan Chen, Mirko Zuzel, John C. Cawley, Robert J. Harris, Ke Lin, Edwin S. Lee, Mark A. Glenn, Aura S. Kamiguti

Publikováno v: British Journal of Haematology. 125:128-140

Summary Matrix metalloproteinases (MMPs) are important for the pathogenesis and progression of different tumours. MMPs-2 and -9 are the principal MMPs produced by lymphocytes; these enzymes can degrade a number of matrix proteins but are the two main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cd68f2c21419103de602e563b2c0c1a
https://doi.org/10.1111/j.1365-2141.2004.04877.x

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Characterization of ‘basparin A,’ a prothrombin-activating metalloproteinase, from the venom of the snake Bothrops asper that inhibits platelet aggregation and induces defibrination and thrombosis

Autor: R. David G. Theakston, Gilbert D. Loría, Alexandra Rucavado, Jay W. Fox, Aura S. Kamiguti, Alberto Alape, José María Gutiérrez

Publikováno v: Archives of Biochemistry and Biophysics; Volumen 418, Número 1. 2003
Kérwá
Universidad de Costa Rica
instacron:UCR

A prothrombin activator, named ‘basparin A,’ was isolated from the venom of the crotaline snake Bothrops asper, the species responsible for the majority of snakebite cases in Central America. It is an acidic (pI 5.4), 70 kDa, single chain P-III m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56feb693b5d5267ffb444c8884334fe1
https://doi.org/10.1016/s0003-9861(03)00385-0

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Use of microarrays for investigating the subtoxic effects of snake venoms: insights into venom-induced apoptosis in human umbilical vein endothelial cells

Autor: Paul Gallagher, Yongde Bao, R. David G. Theakston, Aura S. Kamiguti, Jay W. Fox, Solange M.T. Serrano

Publikováno v: Toxicon. 41:429-440

The pathological effects of only a small percentage of the total number of protein components of snake venoms are well documented, yet this knowledge has led to a general understanding of the physiological consequences of snake venom poisoning. The a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4de96c1072188fb62abd4b7a8f84d8
https://doi.org/10.1016/s0041-0101(02)00359-8

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