Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Aura Muntasell"'
Autor:
Sara Santana-Hernández, Jesús Suarez-Olmos, Sonia Servitja, Pau Berenguer-Molins, Marcel Costa-Garcia, Laura Comerma, Anna Rea, Julia Perera-Bel, Silvia Menendez, Oriol Arpí, Begoña Bermejo, María Teresa Martínez, Juan Miguel Cejalvo, Iñaki Comino-Méndez, Javier Pascual, Emilio Alba, Miguel López-Botet, Federico Rojo, Ana Rovira, Joan Albanell, Aura Muntasell
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The variability in responses to neoadjuvant treatment with anti-HER2 antibodies prompts to personalized clinical management and the development of innovative treatment strategies. Tumor-infiltrating Natural Killer (TI-NK) cells ca
Externí odkaz:
https://doaj.org/article/5bc22c2f73dc42618cc14ecab70aa357
Autor:
Elisenda Alari-Pahissa, Michelle Ataya, Ilias Moraitis, Miriam Campos-Ruiz, Mireia Altadill, Aura Muntasell, Anna Moles, Miguel López-Botet
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009868 (2021)
Epstein Barr virus (EBV) causes a highly prevalent and lifelong infection contributing to the development of some malignancies. In addition to the key role played by T cells in controlling this pathogen, NK cells mediate cytotoxicity and IFNγ produc
Externí odkaz:
https://doaj.org/article/37ba866f52fc4103820b1d791c8a62bf
Autor:
Elisa Cisneros, Manuela Moraru, Natalia Gómez-Lozano, Aura Muntasell, Miguel López-Botet, Carlos Vilches
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Inhibitory Killer-cell Immunoglobulin-like Receptors (KIR) specific for HLA class I molecules enable human natural killer cells to monitor altered antigen presentation in pathogen-infected and tumor cells. KIR genes display extensive copy-number vari
Externí odkaz:
https://doaj.org/article/e06a7268799144a7917e31e06f5d233c
Autor:
Maria C. Ochoa, Elisabeth Perez-Ruiz, Luna Minute, Carmen Oñate, Guiomar Perez, Inmaculada Rodriguez, Aintzane Zabaleta, Diego Alignani, Myriam Fernandez-Sendin, Ascension Lopez, Aura Muntasell, Miguel F. Sanmamed, Bruno Paiva, Miguel Lopez-Botet, Pedro Berraondo, Ignacio Melero
Publikováno v:
OncoImmunology, Vol 8, Iss 7 (2019)
Daratumumab is an anti-CD38 fully human IgG1 mAb approved for multiple myeloma treatment. One of the proposed mechanisms of action is the induction of antibody-dependent cellular cytotoxicity (ADCC) mediated by NK cells. NK cells acquire surface CD13
Externí odkaz:
https://doaj.org/article/469445f7b4c148028345cf1278b80df7
Autor:
Marcel Costa-García, Michelle Ataya, Manuela Moraru, Carlos Vilches, Miguel López-Botet, Aura Muntasell
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing infected cells as well as by regulating anti-viral T cell immunity. Infection by human cytomegalovirus (HCMV) promotes a persistent expansion of NKG2
Externí odkaz:
https://doaj.org/article/710d22039a3e42f7a9309d9c3b341d18
Autor:
Mariona Cabo, Rienk Offringa, Laurence Zitvogel, Guido Kroemer, Aura Muntasell, Lorenzo Galluzzi
Publikováno v:
OncoImmunology, Vol 6, Iss 12 (2017)
The goal of cancer immunotherapy is to establish new or boost pre-existing anticancer immune responses that eradicate malignant cells while generating immunological memory to prevent disease relapse. Over the past few years, immunomodulatory monoclon
Externí odkaz:
https://doaj.org/article/6cda4163a20b4208a982e6d3ad306694
Autor:
Aura Muntasell, Mariona Cabo, Sonia Servitja, Ignasi Tusquets, María Martínez-García, Ana Rovira, Federico Rojo, Joan Albanell, Miguel López-Botet
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Overexpression of the human epidermal growth factor receptor 2 (HER2) defines a subgroup of breast tumors with aggressive behavior. The addition of HER2-targeted antibodies (i.e., trastuzumab, pertuzumab) to chemotherapy significantly improves relaps
Externí odkaz:
https://doaj.org/article/05232de585a545e1b4b0e14b87019fea
Autor:
Aldi Pupuleku, Marcel Costa-García, Domènec Farré, Hartmut Hengel, Ana Angulo, Aura Muntasell, Miguel López-Botet
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Human cytomegalovirus (HCMV) infection promotes the differentiation and persistent expansion of a mature NK cell subset, which displays high surface levels of the activating CD94/NKG2C NK cell receptor, together with additional distinctive phenotypic
Externí odkaz:
https://doaj.org/article/213a719ebf8240cca85ecf72bbdaf4a2
Autor:
Diego Sanchez-Martinez, Pilar Lanuza, Natalia Gomez, Aura Muntasell, Elisa Cisneros Leralta, Manuela Moraru, Gemma Azaceta, Alberto Anel, Luis Martínez-Lostao, Martin Villalba, Luis Palomera, Carlos Vilches, Jose A García Marco, Julian Pardo
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Mutational status of TP53 together with expression of wild type (wt) IGHV represents the most widely accepted biomarkers, establishing a very poor prognosis in B-cell chronic lymphocytic leukemia (B-CLL) patients. Adoptive cell therapy using allogene
Externí odkaz:
https://doaj.org/article/39abf86fe4ec4145959151c4868b0b49
Autor:
Aura Muntasell, Miguel López-Botet, Ignacio Melero, Joan Albanell, Pedro Berraondo, Ana Rovira, Laura Comerma, Silvia Menéndez, Maria C. Ochoa, Manel Juan, Francesc Balaguer, Michelle Ataya, Roberto Lozano-Rodríguez, Anna Rea, Marcel Costa-Garcia, Sara Santana-Hernández, Mariona Cabo
Enhancing natural killer (NK) cell–based cancer immunotherapy by overcoming immunosuppression is an area of intensive research. Here, we have demonstrated that the anti-CD137 agonist urelumab can overcome TGFβ-mediated inhibition of human NK-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55eece933a417d140ac1db0cf999894f
https://doi.org/10.1158/2326-6066.c.6550737
https://doi.org/10.1158/2326-6066.c.6550737