Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Aura Enache"'
Autor:
Lindsey Mayes-Hopfinger, Aura Enache, Jian Xie, Chou-Long Huang, Robert Köchl, Victor L. J. Tybulewicz, Teresa Fernandes-Alnemri, Emad S. Alnemri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The serine/threonine kinase WNK1 is an inhibitor of chloride efflux. Here the authors show that this inhibition is a means of negatively regulating the activation of the NLRP3 inflammasome in macrophages, leading to reduced inflammatory responses.
Externí odkaz:
https://doaj.org/article/e7b7e958ca504bdc89a48c00f18c7b6c
Autor:
Emad S. Alnemri, Teresa Fernandes-Alnemri, Jian Xie, Victor L. J. Tybulewicz, Aura Enache, Robert Köchl, Lindsey Mayes-Hopfinger, Chou Long Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
The NLRP3 inflammasome mediates the production of proinflammatory cytokines and initiates inflammatory cell death. Although NLRP3 is essential for innate immunity, aberrant NLRP3 inflammasome activation contributes to a wide variety of inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f780841c38901b3d5be2b16ce4f2bd
https://doaj.org/article/e7b7e958ca504bdc89a48c00f18c7b6c
https://doaj.org/article/e7b7e958ca504bdc89a48c00f18c7b6c