Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Aurélien Lathuilière"'
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 10578-10600 (2015)
Ex vivo gene therapy using retrievable encapsulated cellular implants is an effective strategy for the local and/or chronic delivery of therapeutic proteins. In particular, it is considered an innovative approach to modulate the activity of the immun
Externí odkaz:
https://doaj.org/article/479fa0de89f64d058622da3d15beff1b
Publikováno v:
Nutrients, Vol 11, Iss 4, p 881 (2019)
Stroke is the second leading cause of death worldwide but also of disability. Stroke induces certain alterations of muscle metabolism associated with gross muscle atrophy and a decrease in muscle function, leading to sarcopenia. The vast majority of
Externí odkaz:
https://doaj.org/article/b4dd01a10ba44d18b48607aef933ab98
Autor:
Augusto J. Mendes, Federica Ribaldi, Aurelien Lathuiliere, Nicholas J. Ashton, Henrik Zetterberg, Marc Abramowicz, Max Scheffler, Frédéric Assal, Valentina Garibotto, Kaj Blennow, Giovanni B. Frisoni
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Plasma biomarkers of Alzheimer’s disease (AD) pathology, neurodegeneration, and neuroinflammation are ideally suited for secondary prevention programs in self-sufficient persons at-risk of dementia. Plasma biomarkers have been s
Externí odkaz:
https://doaj.org/article/0d2fed2960a540e5986c1c8a6adf24c2
Autor:
Simon Dujardin, Dudley K. Strickland, Allison L. Arai, Molly Migliorini, Mashhood Wani, B. T. Hyman, Joanna M. Cooper, Aurélien Lathuilière, Selen C. Muratoglu
The identification of the apoE receptor, LRP1, as an endocytic receptor for tau raises several questions about LRP1s’ role in tauopathies. Is internalized tau, like other LRP1 ligands, delivered to lysosomes for degradation? Does LRP1 internalize p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dcf8436a7f69e8019c2890b7cfc4ff3
https://doi.org/10.1101/2020.11.17.386581
https://doi.org/10.1101/2020.11.17.386581
Publikováno v:
Revue medicale suisse. 15(670)
Stroke is the most common acute neurological disease in the world. Approximately 16 000 strokes occur each year in Switzerland. In the older population, the stroke outcomes are related to high risk of malnutrition due to neurological deficits impacti
Autor:
Aurelien Lathuiliere, Youhwa Jo, Romain Perbet, Cameron Donahue, Caitlin Commins, Noé Quittot, Zhanyun Fan, Rachel E. Bennett, Bradley T. Hyman
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background The prion-like propagation of tau in neurodegenerative disorders implies that misfolded pathological tau can recruit the normal protein and template its aggregation. Here, we report the methods for the development of sensitive bio
Externí odkaz:
https://doaj.org/article/fc15df3efa934d16963e5ff8c35d1c47
Autor:
Judith A. Steen, Dinorah Jean-Gilles, Pieter Beerepoot, Naomi Klickstein, Bradley T. Hyman, Mark B. De Los Santos, Tarun V. Kamath, Renee Moore, Arthur Viode, Aurélien Lathuilière, Lori B. Chibnik, Matthew P. Frosch, Ryan C. Clark, Derek H. Oakley, Alberto Serrano-Pozo, Benjamin D. Moore, Fiona Elwood, Rudolph E. Tanzi, Diana L. Corjuc, Simon Dujardin, Analiese R. Fernandes, Matthew E. Kennedy, Patrick M. Dooley, Bianca T. Corjuc, Kristina Mullin, Caitlin Commins, Kevin Atchison
Publikováno v:
Nat Med
Nature medicine, Vol. 26, No 8 (2020) pp. 1256-1263
Nature medicine, Vol. 26, No 8 (2020) pp. 1256-1263
Alzheimer's disease (AD) causes unrelenting, progressive cognitive impairments, but its course is heterogeneous, with a broad range of rates of cognitive decline1. The spread of tau aggregates (neurofibrillary tangles) across the cerebral cortex para
Autor:
Lori B. Chibnik, Benjamin D. Moore, Arthur Viode, Fiona Elwood, Tarun V. Kamath, Renee Moore, Patrick M. Dooley, Derek H. Oakley, Dinorah Jean-Gilles, Pieter Beerepoot, Alberto Serrano-Pozo, Diana L. Corjuc, Naomi Klickstein, Bradley T. Hyman, Kevin Atchison, Mark B. De Los Santos, Matthew P. Frosch, Aurélien Lathuilière, Judith A. Steen, Kristina Mullin, Analiese R. Fernandes, Matthew E. Kennedy, Caitlin Commins, Rudolph E. Tanzi, Simon Dujardin, Ryan C. Clark, Bianca T. Corjuc
Publikováno v:
Nature Medicine. 27:356-356
Autor:
Mashhood Wani, Mary Migliorini, Dudley K. Strickland, Allison L. Arai, Bradley T. Hyman, Aurélien Lathuilière, Simon Dujardin, Selen C. Muratoglu, Joanna M. Cooper
Publikováno v:
Journal of Biological Chemistry
The Journal of Biological Chemistry
Journal of Biological Chemistry, Vol. 296 (2021) P. 100715
The Journal of Biological Chemistry
Journal of Biological Chemistry, Vol. 296 (2021) P. 100715
In Alzheimer's disease (AD), pathological forms of tau are transferred from cell to cell and "seed" aggregation of cytoplasmic tau. Phosphorylation of tau plays a key role in neurodegenerative tauopathies. In addition, apolipoprotein E (apoE), a majo
Autor:
Alberto Astolfo, Aurélien Lathuilière, Bernard L. Schneider, Marco Stampanoni, Vanessa Laversenne
Publikováno v:
Journal of Synchrotron Radiation
Journal of Synchrotron Radiation, 23 (3)
Journal of synchrotron radiation, Vol. 23, No Pt 3 (2016) pp. 813-819
Journal of Synchrotron Radiation, 23 (3)
Journal of synchrotron radiation, Vol. 23, No Pt 3 (2016) pp. 813-819
Amyloid beta accumulation into insoluble plaques (Aβp) is known to play a significant role in the pathological process in Alzheimer's disease (AD). The presence of Aβp is also one of the neuropathological hallmarks for the disease. AD final diagnos