Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aurélien J. C. Pommier"'
Autor:
Aurélien J C Pommier, Julie Dufour, Georges Alves, Emilie Viennois, Hugues De Boussac, Amalia Trousson, David H Volle, Françoise Caira, Pierre Val, Philippe Arnaud, Jean-Marc A Lobaccaro, Silvère Baron
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003483 (2013)
LXR (Liver X Receptors) act as "sensor" proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines. This study shows t
Externí odkaz:
https://doaj.org/article/5418f4c803af48caa6724ceb18958b56
Autor:
Laurent Guy, Emilie Viennois, Silvère Baron, Jean-Marc A. Lobaccaro, Teresa Esposito, Jean-Louis Kemeny, Aurélien J. C. Pommier, Stéphane Fabre, Laurent Morel, Julie Dufour
Publikováno v:
Endocrinology
Endocrinology, Endocrine Society, 2012, 153 (7), pp.3211-3223. ⟨10.1210/en.2011-1996⟩
Endocrinology, 2012, 153 (7), pp.3211-3223. ⟨10.1210/en.2011-1996⟩
Endocrinology 7 (153), 3211-3223. (2012)
Endocrinology, Endocrine Society, 2012, 153 (7), pp.3211-3223. ⟨10.1210/en.2011-1996⟩
Endocrinology, 2012, 153 (7), pp.3211-3223. ⟨10.1210/en.2011-1996⟩
Endocrinology 7 (153), 3211-3223. (2012)
"L'article original est publié par The Endocrine Society"; Benign prostatic hyperplasia is a nonmalignant enlargement of the prostate that commonly occurs in older men. We show that liver X receptor (Lxr)-α knockout mice (lxrα(-/-)) develop ventra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efc8d151698a5294fc01d9231a347d6
https://doi.org/10.1210/en.2011-1996
https://doi.org/10.1210/en.2011-1996
Autor:
Kristina Schoonjans, Aurélie Vega, Jean-Marc A. Lobaccaro, Angélique de Haze, Emmanuelle Martinot, Sander M. Houten, David H. Volle, Geoffroy Marceau, Marine Baptissart, Silvère Baron, Aurélien J. C. Pommier
Publikováno v:
Hepatology (Baltimore, Md.), 60(3), 1054-1065. John Wiley and Sons Ltd
Hepatology
Hepatology, Wiley-Blackwell, 2014, 60 (3), pp.1054--1065. ⟨10.1002/hep.27204⟩
Hepatology (Baltimore Md.)
Hepatology, 2014, 60 (3), pp.1054--1065. ⟨10.1002/hep.27204⟩
Hepatology
Hepatology, Wiley-Blackwell, 2014, 60 (3), pp.1054--1065. ⟨10.1002/hep.27204⟩
Hepatology (Baltimore Md.)
Hepatology, 2014, 60 (3), pp.1054--1065. ⟨10.1002/hep.27204⟩
International audience; Bile acids (BAs) are signaling molecules that are involved in many physiological functions, such as glucose and energy metabolism. These effects are mediated through activation of the nuclear and membrane receptors, farnesoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946351a449c23cbe58abf3b74af4ab37
https://pure.amc.nl/en/publications/bile-acids-alter-male-fertility-through-gproteincoupled-bile-acid-receptor-1-signaling-pathways-in-mice(aad6f931-ded9-4d0f-bb4c-d99271dabdd4).html
https://pure.amc.nl/en/publications/bile-acids-alter-male-fertility-through-gproteincoupled-bile-acid-receptor-1-signaling-pathways-in-mice(aad6f931-ded9-4d0f-bb4c-d99271dabdd4).html
Autor:
Abdelkader Oumeddour, Aurélien J. C. Pommier, Françoise Caira, Jean-Marc A. Lobaccaro, Fatim-Zohra El Hajjaji, David H. Volle, Kevin Mouzat, Emilie Viennois, Julie Dufour, Silvère Baron
Publikováno v:
Expert opinion on therapeutic targets. 15(2)
Liver X receptors (LXR) are transcription factors that belong to the nuclear receptor superfamily. Natural derivatives of cholesterol, known as oxysterols, have been identified as agonistic ligands of LXR. They are thus mainly considered to be intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecabd3169db8c9bc4de303e20d9b54b
https://pubmed.ncbi.nlm.nih.gov/21204733
https://pubmed.ncbi.nlm.nih.gov/21204733
Autor:
Françoise Caira, Y Communal, G. Marceau, Benoit Sion, Jean-Marc A. Lobaccaro, Silvère Baron, C Damon, Sophie Bernard, Aurélien J. C. Pommier, Kevin Mouzat, G Alves, Emilie Viennois
Publikováno v:
Oncogene. 29(18)
Cholesterol is a structural component of lipid rafts within the plasma membrane. These domains, used as platforms for various signaling molecules, regulate cellular processes including cell survival. Cholesterol contents are tightly correlated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8781ffdaa4330456c00c68b24fdd6b
https://pubmed.ncbi.nlm.nih.gov/20190811
https://pubmed.ncbi.nlm.nih.gov/20190811
Autor:
Jean-Marc A. Lobaccaro, Silvère Baron, Georges Alves, Hugues De Boussac, Corinne Lours-Calet, David H. Volle, Aurélien J. C. Pommier, Julie Dufour
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58876 (2013)
PLoS ONE, Vol 8, Iss 3, p e58876 (2013)
Recent studies underline the implication of Liver X Receptors (LXRs) in several prostate diseases such as benign prostatic hyperplasia (BPH) and prostate cancer. In order to understand the molecular mechanisms involved, we derived epithelial cells fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7600d4df8ad61a614044bb82c0b042
https://doi.org/10.1371/journal.pone.0058876
https://doi.org/10.1371/journal.pone.0058876
Autor:
Jean-Marc A. Lobaccaro, Rémi Cadet, Aurélia Ouvrier, Christelle Damon-Soubeyrand, Geoffroy Marceau, Aurélien J. C. Pommier, Fabrice Saez, Joël R. Drevet, Georges Alves, Laurent Janny, Ayhan Kocer, Florence Brugnon
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (11), pp.e26966. ⟨10.1371/journal.pone.0026966⟩
PLoS ONE, 2011, 6 (11), pp.e26966. ⟨10.1371/journal.pone.0026966⟩
PLoS ONE, Vol 6, Iss 11, p e26966 (2011)
PLoS ONE, Public Library of Science, 2011, 6 (11), pp.e26966. ⟨10.1371/journal.pone.0026966⟩
PLoS ONE, 2011, 6 (11), pp.e26966. ⟨10.1371/journal.pone.0026966⟩
PLoS ONE, Vol 6, Iss 11, p e26966 (2011)
This work shows that an overload of dietary cholesterol causes complete infertility in dyslipidemic male mice (the Liver X Receptor-deficient mouse model). Infertility resulted from post-testicular defects affecting the fertilizing potential of sperm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b2027ec84c3c56e9bf75d5f7332903
https://doi.org/10.1371/journal.pone.0026966
https://doi.org/10.1371/journal.pone.0026966
Autor:
Fatim-Zorah El-Hajjaji, Silvère Baron, Aurélia Ouvrier, Jean-Marc A. Lobaccaro, Françoise Caira, Emilie Viennois, Joël R. Drevet, David H. Volle, Abdelkader Oumeddour, Fabrice Saez, Julie Dufour, Aurélien J. C. Pommier
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2011, 1812 (8), pp.974. ⟨10.1016/j.bbadis.2011.02.004⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, 2011, 1812 (8), pp.974. ⟨10.1016/j.bbadis.2011.02.004⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2011, 1812 (8), pp.974. ⟨10.1016/j.bbadis.2011.02.004⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, 2011, 1812 (8), pp.974. ⟨10.1016/j.bbadis.2011.02.004⟩
Liver X receptor (LXR) α and LXRβ belong to the nuclear receptor superfamily. For many years, they have been called orphan receptors, as no natural ligand was identified. In the last decade, the LXR natural ligands have been shown to be oxysterols,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f567936781c76d59baa6a42a8380a333