Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Aurélie de Thonel"'
Autor:
Aurélie de Thonel, Johanna K. Ahlskog, Kevin Daupin, Véronique Dubreuil, Jérémy Berthelet, Carole Chaput, Geoffrey Pires, Camille Leonetti, Ryma Abane, Lluís Cordón Barris, Isabelle Leray, Anna L. Aalto, Sarah Naceri, Marine Cordonnier, Carène Benasolo, Matthieu Sanial, Agathe Duchateau, Anniina Vihervaara, Mikael C. Puustinen, Federico Miozzo, Patricia Fergelot, Élise Lebigot, Alain Verloes, Pierre Gressens, Didier Lacombe, Jessica Gobbo, Carmen Garrido, Sandy D. Westerheide, Laurent David, Michel Petitjean, Olivier Taboureau, Fernando Rodrigues-Lima, Sandrine Passemard, Délara Sabéran-Djoneidi, Laurent Nguyen, Madeline Lancaster, Lea Sistonen, Valérie Mezger
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Abstract Patients carrying autosomal dominant mutations in the histone/lysine acetyl transferases CBP or EP300 develop a neurodevelopmental disorder: Rubinstein-Taybi syndrome (RSTS). The biological pathways underlying these neurodevelopmental defect
Externí odkaz:
https://doaj.org/article/9f7e7aecc3a8463b9a5732585bfbb110
Autor:
Aurélie de Thonel, Johanna K. Ahlskog, Kevin Daupin, Véronique Dubreuil, Jérémy Berthelet, Carole Chaput, Geoffrey Pires, Camille Leonetti, Ryma Abane, Lluís Cordón Barris, Isabelle Leray, Anna L. Aalto, Sarah Naceri, Marine Cordonnier, Carène Benasolo, Matthieu Sanial, Agathe Duchateau, Anniina Vihervaara, Mikael C. Puustinen, Federico Miozzo, Patricia Fergelot, Élise Lebigot, Alain Verloes, Pierre Gressens, Didier Lacombe, Jessica Gobbo, Carmen Garrido, Sandy D. Westerheide, Laurent David, Michel Petitjean, Olivier Taboureau, Fernando Rodrigues-Lima, Sandrine Passemard, Délara Sabéran-Djoneidi, Laurent Nguyen, Madeline Lancaster, Lea Sistonen, Valérie Mezger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4589c26879ce46d1a03bf9df8d0e1d72
Autor:
Margaux Sevin, Lucia Kubovcakova, Nicolas Pernet, Sébastien Causse, Franck Vitte, Jean Luc Villeval, Catherine Lacout, Marine Cordonnier, Fernando Rodrigues-Lima, Gaétan Chanteloup, Matthieu Mosca, Marie-Lorraine Chrétien, Jean Noël Bastie, Sylvain Audia, Paul Sagot, Selim Ramla, Laurent Martin, Martin Gleave, Valérie Mezger, Radek Skoda, Isabelle Plo, Carmen Garrido, François Girodon, Aurélie de Thonel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Myelofibrosis is a chronic degenerative disorder characterized by progressive bone marrow fibrosis. Here, the authors show that the chaperone HSP27 contributes to myelofibrosis via regulation of the JAK2/STAT5 pathway, and that antisense oligonucleot
Externí odkaz:
https://doaj.org/article/7cd28d8985ce47f7a61f528b7a0f931b
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Myeloproliferative neoplasms (MPN) are clonal stem cell disorders that lead to the excessive production of one or more blood cell lineages. It has been reported that, in most MPN, inflammatory cytokines are frequently increased, indicating that infla
Externí odkaz:
https://doaj.org/article/778f37b8460b4c44beba44b04675a6d1
Publikováno v:
Tumor Suppressor Par-4 ISBN: 9783030735715
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be9621a42e478237b3c6ca5c00525cb5
https://doi.org/10.1007/978-3-030-73572-2_6
https://doi.org/10.1007/978-3-030-73572-2_6
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2020, 725, pp.134895. ⟨10.1016/j.neulet.2020.134895⟩
Neuroscience Letters, Elsevier, 2020, 725, pp.134895. ⟨10.1016/j.neulet.2020.134895⟩
International audience; The Heat Shock Factors (HSFs) have been historically identified as a family of transcription factors that are activated and work in a stress-responsive manner, after exposure to a large variety of stimuli. However, they are al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd141eaf917ba859a560022ddd14db07
https://hal-cnrs.archives-ouvertes.fr/hal-03030352
https://hal-cnrs.archives-ouvertes.fr/hal-03030352
Autor:
Jérôme Paggetti, Burhan Uyanik, Oleg N. Demidov, Alexandre M.M. Dias, Laurence Dubrez, Carmen Garrido, Gaëtan Chanteloup, Sebastien Causse, Baptiste Dumetier, Etienne Moussay, Guillaume Marcion, Christophe Boudesco, Jessica Gobbo, Lucile Dondaine, Aurélie de Thonel, Bogdan B. Grigorash, Gustavo J. Gozzi, Céline Mirjolet, Romain Douhard
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2019, 38 (15), pp.2767-2777. ⟨10.1038/s41388-018-0616-2⟩
Oncogene, Nature Publishing Group, In press, ⟨10.1038/s41388-018-0616-2⟩
Oncogene, Nature Publishing Group, 2019, 38 (15), pp.2767-2777. ⟨10.1038/s41388-018-0616-2⟩
Oncogene, Nature Publishing Group, In press, ⟨10.1038/s41388-018-0616-2⟩
International audience; A multicenter clinical study demonstrated the presence of a loss-of-function HSP110 mutation in about 15% of colorectal cancers, which resulted from an alternative splicing and was produced at the detriment of wild-type HSP110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64f37b8f843f1a3bbd8b6d3b64bf440
https://hal-cnrs.archives-ouvertes.fr/hal-03030351
https://hal-cnrs.archives-ouvertes.fr/hal-03030351
Autor:
Jenny Joutsen, Eva Henriksson, Délara Sabéran-Djoneidi, Lea Sistonen, Marek A. Budzynski, Jean-Paul Concordet, Alejandro J. Da Silva, Aurélie de Thonel, Jens C. Luoto, Valérie Mezger
Cellular ability to maintain proper protein homeostasis (proteostasis) is essential for survival upon protein-damaging conditions. Heat shock transcription factor 2 (HSF2) is one of the human HSFs activated in response to proteotoxic stress. HSF2 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00a103f2ce8f453ef1e067525addba4
Autor:
Carène Benasolo, Élise Lebigot, Jérémy Berthelet, Madeline A. Lancaster, Federico Miozzo, Didier Lacombe, Sarah Naceri, Déborah Bouvier, Olivier Taboureau, Aurélie de Thonel, Johanna K. Ahlskog, Véronique Dubreuil, Mathilde Henry, Pierre Gressens, Sandrine Passemart, Matthieu Sanial, Jean-Paul Concordet, Délara Sabéran-Djoneidi, Patricia Fergelot, Marion Cordonnier, Jessica Gobbo, Mikael C. Puustinen, Anna L. Aalto, Agathe Duchateau, Michel Petitjean, Ryma Abane, Alain Verloes, Lea Sistonen, Carmen Garrido, Valérie Mezger, Sandy D. Westerheide, Anniina Vihervaara, Fernando Rodrigues-Uma, Geoffrey Pires
SUMMARYCells respond to protein-damaging insults by activating heat shock factors (HSFs), key transcription factors of proteostasis. Abnormal HSF protein levels occur in cancer and neurodegenerative disorders, highlighting the importance of the tight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7632caa55526350c6374166293dbf678
Autor:
Isabelle Plo, Marine Cordonnier, Martin E. Gleave, Lucia Kubovcakova, Aurélie de Thonel, Selim Ramla, Jean Noel Bastie, Paul Sagot, François Girodon, Valérie Mezger, Jean-Luc Villeval, Marie-Lorraine Chretien, Franck Vitte, Laurent Martin, Matthieu Mosca, Fernando Rodrigues-Lima, Margaux Sevin, Sylvain Audia, Gaëtan Chanteloup, Nicolas Pernet, Carmen Garrido, Radek C. Skoda, Catherine Lacout, Sebastien Causse
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1431. ⟨10.1038/s41467-018-03627-9⟩
Nature Communications, 2018, 9 (1), pp.1431. ⟨10.1038/s41467-018-03627-9⟩
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-03627-9⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1431. ⟨10.1038/s41467-018-03627-9⟩
Nature Communications, 2018, 9 (1), pp.1431. ⟨10.1038/s41467-018-03627-9⟩
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-03627-9⟩
Heat shock protein 27 (HSP27/HSPB1) is a stress-inducible chaperone that facilitates cancer development by its proliferative and anti-apoptotic functions. The OGX-427 antisense oligonucleotide against HSP27 has been reported to be beneficial against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b995f8e0680aca1f2604f10d8e27a48
https://hal.archives-ouvertes.fr/hal-02929931
https://hal.archives-ouvertes.fr/hal-02929931