Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Aurélie Kamoun"'
Autor:
Charlie Saillard, Rémy Dubois, Oussama Tchita, Nicolas Loiseau, Thierry Garcia, Aurélie Adriansen, Séverine Carpentier, Joelle Reyre, Diana Enea, Katharina von Loga, Aurélie Kamoun, Stéphane Rossat, Corentin Wiscart, Meriem Sefta, Michaël Auffret, Lionel Guillou, Arnaud Fouillet, Jakob Nikolas Kather, Magali Svrcek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Mismatch Repair Deficiency (dMMR)/Microsatellite Instability (MSI) is a key biomarker in colorectal cancer (CRC). Universal screening of CRC patients for MSI status is now recommended, but contributes to increased workload for pathologists a
Externí odkaz:
https://doaj.org/article/3bd083f2ea1441ccadbadb50db32184d
Autor:
Hervé Lang, Claire Béraud, Luc Cabel, Jacqueline Fontugne, Myriam Lassalle, Clémentine Krucker, Florent Dufour, Clarice S. Groeneveld, Victoria Dixon, Xiangyu Meng, Aurélie Kamoun, Elodie Chapeaublanc, Aurélien De Reynies, Xavier Gamé, Pascal Rischmann, Ivan Bieche, Julien Masliah-Planchon, Romane Beaurepere, Yves Allory, Véronique Lindner, Yolande Misseri, François Radvanyi, Philippe Lluel, Isabelle Bernard-Pierrot, Thierry Massfelder
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMuscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are
Externí odkaz:
https://doaj.org/article/530d7616638a4e26a742ecd5e89e062d
Autor:
Benoît Schmauch, Alberto Romagnoni, Elodie Pronier, Charlie Saillard, Pascale Maillé, Julien Calderaro, Aurélie Kamoun, Meriem Sefta, Sylvain Toldo, Mikhail Zaslavskiy, Thomas Clozel, Matahi Moarii, Pierre Courtiol, Gilles Wainrib
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
RNA-sequencing of tumour tissue can provide important diagnostic and prognostic information but this is costly and not routinely performed in all clinical settings. Here, the authors show that whole slide histology slides—part of routine care—can
Externí odkaz:
https://doaj.org/article/d4db17b3e50d44079b75aaf30a53561e
Autor:
Natacha Rochel, Clémentine Krucker, Laure Coutos-Thévenot, Judit Osz, Ruiyun Zhang, Elodie Guyon, Wayne Zita, Séverin Vanthong, Oscar Alba Hernandez, Maxime Bourguet, Kays Al Badawy, Florent Dufour, Carole Peluso-Iltis, Syrine Heckler-Beji, Annick Dejaegere, Aurélie Kamoun, Aurélien de Reyniès, Yann Neuzillet, Sandra Rebouissou, Claire Béraud, Hervé Lang, Thierry Massfelder, Yves Allory, Sarah Cianférani, Roland H. Stote, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Activation of the PPARγ/RXRα pathway in luminal bladder cancers has mainly been linked to PPARG gene amplifications and activating point mutations in RXRα. Here, the authors identify recurrent PPARγ mutations with similar effects and elucidate th
Externí odkaz:
https://doaj.org/article/5e44a383003c4ce0b87b4a701664d7c3
Autor:
Aurélie Kamoun, Ahmed Idbaih, Caroline Dehais, Nabila Elarouci, Catherine Carpentier, Eric Letouzé, Carole Colin, Karima Mokhtari, Anne Jouvet, Emmanuelle Uro-Coste, Nadine Martin-Duverneuil, Marc Sanson, Jean-Yves Delattre, Dominique Figarella-Branger, Aurélien de Reyniès, François Ducray, POLA network
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Oligodendroglial tumours are characterized into three different molecular subtypes. Here, the authors use genomic data to identify a further three subgroups of 1p/19q co-deleted tumours and demonstrate an association with an aggressive phenotype.
Externí odkaz:
https://doaj.org/article/12858698deb1459690d2e7186bf25ef2
Autor:
Anne Biton, Isabelle Bernard-Pierrot, Yinjun Lou, Clémentine Krucker, Elodie Chapeaublanc, Carlota Rubio-Pérez, Nuria López-Bigas, Aurélie Kamoun, Yann Neuzillet, Pierre Gestraud, Luca Grieco, Sandra Rebouissou, Aurélien de Reyniès, Simone Benhamou, Thierry Lebret, Jennifer Southgate, Emmanuel Barillot, Yves Allory, Andrei Zinovyev, François Radvanyi
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1235-1245 (2014)
Extracting relevant information from large-scale data offers unprecedented opportunities in cancerology. We applied independent component analysis (ICA) to bladder cancer transcriptome data sets and interpreted the components using gene enrichment an
Externí odkaz:
https://doaj.org/article/fc9494082fea48fdaec4ebd243c8bd7f
Autor:
Ming-Jun Shi, Jacqueline Fontugne, Aura Moreno-Vega, Xiang-Yu Meng, Clarice Groeneveld, Florent Dufour, Aurélie Kamoun, Sia Viborg Lindskrog, Luc Cabel, Clémentine Krucker, Audrey Rapinat, Claire Dunois-Larde, May-Linda Lepage, Elodie Chapeaublanc, Olivier Levrel, Victoria Dixon, Thierry Lebret, Anna Almeida, Aurélien De Reynies, Natacha Rochel, Lars Dyrskjøt, Yves Allory, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
European Urology
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
Background: Bladder cancer (BCa) is more common in men and presents differences in molecular subtypes based on sex. Fibroblast growth factor receptor 3 (FGFR3) mutations are enriched in the luminal papillary muscle-invasive BCa (MIBC) and non-MIBC su
Autor:
Charlie Saillard, Rémy Dubois, Oussama Tchita, Nicolas Loiseau, Thierry Garcia, Aurélie Adriansen, Séverine Carpentier, Joelle Reyre, Diana Enea, Aurélie Kamoun, Stéphane Rossat, Meriem Sefta, Michael Auffret, Lionel Guillou, Arnaud Fouillet, Jakob Nikolas Kather, Magali Svrcek
ObjectiveMismatch Repair Deficiency (dMMR) / Microsatellite Instability (MSI) is a key biomarker in colorectal cancer (CRC). Universal screening of CRC patients for dMMR/MSI status is now recommended, but contributes to increased workload for patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf2ec268191a2addb6aa0e4251741f6
https://doi.org/10.1101/2022.11.17.22282460
https://doi.org/10.1101/2022.11.17.22282460
Autor:
Elodie Chapeaublanc, A. De Reynies, O. Levrel, Isabelle Bernard-Pierrot, Florent Dufour, Aurélie Kamoun, Yves Allory, M. Shi, Sia Viborg Lindskrog, Lars Dyrskjøt, T. Lebret, J. Fontugne, F. Radvanyi, C. Dunois-Larde, M.-L. Lapage, Aura Moreno-Vega, X.-Y. Meng, Audrey Rapinat, A. Almeida
BackgroundFGFR3 mutations are among the most frequent genetic alterations in bladder cancer and are enriched in the luminal papillary subtype of muscle-invasive tumors (MIBC) and luminal-like classes 1 and 3 of non-MIBC. To study their oncogenic prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e793114ebb674ca8932198be6a1cfe99
https://doi.org/10.1101/2021.09.02.458778
https://doi.org/10.1101/2021.09.02.458778
Autor:
Hikmat Al-Ahmadie, Ewan A. Gibb, Qianxing Mo, Colin P.N. Dinney, A Arlene Siefker-Radtke, Jordan Kardos, Thomas Powles, Yves Allory, William Y. Kim, Joaquim Bellmunt, Katherine A. Hoadley, Arndt Hartmann, Roland Seiler, Seth P. Lerner, Isabelle Bernard-Pierrot, Núria Malats, Jacqueline Fontugne, Francisco X. Real, Ann Taber, John N. Weinstein, Mattias Aine, Gottfrid Sjödahl, Nanor Sirab, Aurélie Kamoun, Peter C. Black, Lars Dyrskjøt, Bogdan Czerniak, Keith S. Chan, Thierry Lebret, A. Gordon Robertson, Fredrik Liedberg, David J. Kwiatkowski, Mattias Höglund, Mauro A. A. Castro, Clarice S. Groeneveld, Pontus Eriksson, Jaegil Kim, François Radvanyi, Alexandre R. Zlotta, Aurélien de Reyniès, Woonyoung Choi, David J. McConkey
Publikováno v:
Kamoun, A, de Reyniès, A, Allory, Y, Sjödahl, G, Robertson, A G, Seiler, R, Hoadley, K A, Groeneveld, C S, Al-Ahmadie, H, Choi, W, Castro, M A A, Fontugne, J, Eriksson, P, Mo, Q, Kardos, J, Zlotta, A, Hartmann, A, Dinney, C P, Bellmunt, J, Powles, T, Malats, N, Chan, K S, Kim, W Y, McConkey, D J, Black, P C, Dyrskjøt, L, Höglund, M, Lerner, S P, Real, F X, Radvanyi, F, Aine, M, Bernard-Pierrot, I, Czerniak, B, Gibb, E A, Kim, J, Kwiatkowski, D J, Lebret, T, Liedberg, F, Siefker-Radtke, A A, Sirab, N, Taber, A & Weinstein, J N 2020, ' Reply To Kenneth B. Yatai, Mark J. Dunning, Dennis Wang. Consensus Genomic Subtypes of Muscle-invasive Bladder Cancer : A Step in the Right Direction but Still a Long Way To Go. Eur Urol 2020;77:434–5 ', European Urology, vol. 77, no. 4, pp. 436-438 . https://doi.org/10.1016/j.eururo.2019.12.014
In our study the Bladder Cancer Molecular Taxonomy Group collaborated to extend a first consensus report, addressing the need for a consensus molecular classification for muscle-invasive bladder cancer (MIBC) that would support basic research and cli