Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aurélie Darbois"'
Autor:
Anastasia du Halgouet, Aurélie Darbois, Aurélia Alphonse, Thomas Yvorra, Ludovic Colombeau, Raphaël Rodriguez, Olivier Lantz, Marion Salou
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102419- (2023)
Summary: Generating knockout mice for target molecules in specific T cell populations, without subset-specific promoters, is time-consuming and costly. Here, we describe steps for enriching mucosal-associated invariant T cells from the thymus, expand
Externí odkaz:
https://doaj.org/article/62d48bb00cef4386ac2793eaa83838bc
Autor:
Ruby Alonso, Héloïse Flament, Sébastien Lemoine, Christine Sedlik, Emanuel Bottasso, Isabel Péguillet, Virginie Prémel, Jordan Denizeau, Marion Salou, Aurélie Darbois, Nicolás Gonzalo Núñez, Benoit Salomon, David Gross, Eliane Piaggio, Olivier Lantz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Tumor neoantigens can be drained to the lymph nodes, but the nature and the significance of the induced immune responses are still unclear. Here the authors use a mouse genetic tumor model to show that tumor-specific CD4 T cells can become anergic or
Externí odkaz:
https://doaj.org/article/74b8aa3d1148474e8cae7856e61a4c79
Autor:
Anastasia Du Halgouet, Aurélie Darbois, Mansour Alkobtawi, Martin Mestdagh, Aurélia Alphonse, Virginie Premel, Dietmar Zeiss, Yara El Morr, Hélène Bugaut, François Legoux, Laetitia Perrin, Selim Aractingi, Rachel Golub, Olivier Lantz, Marion Salou
Publikováno v:
SSRN Electronic Journal.
Autor:
Aurélien, Sutra Del Galy, Silvia, Menegatti, Jaime, Fuentealba, Francesca, Lucibello, Laetitia, Perrin, Julie, Helft, Aurélie, Darbois, Michael, Saitakis, Jimena, Tosello, Derek, Rookhuizen, Marc, Deloger, Pierre, Gestraud, Gérard, Socié, Sebastian, Amigorena, Olivier, Lantz, Laurie, Menger
Publikováno v:
Science immunology. 6(66)
Although CD8
Autor:
Manal Sarkis, Jules Gilet, Kristina Niort, François Legoux, Yara El Morr, Olivier Lantz, Emanuele Procopio, Aurélie Balvay, Ahmed El Marjou, Aurélie Darbois, Frédéric Schmidt, Anne Foussier, Déborah Bellet, Celine Daviaud, Marion Salou, Sylvie Rabot, Bernhard Ryffel
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2019, 366 (6464), pp.494-499. ⟨10.1126/science.aaw2719⟩
Science, American Association for the Advancement of Science, 2019, 366 (6464), pp.494-499. ⟨10.1126/science.aaw2719⟩
Commensals rule the MAITrix Mucosal-associated invariant T (MAIT) cells play an important role in mucosal homeostasis. MAIT cells recognize microbial small molecules presented by the major histocompatibility complex class Ib molecule MR1. MAIT cells
Autor:
Anne-Gaëlle Goubet, Jules Gilet, Emanuele Procopio, Aurélie Darbois, Wilfrid Richer, Celine Daviaud, Virginie Premel, Anastasia du Halgouet, Marion Salou, François Legoux, Ruby Alonso, Olivier Lantz, Laurie Menger
Publikováno v:
The Journal of Experimental Medicine
Salou et al. wondered what could differentiate MAIT and NKT cells, if not for TCR specificity. Once split according to RORγt and T-bet–expressing subsets, MAIT and NKT share almost identical transcriptional programs acquired in the thymus, which r
Autor:
Jaime Fuentealba, Gérard Socié, Laurie Menger, Jimena Tosello, Marc Deloger, Silvia Menegatti, Olivier Lantz, Francesca Lucibello, Michael Saitakis, Aurélie Darbois, Pierre Gestraud, Sebastian Amigorena, Laetitia Perrin, Julie Helft, Aurélien Sutra Del Galy, Derek Rookhuizen
SummaryThe expansion of antigen experienced CD4+ T cells is limited by intrinsic factors. Using in vivo genome-wide CRISPR-Cas9 screens, we identified SOCS1 as a non-redundant checkpoint imposing a brake on CD4+ T-cell proliferation upon rechallenge.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c044a4db82af85a71f636d6b57711dd
https://doi.org/10.1101/2021.04.12.439455
https://doi.org/10.1101/2021.04.12.439455
Autor:
Isabel Péguillet, Eliane Piaggio, David Alexandre Gross, Virginie Premel, Ruby Alonso, Héloïse Flament, Olivier Lantz, Emanuel Bottasso, Nicolás Gonzalo Núñez, Aurélie Darbois, Jordan Denizeau, Marion Salou, Christine Sedlik, Benoît L. Salomon, Sébastien Lemoine
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9, pp.2113. ⟨10.1038/s41467-018-04524-x⟩
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications, Nature Publishing Group, 2018, 9, pp.2113. ⟨10.1038/s41467-018-04524-x⟩
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
CD4+ T cell antitumor responses have mostly been studied in transplanted tumors expressing secreted model antigens (Ags), while most mutated proteins in human cancers are not secreted. The fate of Ag-specific CD4+ T cells recognizing a cytoplasmic Ag
Autor:
Anastasia du Halgouet, Aurélie Darbois, Mansour Alkobtawi, Martin Mestdagh, Aurélia Alphonse, Virginie Premel, Thomas Yvorra, Ludovic Colombeau, Raphaël Rodriguez, Dietmar Zaiss, Yara El Morr, Hélène Bugaut, François Legoux, Laetitia Perrin, Selim Aractingi, Rachel Golub, Olivier Lantz, Marion Salou
Publikováno v:
Immunity
Immunity, 2023, 56 (1), pp.78-92.e6. ⟨10.1016/j.immuni.2022.12.004⟩
Immunity, 2023, 56 (1), pp.78-92.e6. ⟨10.1016/j.immuni.2022.12.004⟩
International audience; Tissue repair processes maintain proper organ function following mechanical or infection-related damage. In addition to antibacterial properties, mucosal associated invariant T (MAIT) cells express a tissue repair transcriptom