Výsledky vyhledávání - "Aurélie Borrull"

Beta-arrestins operate an on/off control switch for focal adhesion kinase activity

Autor: Stefano Marullo, Aurélie Borrull, Mireille Lambert, Isaure Lot, Alexandre Beautrait, Michel Bouvier, Revu Ann Alexander, Kusumika Saha, Eleonore Decosta, Mark G.H. Scott, Atef Asnacios, Hervé Enslen, Guillaume Abadie, Hiroyuki Kobayashi

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2020, 77 (24), pp.5259-5279. ⟨10.1007/s00018-020-03471-5⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2020, Epub ahead of print. ⟨10.1007/s00018-020-03471-5⟩
Cellular and Molecular Life Sciences, 2020, Epub ahead of print. ⟨10.1007/s00018-020-03471-5⟩

International audience; Focal adhesion kinase (FAK) regulates key biological processes downstream of G protein-coupled receptors (GPCRs) in normal and cancer cells, but the modes of kinase activation by these receptors remain unclear. We report that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343d1ead466b69d230fa38200280fb6a
https://hal.archives-ouvertes.fr/hal-03031947

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Generation and characterization of rendomab-B1, a monoclonal antibody displaying potent and specific antagonism of the human endothelin B receptor

Autor: Aurélie Borrull, Patricia Lamourette, Jean-Yves Couraud, Frédérique Deshayes, Frédéric Ducancel, Bertrand Allard, Didier Boquet, Fabienne Priam, Anne Wijkhuisen

Publikováno v: mAbs
mAbs, 2013, 5 (1), pp.56-69. ⟨10.4161/mabs.22696⟩
mAbs, Taylor & Francis, 2013, 5 (1), pp.56-69. ⟨10.4161/mabs.22696⟩

International audience; Endothelin B receptor (ETBR) is a G protein-coupled receptor able to bind equally to the three identified human endothelin peptides. It is expressed primarily on vascular endothelial cells and involved in various physiological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7ebffe0d6ef4aa62028ecf8384743f
https://doi.org/10.4161/mabs.22696

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Rendomab B4, a monoclonal antibody that discriminates the human endothelin B receptor of melanoma cells and inhibits their migration

Autor: Zahra Tanfin, Bertrand Allard, Wided Birouk, Aurélie Borrull, Anne Wijkhuisen, Didier Boquet, Denis Leiber, Jean-Yves Couraud, Philippe Robin, Frédéric Ducancel, Amaury Herbet, Patricia Lamourette

Publikováno v: mAbs
mAbs, Taylor & Francis, 2016, 8 (7), pp.1371-1385. ⟨10.1080/19420862.2016.1208865⟩
mAbs, 2016, 8 (7), pp.1371-1385. ⟨10.1080/19420862.2016.1208865⟩

Auteur correspondant (avec Didier Boquet) : Philippe Robin (philippe.robin@cea.fr, philippe.robin@u-psud.fr); International audience; Metastatic melanoma is an aggressive cancer with a poor prognostic, and the design of new targeted drugs to treat me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243b1a6b2d3e61659fff6255a35ff8b8
https://hal.archives-ouvertes.fr/hal-02545400

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Nanog and Oct4 overexpression increases motility and transmigration of melanoma cells

Autor: Catherine Alcaide-Loridan, Jessica Lauriol, Sandrine Middendorp, Stephanie Ghislin, Frédérique Deshayes, Aurélie Borrull

Publikováno v: Journal of Cancer Research and Clinical Oncology
Journal of Cancer Research and Clinical Oncology, Springer Verlag, 2012, 138 (7), pp.1145-54. ⟨10.1007/s00432-012-1186-2⟩
Journal of Cancer Research and Clinical Oncology, 2012, 138 (7), pp.1145-54. ⟨10.1007/s00432-012-1186-2⟩

International audience; PURPOSE: Melanoma tumors are highly heterogeneous and can undergo phenotypic modifications depending on their plasticity and the microenvironment, with shifts between proliferative and invasive states. We have shown that melan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7166e5d098a5abf4ed658de8f4de42
https://pubmed.ncbi.nlm.nih.gov/22406932

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