Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Aurélie Baudet"'
Autor:
Simon Hultmark, Aurélie Baudet, Ludwig Schmiderer, Pavan Prabhala, Sara Palma-Tortosa, Carl Sandén, Thoas Fioretos, Rajkumar Sasidharan, Christer Larsson, Sören Lehmann, Gunnar Juliusson, Fredrik Ek, Mattias Magnusson
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
Combination treatment has proven effective for patients with acute promyelocytic leukemia, exemplifying the importance of therapy targeting multiple components of oncogenic regulation for a successful outcome. However, recent studies have shown that
Externí odkaz:
https://doaj.org/article/eb07afe4d0a343629492a6a4e40ce48b
Autor:
Roman Galeev, Aurélie Baudet, Praveen Kumar, Alexandra Rundberg Nilsson, Björn Nilsson, Shamit Soneji, Therese Törngren, Åke Borg, Anders Kvist, Jonas Larsson
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2988-3000 (2016)
To gain insights into the regulatory mechanisms of hematopoietic stem cells (HSCs), we employed a genome-wide RNAi screen in human cord-blood derived cells and identified candidate genes whose knockdown maintained the HSC phenotype during culture. A
Externí odkaz:
https://doaj.org/article/ba32c2d6ac454633a0b25ed4e8f1173a
Autor:
Mehrnaz Safaee Talkhoncheh, Agatheeswaran Subramaniam, Mattias Magnusson, Praveen Kumar, Jonas Larsson, Aurélie Baudet
Publikováno v:
Haematologica, Vol 103, Iss 9 (2018)
Despite extensive studies, defining culture conditions in which hematopoietic stem cells can be expanded ex vivo has been challenging. Here we show that chemical inhibition of the NF-κB signaling pathway leads to a significant improvement of hematop
Externí odkaz:
https://doaj.org/article/46c1c5c53d1b45b1bc832053e5908e32
Autor:
Katarzyna Radke, Karin Hansson, Jani Saarela, Aleksandr Ianevski, Philipp Ianevski, Aurélie Baudet, Mattias Magnusson, Daniel Bexell
Publikováno v:
Cancer Research. 82:3892-3892
Neuroblastoma is a childhood solid tumor commonly located in the adrenal gland. High-risk neuroblastoma patients undergo multidrug and multi-interventional treatment but despite these efforts many patients develop resistance to chemotherapy and event
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1856270550650fa441c466e123744a69
https://doi.org/10.1158/1538-7445.am2022-3892
https://doi.org/10.1158/1538-7445.am2022-3892
Autor:
David Bryder, Magnusson M, Komorowska K, Aurélie Baudet, Järås M, Gunnar Juliusson, Hultmark S, Chapellier M, Miharada K, Jonas Larsson
The processes regulating hematopoietic stem cells (HSC) during aging are not fully understood1, but it is clear that the incidence of hematological malignancies increases with age, highlighting the importance of unravelling the cellular and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0517aa94f29bd296d94d30afe0dbd7e5
https://doi.org/10.1101/2021.03.05.434034
https://doi.org/10.1101/2021.03.05.434034
Autor:
Shamit Soneji, Mattias Magnusson, Aurélie Baudet, Josef Davidsson, Jörg Cammenga, Gunnar Juliusson, Roger Olsson, Fredrik Ek
Publikováno v:
British Journal of Haematology. 175:342-346
Small molecule screen identifies differentiation-promoting compounds targeting genetically diverse acute myeloid leukaemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d87239aaa5c9ed5649526f9a78e9ff
https://doi.org/10.1111/bjh.13851
https://doi.org/10.1111/bjh.13851
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1622
Identifying the genes and pathways that regulate self-renewal and differentiation in somatic stem cells is a central goal in stem cell and cancer biology. Here, we describe a method for RNA interference (RNAi)-based screens combined with next-generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cb8275df8e6f1bc72500a33128cbd8e
https://pubmed.ncbi.nlm.nih.gov/28674799
https://pubmed.ncbi.nlm.nih.gov/28674799
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971060
Identifying the genes and pathways that regulate self-renewal and differentiation in somatic stem cells is a central goal in stem cell and cancer biology. Here, we describe a method for RNA interference (RNAi)-based screens combined with next-generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3bd8e4f13b55baee19ed5174f4369c0
https://doi.org/10.1007/978-1-4939-7108-4_3
https://doi.org/10.1007/978-1-4939-7108-4_3
Autor:
Aurélie Baudet, Mattias Magnusson, Gunnar Juliusson, Hultmark Simon, Marcus Järås, Karolina Komorowska, Marion Chapellier
Publikováno v:
Blood. 134:2466-2466
The transcription factor Hepatic leukemia factor (HLF), initially identified as part of a leukemic fusion protein (E2A-HLF) causing B-lymphoid leukemia in children, is expressed in a wide range of tissues. In the mouse hematopoietic system, HLF is hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578b980788f24938927a18b1d34e594c
https://doi.org/10.1182/blood-2019-122661
https://doi.org/10.1182/blood-2019-122661
Publikováno v:
Journal of Neuroscience Methods. 218:25-28
Glial cell-line derived neurotrophic factor (GDNF) is a secreted protein with great therapeutic potential. However, in order to analyse the interactions between GDNF and its receptors, researchers have been mostly dependent of radioactive binding ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b37fa8ab2f16c3190e46d461cc097e
https://doi.org/10.1016/j.jneumeth.2013.04.006
https://doi.org/10.1016/j.jneumeth.2013.04.006