Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Aurélie Barrail"'
Autor:
Caroline Passaes, Delphine Desjardins, Anaïs Chapel, Valérie Monceaux, Julien Lemaitre, Adeline Mélard, Federico Perdomo-Celis, Cyril Planchais, Maël Gourvès, Nastasia Dimant, Annie David, Nathalie Dereuddre-Bosquet, Aurélie Barrail-Tran, Hélène Gouget, Céline Guillaume, Francis Relouzat, Olivier Lambotte, Jérémie Guedj, Michaela Müller-Trutwin, Hugo Mouquet, Christine Rouzioux, Véronique Avettand-Fenoël, Roger Le Grand, Asier Sáez-Cirión
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract HIV remission can be achieved in some people, called post-treatment HIV controllers, after antiretroviral treatment discontinuation. Treatment initiation close to the time of infection was suggested to favor post-treatment control, but the c
Externí odkaz:
https://doaj.org/article/661b86229b42429d8450453e606a9ab0
Autor:
François Riglet, Julie Bertrand, Aurélie Barrail-Tran, Céline Verstuyft, Hugues Michelon, Henri Benech, Antoine Durrbach, Valérie Furlan, Caroline Barau
Publikováno v:
Drugs in R&D, Vol 20, Iss 4, Pp 331-342 (2020)
Abstract Background and Objective Mycophenolate mofetil is widely used in kidney transplant recipients. Mycophenolate mofetil is hydrolysed by blood esterases to mycophenolic acid (MPA), the active drug. Although MPA therapeutic drug monitoring has b
Externí odkaz:
https://doaj.org/article/aebc7369cc8943ce95212329c4a83a17
Autor:
Thibaut Gelé, Hélène Gouget, Nathalie Dereuddre-Bosquet, Valérie Furlan, Roger Le Grand, Olivier Lambotte, Delphine Desjardins, Aurélie Barrail-Tran
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2282 (2022)
The development of animal models undergoing long-term antiretroviral treatment (ART) makes it possible to understand a number of immunological, virological, and pharmacological issues, key factors in the management of HIV infection. We aimed to pharm
Externí odkaz:
https://doaj.org/article/c22b7677f8bc4894bae9d1f72940c31a
Autor:
Aude Mausoléo, Anaelle Olivo, Delphine Desjardins, Asier Sáez-Cirión, Aurélie Barrail-Tran, Véronique Avettand-Fenoel, Nicolas Noël, Claire Lagathu, Véronique Béréziat, Roger Le Grand, Olivier Lambotte, Christine Bourgeois
Publikováno v:
Cells, Vol 11, Iss 19, p 3104 (2022)
During chronic SIV/HIV infection, adipose tissue (AT) is the target of both antiretroviral treatment (ART) and the virus. AT might subsequently contribute to the low-grade systemic inflammation observed in patients on ART. To evaluate the inflammator
Externí odkaz:
https://doaj.org/article/e0ee238012fe4f6db37af0be3b9f8ffc
Autor:
Kenza Ngono Ayissi, Jennifer Gorwood, Laura Le Pelletier, Christine Bourgeois, Carine Beaupère, Martine Auclair, Roberta Foresti, Roberto Motterlini, Michael Atlan, Aurélie Barrail-Tran, Roger Le Grand, Delphine Desjardins, Bruno Fève, Olivier Lambotte, Jacqueline Capeau, Véronique Béréziat, Claire Lagathu
Publikováno v:
Cells, Vol 11, Iss 11, p 1841 (2022)
For people living with HIV, treatment with integrase-strand-transfer-inhibitors (INSTIs) can promote adipose tissue (AT) gain. We previously demonstrated that INSTIs can induce hypertrophy and fibrosis in AT of macaques and humans. By promoting energ
Externí odkaz:
https://doaj.org/article/55ba594c6daf431e8bcdf4805ef78500
Autor:
Christine Bourgeois, Jennifer Gorwood, Aurélie Barrail-Tran, Claire Lagathu, Jacqueline Capeau, Delphine Desjardins, Roger Le Grand, Abderaouf Damouche, Véronique Béréziat, Olivier Lambotte
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Although white AT can contribute to anti-infectious immune responses, it can also be targeted and perturbed by pathogens. The AT’s immune involvement is primarily due to strong pro-inflammatory responses (with both local and paracrine effects), and
Externí odkaz:
https://doaj.org/article/92cc082d2bba4a499bc583d3eb0bf28a
Autor:
Nguyen Thi Ngoc Lan, Nguyen Thi Nguyet Thu, Aurélie Barrail-Tran, Nguyen Hong Duc, Nguyen Ngoc Lan, Didier Laureillard, Truong Thi Xuan Lien, Laurence Borand, Catherine Quillet, Catherine Connolly, Dominique Lagarde, Alexander Pym, Christian Lienhardt, Nguyen Huy Dung, Anne-Marie Taburet, Anthony D Harries
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84866 (2014)
Rifampicin and protease inhibitors are difficult to use concomitantly in patients with HIV-associated tuberculosis because of drug-drug interactions. Rifabutin has been proposed as an alternative rifamycin, but there is concern that the current recom
Externí odkaz:
https://doaj.org/article/b89f5358bb8b4ee09eef9e15269e454d
Autor:
Julie Bertrand, Aurélie Barrail-Tran, Lucie Fayette, Rada Savic, Cécile Goujard, Elina Teicher, Caroline Barau, Alain Pruvost, Anne-Marie Taburet, France Mentré, Céline Verstuyft, A. Barrail-Tran, A. Brunet, M.-J. Commoy, S. Couffin-Cadiergues, D. Descamps, X. Duval, C. Goujard, C. Le Guellec, F. Mentré, G. Nembot, A.-M. Taburet, B. Vrijens, •• Ajana, •• Aissi, •• Baclet, •• Besnier, •• Bollens, •• Boulanger, •• Brochier, •• Brunet, •• Chaix, •• Ciuchete, •• Ghosn, •• Duval, •• Ferret, •• Gaubin, •• Goujard, •• Girard, •• Kouadio, •• Lupin, •• Parienti, •• Parrinello, •• Poinçon de la Blanchardière, •• May, •• Marien, •• Medintzeff, •• Metivier, •• Mole, •• Molina, •• Nau, •• Ouazene, •• Pintado, •• Quertainmont, •• Ramani, •• Rami, •• Sellier, •• Simon, •• Talbi, •• Thoirain, •• Verdon, •• Trépo, •• Wassoumbou, •• Yazdanpanah, •• Barrail-Tran, •• Gagneux, •• Delhotal, •• Hoizey, •• Houdret, •• Leguellec, •• Peytavin, •• Poirier, •• Sauvageon, •• Taburet, •• André, •• Soulié, •• Calvez, •• Morand-Joubert, •• Harchi, •• Bocket, •• Mourez, •• Palmer, •• Pallier, •• Deschamps, •• Mazeron, •• Bolmann, •• Storto, •• Thanh Thuy, G. Unal, X. Panhard, R. Savic
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Tenofovir (TFV) and emtricitabine (FTC) are part of the recommended highly active antiretroviral therapy (ART). Both molecules show a large interindividual pharmacokinetic (PK) variability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79edc80bf1b79fa9ec9c15a7af7db223
https://doi.org/10.1128/aac.02339-18
https://doi.org/10.1128/aac.02339-18
Autor:
Asier Saez-Cirion, Caroline Passaes, Delphine Desjardins, Anais Chapel, Valérie Monceaux, Julien Lemaitre, Adeline Melard, Veronique Avettand-Fenoel, Federico Perdomo-Celis, Michaela Müller-Trutwin, Hugo Mouquet, Cyril Planchais, Annie David, Roger Le Grand, Nastasia Dimant, Nathalie Bosquet, Aurélie Barrail-Tran, Hélène Gouget, Céline Guillaume, Francis Relouzat, Olivier Lambotte, Jeremie Guedj, Christine Rouzioux
Post-treatment HIV controllers (PTCs) offer evidence that HIV remission can be achieved in some people after antiretroviral treatment (ART) discontinuation. However, the circumstances and mechanisms leading to PTC remain unclear. We evaluated the imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470e372369fcc8b6c2f8fadd7d2bcf6f
https://doi.org/10.21203/rs.3.rs-2777698/v1
https://doi.org/10.21203/rs.3.rs-2777698/v1
Autor:
Laura Labarthe, Thibaut Gelé, Hélène Gouget, Mariam-Sarah Benzemrane, Pauline Le Calvez, Nicolas Legrand, Olivier Lambotte, Roger Le Grand, Christine Bourgeois, Aurélie Barrail-Tran
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1094-1101
Background Studies of antiretroviral drug (ARV) tissue distribution in preclinical models, such as mice, are key to understanding viral persistence. Objectives To determine the plasma and tissue pharmacokinetics and tissue distributions of tenofovir,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d5ba552d42a8568b1b5d2c3170d888
https://doi.org/10.1093/jac/dkab501
https://doi.org/10.1093/jac/dkab501