Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aurélie Ayme"'
Autor:
Noémie Lang, Aurélie Ayme, Chang Ming, Jean‑Damien Combes, Victor N. Chappuis, Alex Friedlaender, Aurélie Vuilleumier, José L. Sandoval, Valeria Viassolo, Pierre O. Chappuis, S. Intidhar Labidi-Galy
Publikováno v:
Swiss Medical Weekly, Vol 153, Iss 3 (2023)
BACKGROUND: Carriers of germline pathogenic variants of the BRCA1 gene (gBRCA1) tend to have a higher incidence of haematological toxicity upon exposure to chemotherapy. We hypothesised that the occurrence of agranulocytosis during the first cycle of
Externí odkaz:
https://doaj.org/article/a8d8b33de2604ce9bbe07b894668f5ab
Autor:
Ketty Hu-Heimgartner, Noémie Lang, Aurélie Ayme, Chang Ming, Jean‑Damien Combes, Victor N. Chappuis, Carla Vazquez, Alex Friedlaender, Aurélie Vuilleumier, Alexandre Bodmer, Valeria Viassolo, José L Sandoval, Pierre O. Chappuis, S. Intidhar Labidi-Galy
Publikováno v:
Familial Cancer.
BRCA1 and BRCA2 play a central role in DNA repair and their germline pathogenic variants (gBRCA) confer a high risk for developing breast and ovarian cancer. Standard chemotherapy regimens for these cancers include DNA-damaging agents. We hypothesize
Autor:
Isabelle Ray-Coquard, Valérie Bonadona, Lisa Golmard, Adrien Buisson, Dominique Stoppa-Lyonnet, Claude Houdayer, Marc-Henri Stern, Pierre O. Chappuis, Aurélie Ayme, Valeria Viassolo, Patrick Meraldi, Pierre Meeus, Sarah Stuckelberger, Pierre-Etienne Heudel, Olivier Tredan, Nicolas Chopin, Beata Rak, Patrick Petignat, Alexandre Bodmer, Olfa Derbel, Domenico Ferraioli, Manuel Rodrigues, Timothée Olivier, S. Intidhar Labidi-Galy
Purpose: BRCA2 plays a central role in homologous recombination by loading RAD51 on DNA breaks. The objective of this study is to determine whether the location of mutations in the RAD51-binding domain (RAD51-BD; exon 11) of BRCA2 gene affects the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4eb9ceabf1b54d59749c3ad8240285
https://doi.org/10.1158/1078-0432.c.6526167.v1
https://doi.org/10.1158/1078-0432.c.6526167.v1
Autor:
Isabelle Ray-Coquard, Valérie Bonadona, Lisa Golmard, Adrien Buisson, Dominique Stoppa-Lyonnet, Claude Houdayer, Marc-Henri Stern, Pierre O. Chappuis, Aurélie Ayme, Valeria Viassolo, Patrick Meraldi, Pierre Meeus, Sarah Stuckelberger, Pierre-Etienne Heudel, Olivier Tredan, Nicolas Chopin, Beata Rak, Patrick Petignat, Alexandre Bodmer, Olfa Derbel, Domenico Ferraioli, Manuel Rodrigues, Timothée Olivier, S. Intidhar Labidi-Galy
Table S1: Multivariate Model of progression-free survival in the study cohort; Table S2: Multivariate Model of overall survival in the study cohort; Table S3: BRCA2 mutations in the study cohort; Figure S1: Flow diagram for selection of patients in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b6c8b7cf4cf27effb0bc72888b7d03
https://doi.org/10.1158/1078-0432.22465854
https://doi.org/10.1158/1078-0432.22465854
Autor:
Sophie Giraud, Noemie Lang, Solene De Talhouet, Adrien Buisson, Valeria Viassolo, S. Intidhar Labidi-Galy, Valérie Bonadona, Alexandre Bodmer, Aurélie Ayme, Alex Friedlaender, Jean-Christophe Tille, Aurelie Vuilleumier, Christine Lasset, Pierre O. Chappuis, Olivier Tredan, Isabelle Treilleux, Julien Péron
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports, Vol. 10, No 1 (2020) P. 7073
Scientific Reports
Scientific Reports, Vol. 10, No 1 (2020) P. 7073
BRCA1/BRCA2 genes play a central role in DNA repair and their mutations increase sensitivity to DNA-damaging agents. There are conflicting data regarding the prognostic value of BRCA germline mutations in breast cancer (BC) patients. We collected cli
Autor:
Viviane Cina, Marie Met-Domestici, Emeline Davoine, Aurélie Ayme, Céline Brockmann, Christophe Cordier, Anne Murphy
Publikováno v:
Revue Médicale Suisse. 15:1291-1293
Autor:
Aurélie Ayme, Jean-Christophe Tille, Noemie Lang, Alexandre Bodmer, Julien Péron, Sophie Giraud, Alex Friedlaender, Isabelle Treilleux, Adrien Buisson, Valérie Bonadona, Valeria Viassolo, Solene De Talhouet, Olivier Tredan, Pierre O. Chappuis, S. Intidhar Labidi-Galy, Christine Lasset, Aurelie Vuilleumier
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Julien Péron, Alexandre Bodmer, Isabelle Gauchat-Bouchardy, Jean-Damien Combes, Adrien Buisson, Olivier Tredan, Solene De Talhouet, Pierre O. Chappuis, Aurélie Ayme, Valeria Viassolo, Sophie Giraud, Aurelie Vuilleumier, Alex Friedlaender, S. Intidhar Labidi-Galy, Valérie Bonadona
Publikováno v:
Breast Cancer Research and Treatment, Vol. 174, No 3 (2019) pp. 775-783
BRCA1 and BRCA2 proteins are central to DNA repair process through homologous recombination. We hypothesize that BRCA1/BRCA2 mutation carriers may exhibit increased hematological toxicity when receiving genotoxic chemotherapy. We included women with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70135460a9cba36fecbf4a0037b5032
https://archive-ouverte.unige.ch/unige:120074
https://archive-ouverte.unige.ch/unige:120074
Publikováno v:
Imagerie de la Femme. 26:95-104
Resume Cinq a 10 % des cancers du sein s’inscrivent dans un contexte de predispositions genetiques hereditaires. Les principaux genes responsables sont BRCA1 et BRCA2 . La validite et l’utilite cliniques de l’identification de variants pathogen
Autor:
Olfa Derbel, Timothée Olivier, S. Intidhar Labidi-Galy, Nicolas Chopin, Valeria Viassolo, Manuel Rodrigues, Adrien Buisson, Valérie Bonadona, Marc-Henri Stern, Claude Houdayer, Pierre O. Chappuis, Sarah Stuckelberger, Domenico Ferraioli, Aurélie Ayme, Pierre-Etienne Heudel, Olivier Tredan, Lisa Golmard, Dominique Stoppa-Lyonnet, Alexandre Bodmer, Patrick Meraldi, Pierre Meeus, Beata Krystyna Rak, Isabelle Ray-Coquard, Patrick Petignat
Publikováno v:
Clinical Cancer Research, Vol. 24, No 2 (2018) pp. 326-333
Purpose: BRCA2 plays a central role in homologous recombination by loading RAD51 on DNA breaks. The objective of this study is to determine whether the location of mutations in the RAD51-binding domain (RAD51-BD; exon 11) of BRCA2 gene affects the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a367c9e8a4fec9afafdbaa3cf2981f00
https://archive-ouverte.unige.ch/unige:107105
https://archive-ouverte.unige.ch/unige:107105