Massive detection of cryptic recessive genetic defects in dairy cattle mining millions of life histories

Autor: Florian Besnard, Ana Guintard, Cécile Grohs, Laurence Guzylack-Piriou, Margarita Cano, Clémentine Escouflaire, Chris Hozé, Hélène Leclerc, Thierry Buronfosse, Lucie Dutheil, Jeanlin Jourdain, Anne Barbat, Sébastien Fritz, Marie-Christine Deloche, Aude Remot, Blandine Gaussères, Adèle Clément, Marion Bouchier, Elise Contat, Anne Relun, Vincent Plassard, Julie Rivière, Christine Péchoux, Marthe Vilotte, Camille Eche, Claire Kuchly, Mathieu Charles, Arnaud Boulling, Guillaume Viard, Stéphanie Minéry, Sarah Barbey, Clément Birbes, Coralie Danchin-Burge, Frédéric Launay, Sophie Mattalia, Aurélie Allais-Bonnet, Bérangère Ravary, Yves Millemann, Raphaël Guatteo, Christophe Klopp, Christine Gaspin, Carole Iampietro, Cécile Donnadieu, Denis Milan, Marie-Anne Arcangioli, Mekki Boussaha, Gilles Foucras, Didier Boichard, Aurélien Capitan

Publikováno v: Genome Biology, Vol 25, Iss 1, Pp 1-30 (2024)

Abstract Background Dairy cattle breeds are populations of limited effective size, subject to recurrent outbreaks of recessive defects that are commonly studied using positional cloning. However, this strategy, based on the observation of animals wit

Externí odkaz: https://doaj.org/article/c9ab6389eccd4e278eb6ccb394cbc8f9

Novel insights into the bovine polled phenotype and horn ontogenesis in Bovidae.

Autor: Aurélie Allais-Bonnet, Cécile Grohs, Ivica Medugorac, Stefan Krebs, Anis Djari, Alexander Graf, Sébastien Fritz, Doris Seichter, Aurélia Baur, Ingolf Russ, Stéphan Bouet, Sophie Rothammer, Per Wahlberg, Diane Esquerré, Chris Hoze, Mekki Boussaha, Bernard Weiss, Dominique Thépot, Marie-Noëlle Fouilloux, Marie-Noëlle Rossignol, Este van Marle-Köster, Gunnfríður Elín Hreiðarsdóttir, Sarah Barbey, Dominique Dozias, Emilie Cobo, Patrick Reversé, Olivier Catros, Jean-Luc Marchand, Pascal Soulas, Pierre Roy, Brigitte Marquant-Leguienne, Daniel Le Bourhis, Laetitia Clément, Laura Salas-Cortes, Eric Venot, Maëlle Pannetier, Florence Phocas, Christophe Klopp, Dominique Rocha, Michel Fouchet, Laurent Journaux, Carine Bernard-Capel, Claire Ponsart, André Eggen, Helmut Blum, Yves Gallard, Didier Boichard, Eric Pailhoux, Aurélien Capitan

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63512 (2013)

Despite massive research efforts, the molecular etiology of bovine polledness and the developmental pathways involved in horn ontogenesis are still poorly understood. In a recent article, we provided evidence for the existence of at least two differe

Externí odkaz: https://doaj.org/article/f085e21b9eb648f68096624ff77990e5

Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

Autor: Daniele Bigi, Fiona Menzi, Slim Ben Jemaa, Marie-Christine Deloche, Aurélien Capitan, Johannes A. Lenstra, Marina Naval-Sanchez, Ivica Medugorac, Nathalie Hirter, Gwenola Tosser-Klopp, Diane Esquerre, Coralie M. Reich, Julia M. Paris, Rose-Marie Arbogast, Amandine Blin, Abdelhak Boukadiri, Aurélie Hintermann, Julie Rivière, Denis Duboule, Raphaël Cornette, Cécile Donnadieu, Marie-Dominique Wandhammer, Gjoko Bunevski, Louisa Gidney, Michael Stache, Isabelle Palhiere, Renate Schafberg, James Kijas, Claude Guintard, Joséphine Lesur, Jozsef Zakany, Rachel Rupp, Noelle E. Cockett, John Hedges, Ashleigh Haruda, Philippe Bardou, Olivier Putelat, Tracy Hadfield, Alain Pinton, Ockert Greyvenstein, Aurélie Allais-Bonnet, Este Van Marle-Koster, Eric Pailhoux, Coralie Danchin-Burge, David G. Riley, Cécile Grohs, Benjamin J. Hayes, Cord Drögemüller

Publikováno v: Molecular Biology and Evolution
Molecular Biology and Evolution, Oxford University Press (OUP), 2021, ⟨10.1093/molbev/msab021⟩
Allais-Bonnet, Aurélie; Hintermann, Aurélie; Deloche, Marie-Christine; Cornette, Raphaël; Bardou, Philippe; Naval-Sanchez, Marina; Pinton, Alain; Haruda, Ashleigh; Grohs, Cécile; Zakany, Jozsef; Bigi, Daniele; Medugorac, Ivica; Putelat, Olivier; Greyvenstein, Ockert; Hadfield, Tracy; Jemaa, Slim Ben; Bunevski, Gjoko; Menzi, Fiona; Hirter, Nathalie; Paris, Julia M; ... (2021). Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae. Molecular Biology and Evolution, 38(6), pp. 2260-2272. Oxford University Press 10.1093/molbev/msab021
Molecular Biology and Evolution, 2021, ⟨10.1093/molbev/msab021⟩
Molecular Biology and Evolution, 38(6), 2260. Oxford University Press

In the course of evolution, pecorans (i.e., higher ruminants) developed a remarkable diversity of osseous cranial appendages, collectively referred to as “headgear,” which likely share the same origin and genetic basis. However, the nature and fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e81f9ba5bd3ae8e59d2ce96dcb31adc
https://hal.archives-ouvertes.fr/hal-03164832/file/msab021.pdf

Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis

Autor: Maëva Elzaiat, Luc Jouneau, Aurélie Allais-Bonnet, Eric Pailhoux, Marjolaine André, Ikrame Naciri, Eli Sellem, Bruno Passet, Nicolas Meunier, Clara Gobe, Maëlle Pannetier, Patrice Congar

Publikováno v: PLoS Genetics
PLoS Genetics, Public Library of Science, 2019, 15 (2), pp.1-28. ⟨10.1371/journal.pgen.1007909⟩
Plos Genetics 2 (15), 1-28. (2019)
PLoS Genetics, Vol 15, Iss 2, p e1007909 (2019)

Gonad differentiation is a crucial step conditioning the future fertility of individuals and most of the master genes involved in this process have been investigated in detail. However, transcriptomic analyses of developing gonads from different anim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07632f2f787007fb732b6df794205945
https://hal.inrae.fr/hal-02622530

An initiator codon mutation in SDE2 causes recessive embryonic lethality in Holstein cattle

Autor: Maëlle Philippe, Y. Amigues, Aurélie Allais-Bonnet, Mekki Boussaha, Clémentine Escouflaire, Cécile Grohs, Christy J. Vander Jagt, Benjamin J. Hayes, Anne Barbat, Amanda J. Chamberlain, Didier Boichard, Amélie Vallée, Emmanuelle Rebours, Aurélien Capitan, Méline Bizard, Chris Hozé, Sébastien Fritz

Publikováno v: Journal of Dairy Science
Journal of Dairy Science, American Dairy Science Association, 2018, 101 (7), pp.6220-6231. ⟨10.3168/jds.2017-14119⟩

International audience; Researching depletions in homozygous genotypes for specific haplotypes among the large cohorts of animals genotyped for genomic selection is a very efficient strategy to map recessive lethal mutations. In this study, by analyz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23aedb3b1235a2f53d30b5a6c24574ea
https://hal.inrae.fr/hal-02623515