Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Aurélie, Morin"'
Autor:
Anne Fajac, Iva Simeonova, Julia Leemput, Marc Gabriel, Aurélie Morin, Vincent Lejour, Annaïg Hamon, Jeanne Rakotopare, Wilhelm Vaysse-Zinkhöfer, Eliana Eldawra, Marina Pinskaya, Antonin Morillon, Jean-Christophe Bourdon, Boris Bardot, Franck Toledo
Publikováno v:
eLife, Vol 13 (2024)
The Trp53 gene encodes several isoforms of elusive biological significance. Here, we show that mice lacking the Trp53 alternatively spliced (AS) exon, thereby expressing the canonical p53 protein but not isoforms with the AS C-terminus, have unexpect
Externí odkaz:
https://doaj.org/article/24d352706ace432cafb1b14b25ca0b61
Autor:
Álvaro Javier Feliz Morel, Anida Hasanovic, Aurélie Morin, Chloé Prunier, Virginie Magnone, Kevin Lebrigand, Amaury Aouad, Sarah Cogoluegnes, Judith Favier, Claude Pasquier, Isabelle Mus-Veteau
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 988 (2022)
Despite the development of new therapeutic strategies, cancer remains one of the leading causes of mortality worldwide. One of the current major challenges is the resistance of cancers to chemotherapy treatments inducing metastases and relapse of the
Externí odkaz:
https://doaj.org/article/80ace4a621564498b21bec9f6d15b51a
Autor:
Judith Favier, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Chris Ottolenghi, Laurence Amar, Jérôme Bertherat, Lucien Tchara, Thi Tran, Mathilde Padilla-Girola, Isabelle Raingeard, Magalie Haissaguerre, Isabelle Guilhem, Hervé Lefebvre, Eric Letouzé, Charlotte Lussey-Lepoutre, Florence Habarou, Luis-Jaime Castro-Vega, Aurélie Morin, Alexandre Buffet
Supplementary Methods Supplementary Clinics Figures S1 to S9 Tables S1 to S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0911baedb044c4d4cb0d14a81808da75
https://doi.org/10.1158/0008-5472.22418310
https://doi.org/10.1158/0008-5472.22418310
Autor:
Judith Favier, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Chris Ottolenghi, Laurence Amar, Jérôme Bertherat, Lucien Tchara, Thi Tran, Mathilde Padilla-Girola, Isabelle Raingeard, Magalie Haissaguerre, Isabelle Guilhem, Hervé Lefebvre, Eric Letouzé, Charlotte Lussey-Lepoutre, Florence Habarou, Luis-Jaime Castro-Vega, Aurélie Morin, Alexandre Buffet
Supplementary Table S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad8603de9b50e5eb49f55f878f9024d
https://doi.org/10.1158/0008-5472.22418313.v1
https://doi.org/10.1158/0008-5472.22418313.v1
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Succinate dehydrogenase is a key enzyme in the tricarboxylic acid cycle and the electron transport chain. All four subunits of succinate dehydrogenase are tumor suppressor genes predisposing to paraganglioma, but only mutations in the SDHB subunit ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8344fed531abd70c4e2067dd3f8dac8
https://doi.org/10.1158/0008-5472.c.6513153.v1
https://doi.org/10.1158/0008-5472.c.6513153.v1
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Supplementary Figure 1 - Supplementary Figure 2 - Supplementary Figure 3 - Supplementary Figure 4 - Supplementary Figure 5 - Supplementary Figure 6 - Supplementary Table 1 - Supplementary Table 2 - Supplementary Table 3 - Supplementary Table 4 - Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fa5c66a17bcd42509bb7c99b59f814
https://doi.org/10.1158/0008-5472.22428819
https://doi.org/10.1158/0008-5472.22428819
Autor:
Bertrand Tavitian, Judith Favier, Anne-Paule Gimenez-Roqueplo, Laure Fournier, Philippe Halimi, Pierre Rustin, Paule Benit, Charles-André Cuenod, Sébastien Fontaine, Benjamin Banting, Estelle Robidel, Nelly Burnichon, Gwennhael Autret, Franck Zinzindohoué, Chris Ottolenghi, Maxime Janin, Laurence Amar, Alexandre Buffet, Aurélie Morin, Alexandre Bellucci, Charlotte Lussey-Lepoutre
Purpose: Germline mutations in genes encoding mitochondrial succinate dehydrogenase (SDH) are found in patients with paragangliomas, pheochromocytomas, gastrointestinal stromal tumors, and renal cancers. SDH inactivation leads to a massive accumulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8cd277de82a1e9a730d96603b9dd34
https://doi.org/10.1158/1078-0432.c.6523461.v1
https://doi.org/10.1158/1078-0432.c.6523461.v1
Autor:
Judith Favier, Daniel A. Tennant, Eric Letouzé, Anne-Paule Gimenez-Roqueplo, Fatima Mechta-Grigoriou, Raphaël Rodriguez, Jennie Roberts, Lisa Vettore, Alpesh Thakker, Paule Bénit, Charlotte Lussey-Lepoutre, Cynthia L. Andoniadou, Theodora J. Stewart, Katarina Kluckova, Alexander P. Morrell, Sebastian Müller, Géraldine Gentric, Aurélie Morin, Sophie Moog, Judith Goncalves
Supplementary Table 2 Related to Figure 2. Differentially methylated gene-based features in Sdhb-/- versus Sdhd-/- imCCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b04c08f42c8e0660b2c6f91c099c84
https://doi.org/10.1158/0008-5472.22428816.v1
https://doi.org/10.1158/0008-5472.22428816.v1
Autor:
Judith Favier, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Chris Ottolenghi, Laurence Amar, Jérôme Bertherat, Lucien Tchara, Thi Tran, Mathilde Padilla-Girola, Isabelle Raingeard, Magalie Haissaguerre, Isabelle Guilhem, Hervé Lefebvre, Eric Letouzé, Charlotte Lussey-Lepoutre, Florence Habarou, Luis-Jaime Castro-Vega, Aurélie Morin, Alexandre Buffet
Comprehensive genetic analyses have identified germline SDHB and FH gene mutations as predominant causes of metastatic paraganglioma and pheochromocytoma. However, some suspicious cases remain unexplained. In this study, we performed whole-exome sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a7e3fcc4bc1e064d545efca3806094
https://doi.org/10.1158/0008-5472.c.6510093.v1
https://doi.org/10.1158/0008-5472.c.6510093.v1
Autor:
Bertrand Tavitian, Judith Favier, Anne-Paule Gimenez-Roqueplo, Laure Fournier, Philippe Halimi, Pierre Rustin, Paule Benit, Charles-André Cuenod, Sébastien Fontaine, Benjamin Banting, Estelle Robidel, Nelly Burnichon, Gwennhael Autret, Franck Zinzindohoué, Chris Ottolenghi, Maxime Janin, Laurence Amar, Alexandre Buffet, Aurélie Morin, Alexandre Bellucci, Charlotte Lussey-Lepoutre
Figure S1- Phantom spectra of succinate at 4.7T and 3 T. Figure S2- SUCCES in Sdhb-/- allografted tumors in mice. Figure S3 - SUCCES in SDHx-mutated PPGL. Figure S4 - SUCCES in non SDHx-mutated PPGL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d12bb255471bddd7c9e05a14c63e26
https://doi.org/10.1158/1078-0432.22456938
https://doi.org/10.1158/1078-0432.22456938