Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aurélie, Candi"'
Autor:
Lei Chen, Paula Milani de Marval, Kendall Powell, Mark Johnson, Greg Falls, Brian Lawhorn, Aurélie Candi, Amuri Kilonda, Bart Vanderhoydonck, Arnaud Marchand, Matthias Versele, Georg Halder, Stephen L. Gwaltney, Adeela Kamal
Publikováno v:
Cancer Research. 83:4964-4964
Many cancers harbor mutations in the Hippo pathway that lead to constitutive activation of the transcriptional co-activators YAP/TAZ that then bind the transcription factor TEAD and drive aberrant transcription of target genes involved in cell prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff72fff7f3b3f1feb5934f47b68973aa
https://doi.org/10.1158/1538-7445.am2023-4964
https://doi.org/10.1158/1538-7445.am2023-4964
Autor:
Adeela Kamal, Aurélie Candi, Matthias Versele, Bart Vanderhoydonck, Arnaud Marchand, Ron de Jong, Thuy Hoang, Georg Halder, Patrick Chaltin, Stephen L. Gwaltney, Mike Burgess
Publikováno v:
Cancer Research. 82:3945-3945
Background: The Hippo pathway is an evolutionarily conserved signaling cascade whose deregulation can promote excessive cell proliferation and tumor development. Pathway output is mediated by the YAP and TAZ transcriptional co-activators, which bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4509ba65fd9177d8f75b5e6f63729b
https://doi.org/10.1158/1538-7445.am2022-3945
https://doi.org/10.1158/1538-7445.am2022-3945
Autor:
Leticia Sansores, Matthias Versele, Bart Vanderhoydonck, Wim Smets, Aurélie Candi, Arnaud Marchand, Wanda Haeck, Marnik Nijs, Patrick Chaltin, Georg Halder, Stéphane Spieser, Hugo Klaassen
Publikováno v:
Cancer Research. 80:5229-5229
The Hippo pathway is a highly conserved signaling pathway across higher-order vertebrates and a key modulator of developmental biology. Both genetic aberrations as well as non-genetic dysregulation of the pathway lead to constitutive nuclear localiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62badb1cf6daa846dd8476b80c4ab733
https://doi.org/10.1158/1538-7445.am2020-5229
https://doi.org/10.1158/1538-7445.am2020-5229
Autor:
Bart Jonckx, Michaël Porcu, Philippe Barbeaux, Isabelle Etienne, Jean H.M. Feyen, Aurélie Candi
Publikováno v:
Journal of Ophthalmology, Vol 2017 (2017)
Journal of Ophthalmology
Journal of Ophthalmology
Ocriplasmin (Jetrea®) is a recombinant protease used to treat vitreomacular traction. To gain insight into vitreoretinal observations reported after ocriplasmin treatment, we have developed anin vivoporcine ocriplasmin-induced posterior vitreous det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69518805b250922ed34bda04d6e9e5af
Autor:
Aurélie Candi, Peter Carmeliet, Steven Goossens, Benjamin Beck, Guilhem Mascré, Amélie Caauwe, Panagiota A. Sotiropoulou, Anna Kuchnio, Benjamin Drogat, Gaëlle Lapouge, Khalil Kass Youssef, Cédric Blanpain, Jody J. Haigh, Gregory Driessens, Sophie Dekoninck, Sonja Loges
Publikováno v:
Nature. 478:399-403
Angiogenesis is critical during tumour initiation and malignant progression. Different strategies aimed at blocking vascular endothelial growth factor (VEGF) and its receptors have been developed to inhibit angiogenesis in cancer patients. It has bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb6edbfde3fcbf02919feeaa1c64e05
https://doi.org/10.1038/nature10525
https://doi.org/10.1038/nature10525
Autor:
Carine Munaut, Karim Zouaoui Boudjeltia, Marie-Rose Pignon, Hidde Bult, Martine Raes, Martine Vansteenbrugge, Sofia Dos Santos Mendes, Aurélie Candi
Publikováno v:
Cellular Signalling. 21:1109-1122
Lipopolysaccharide (LPS) activates a broad range of signalling pathways including mainly NF-kappaB and the MAPK cascade, but recent evidence suggests that LPS stimulation also activates the PI3K pathway. To unravel the specific roles of both pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19455ab2c910112bf5d31dace7df366e
https://doi.org/10.1016/j.cellsig.2009.02.025
https://doi.org/10.1016/j.cellsig.2009.02.025
Publikováno v:
Stem Cells. 26:2964-2973
The maintenance of genome integrity in stem cells (SCs) is critical for preventing cancer formation and cellular senescence. The immortal strand hypothesis postulates that SCs protect their genome by keeping the same DNA strand throughout life by asy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c6a55c345d37a04f9d97ab7e591d54
https://doi.org/10.1634/stemcells.2008-0634
https://doi.org/10.1634/stemcells.2008-0634
Autor:
Virginie Moers, Maud Debaugnies, Andrea E. Karambelas, Jos Jonkers, Kiyotoshi Sekiguchi, Cédric Blanpain, Peter Bouwman, Panagiota A. Sotiropoulou, Ana Rocha, Aurélie Candi, Tatiana Revenco
Panagiota A. Sotiropoulou, Andrea E. Karambelas, Maud Debaugnies, Aurelie Candi, Peter Bouwman, Virginie Moers, Tatiana Revenco, Ana Sofia Rocha, Kiyotoshi Sekiguchi, Jos Jonkers and Cedric Blanpain, "BRCA1 deficiency in skin epidermis leads to selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93ab974b46c74e37186a424878c9d4b
https://europepmc.org/articles/PMC3553282/
https://europepmc.org/articles/PMC3553282/
Autor:
Claudio Semeraro, Guilhem Mascré, Sarah De Clercq, Jean-Christophe Marine, Cédric Blanpain, Ellen Dahl, Gaëlle Lapouge, Khalil Kass Youssef, Panagiota A. Sotiropoulou, Geertrui Denecker, Aurélie Candi
Publikováno v:
Nature cell biology. 12(6)
Adult stem cells (SCs) are at high risk of accumulating deleterious mutations because they reside and self-renew in adult tissues for extended periods. Little is known about how adult SCs sense and respond to DNA damage within their natural niche. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c083ebe409ef5c4cf201bfbaccd1af1b
https://pubmed.ncbi.nlm.nih.gov/20531424
https://pubmed.ncbi.nlm.nih.gov/20531424
Autor:
Sofia Dos Santos, Mendes, Aurélie, Candi, Martine, Vansteenbrugge, Marie-Rose, Pignon, Hidde, Bult, Karim Zouaoui, Boudjeltia, Carine, Munaut, Martine, Raes
Publikováno v:
Cellular signalling. 21(7)
Lipopolysaccharide (LPS) activates a broad range of signalling pathways including mainly NF-kappaB and the MAPK cascade, but recent evidence suggests that LPS stimulation also activates the PI3K pathway. To unravel the specific roles of both pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92b438a0f5047ae49119511ca2184953
https://pubmed.ncbi.nlm.nih.gov/19285553
https://pubmed.ncbi.nlm.nih.gov/19285553