Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Aurélia Defour"'
Autor:
Aurélia Defour, Kevin Dessalle, Andréa Castro Perez, Thomas Poyot, Josiane Castells, Yann Simon Gallot, Christine Durand, Vanessa Euthine, Yansong Gu, Daniel Béchet, André Peinnequin, Etienne Lefai, Damien Freyssenet
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43490 (2012)
Sirtuin 1 (SIRT1), a NAD(+)-dependent protein deacetylase, has emerged as a main determinant of whole body homeostasis in mammals by regulating a large spectrum of transcriptional regulators in metabolically relevant tissue such as liver, adipose tis
Externí odkaz:
https://doaj.org/article/d47d264a9a824503b1bd5b9c2a6e8300
Autor:
Vanessa E Jahnke, Odile Sabido, Aurélia Defour, Josiane Castells, Etienne Lefai, Damien Roussel, Damien Freyssenet
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8637 (2010)
BACKGROUND: Mitochondria can sense signals linked to variations in energy demand to regulate nuclear gene expression. This retrograde signaling pathway is presumed to be involved in the regulation of myoblast proliferation and differentiation. Rhabdo
Externí odkaz:
https://doaj.org/article/ebe4b126e046445cae420332673cd575
Autor:
Vanessa E. Jahnke, Jennifer M. Peterson, Jack H. Van Der Meulen, Jessica Boehler, Kitipong Uaesoontrachoon, Helen K. Johnston, Aurelia Defour, Aditi Phadke, Qing Yu, Jyoti K. Jaiswal, Kanneboyina Nagaraju
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Background Nonsense or loss-of-function mutations in the non-lysosomal cysteine protease calpain-3 result in limb-girdle muscular dystrophy type 2A (LGMD2A). While calpain-3 is implicated in muscle cell differentiation, sarcomere formation,
Externí odkaz:
https://doaj.org/article/050731eeba884453b57d2710d7a8e532
Autor:
Marshall W. Hogarth, Aurelia Defour, Christopher Lazarski, Eduard Gallardo, Jordi Diaz Manera, Terence A. Partridge, Kanneboyina Nagaraju, Jyoti K. Jaiswal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Fibroadipogenic precursor cells (FAPs) contribute to fibrosis and adipogenic replacement in muscular dystrophies. Here, the authors show that FAPs contribute to adipogenic loss in mouse models of limb girdle muscular dystrophy 2B via a mechanism depe
Externí odkaz:
https://doaj.org/article/0de39a40d2af49bb9bb31819d111a9f9
Autor:
Daniel C. Bittel, Goutam Chandra, Laxmi M. S. Tirunagri, Arun B. Deora, Sushma Medikayala, Luana Scheffer, Aurelia Defour, Jyoti K. Jaiswal
Publikováno v:
Cells, Vol 9, Iss 9, p 1919 (2020)
Muscle cell plasma membrane is frequently damaged by mechanical activity, and its repair requires the membrane protein dysferlin. We previously identified that, similar to dysferlin deficit, lack of annexin A2 (AnxA2) also impairs repair of skeletal
Externí odkaz:
https://doaj.org/article/2f042f974983491595d999e7337b246d