Výsledky vyhledávání - "Aurélia, Hiron"

Akademický článek

Identification of Zinc-Dependent Mechanisms Used by Group B Streptococcus To Overcome Calprotectin-Mediated Stress

Autor: Lindsey R. Burcham, Yoann Le Breton, Jana N. Radin, Brady L. Spencer, Liwen Deng, Aurélia Hiron, Monica R. Ransom, Jéssica da C. Mendonça, Ashton T. Belew, Najib M. El-Sayed, Kevin S. McIver, Thomas E. Kehl-Fie, Kelly S. Doran

Publikováno v: mBio, Vol 11, Iss 6 (2020)

ABSTRACT Nutritional immunity is an elegant host mechanism used to starve invading pathogens of necessary nutrient metals. Calprotectin, a metal-binding protein, is produced abundantly by neutrophils and is found in high concentrations within inflamm

Externí odkaz: https://doaj.org/article/d67d2f2522254a81b3f4b51a434b7931

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Streptococcus agalactiae imports spermidine by a member of the amino acid/polyamine antiporter family to endure citric acid stress at the vaginal pH

Autor: Sarah Khazaal, Rim Al Safadi, Dani Osman, Aurélia Hiron, Philippe Gilot

Publikováno v: Microbiology. 168

Polyamines bind to various cellular components, such as nucleic acids, phospholipids, proteins and nucleotides. They are involved in the virulence and protection against physiological stresses of several bacterial species. Streptococcus agalactiae is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aca47e010fb66f0a2547893833445e84
https://doi.org/10.1099/mic.0.001219

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Investigation of the polyamine biosynthetic and transport capability of

Autor: Sarah, Khazaal, Rim, Al Safadi, Dani, Osman, Aurélia, Hiron, Philippe, Gilot

Publikováno v: Microbiology

Polyamines constitute a group of organic polycations positively charged at physiological pH. They are involved in a large variety of biological processes, including the protection against physiological stress. In this study, we show that the genome o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3ee529dc9ca8192ddba0bc0afb5018c
https://pubmed.ncbi.nlm.nih.gov/34910617

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Identification of Zinc-Dependent Mechanisms Used by Group B Streptococcus To Overcome Calprotectin-Mediated Stress

Autor: Monica Ransom, Kelly S. Doran, Jana N. Radin, Kevin S. McIver, Najib M. El-Sayed, Liwen Deng, Ashton T. Belew, Thomas E. Kehl-Fie, Yoann Le Breton, Lindsey R. Burcham, Brady L. Spencer, Jéssica da C. Mendonça, Aurélia Hiron

Publikováno v: mBio, Vol 11, Iss 6 (2020)
mBio
mBio, American Society for Microbiology, 2020, 11 (6), 18 p. ⟨10.1128/mBio.02302-20⟩
mBio, 2020, 11 (6), ⟨10.1128/mBio.02302-20⟩

Group B Streptococcus (GBS) asymptomatically colonizes the female reproductive tract but is a common causative agent of meningitis. GBS meningitis is characterized by extensive infiltration of neutrophils carrying high concentrations of calprotectin,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52b13af787b20634479f8ff85ccba73
https://journals.asm.org/doi/10.1128/mBio.02302-20

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Akademický článek

Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways.

Autor: Mélanie Falord, Ulrike Mäder, Aurélia Hiron, Michel Débarbouillé, Tarek Msadek

Publikováno v: PLoS ONE, Vol 6, Iss 7, p e21323 (2011)

The GraS/GraR two-component system has been shown to control cationic antimicrobial peptide (CAMP) resistance in the major human pathogen Staphylococcus aureus. We demonstrated that graX, also involved in CAMP resistance and cotranscribed with graRS,

Externí odkaz: https://doaj.org/article/770531a9df6a41de9490b97bb3a26d67

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Inductors and regulatory properties of the genomic island-associatedfru2metabolic operon ofStreptococcus agalactiae

Autor: Emilie Camiade, Vanessa Rong, Kévin Patron, Philippe Gilot, Laurent Mereghetti, Aurélia Hiron

Publikováno v: Molecular Microbiology. 103:678-697

The fru2 metabolic operon of Streptococcus agalactiae encodes the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) enzyme II complex Fru2 (EIIBFru2 , EIIAFru2 , and EIICFru2 ); Fru2 R, a transcriptional activator with PTS regulatory d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09a63a9bc09971e52dfb9ad5eb1eb559
https://doi.org/10.1111/mmi.13581

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Data on the link between genomic integration of IS

Autor: Sarah, Khazaal, Rim, Al Safadi, Dani, Osman, Aurélia, Hiron, Philippe, Gilot

Publikováno v: Data in Brief

IS1548, a 1316-bp element of the ISAs1 family affects the expression of several genes of the opportunistic pathogen Streptococcus agalactiae. Furthermore, certain lineages of S. agalactiae are more frequently associated to particular diseases than ot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38b29d078a48e55e75052b448c857482
https://pubmed.ncbi.nlm.nih.gov/32226814

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Srn024, un petit ARN nécessaire à la croissance bactérienne chez le pathogène Streptococcus agalactiae

Autor: Nancy Jabbour, Aurélia Hiron, Sophie Poussing, Marie-Frédérique Lartigue

Publikováno v: 15. Congrès National de la Société Française de Microbiologie (SFM)
15. Congrès National de la Société Française de Microbiologie (SFM), Société Française de Microbiologie (SFM). FRA., Sep 2019, Paris, France. pp.436
HAL
32ème Colloque Biotechnocentre
32ème Colloque Biotechnocentre, Oct 2019, Seillac, France. 2019

National audience; Introduction et objectif : Streptococcus agalactie est la cause majeure des infections néonatales humaines, mais aussi un pathogène émergent chez les adultes immunodéprimés. Sa capacité à coloniser différents hôtes montre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d756a460d4bc08ed9ad2579f050cca7
https://hal.inrae.fr/hal-02736789

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Dual and divergent transcriptional impact of IS1548 insertion upstream of the peptidoglycan biosynthesis gene murB of Streptococcus agalactiae

Autor: Sarah Khazaal, Rim Al Safadi, Dani Osman, Aurélia Hiron, Philippe Gilot

Publikováno v: Gene
Gene, Elsevier, 2019, 720, 10 p. ⟨10.1016/j.gene.2019.144094⟩

International audience; Fourteen different insertion sequences belonging to seven families were identified in the genome of Streptococcus agalactiae. Among them, IS1548, a mobile element of the ISAs1 family, was linked to clonal complex (CC) 19 strai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0676ef25c32c33940ec88823a1f81833
https://hal.inrae.fr/hal-02626494/file/S037811191930753X.pdf

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Defining the role of the Streptococcus agalactiae Sht-family proteins in zinc acquisition and complement evasion

Autor: Laurent Mereghetti, V. Rong, P. Moulin, Victoria G. Pederick, Christopher A. McDevitt, A. Ribeiro E Silva, Aurélia Hiron, Emilie Camiade

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2019, 201 (8), 16 p. ⟨10.1128/JB.00757-18⟩

International audience; Streptococcus agalactiae is part of the human intestinal and uro-genital microbiota, but also a leading cause of septicemia and meningitis in neonates. Its ability to cause disease depends upon the acquisition of nutrients fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296e17d32ae635659beb41e3b17b0c65
https://hal.inrae.fr/hal-02626937

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