Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aung Maung Maung Kyaw"'
Autor:
Diana Teh Chee Siang, Yen Ching Lim, Aung Maung Maung Kyaw, Khaing Nwe Win, Sook Yoong Chia, Ufuk Degirmenci, Xiang Hu, Bryan C. Tan, Arcinas Camille Esther Walet, Lei Sun, Dan Xu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Human antigen R (HuR) is an RNA binding protein that promotes mRNA stability. Here the authors show that HuR represses adipogenesis in white and brown adipose tissue by stabilizing Insig1 and other targets.
Externí odkaz:
https://doaj.org/article/d5a3ed7333c84e9d83c9d20cc549253a
Autor:
Bryan C. Tan, Sook Yoong Chia, Yen Ching Lim, Arcinas Camille Esther Walet, Ufuk Degirmenci, Diana Teh Chee Siang, Lei Sun, Khaing Nwe Win, Xiang Hu, Dan Xu, Aung Maung Maung Kyaw
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Human antigen R (HuR) is an essential regulator of RNA metabolism, but its function in metabolism remains unclear. This study identifies HuR as a major repressor during adipogenesis. Knockdown and overexpression of HuR in primary adipocyte culture en
Autor:
Dan Xu, Melvin Khee-Shing Leow, Lei Sun, Peng Chen, Yen Ching Lim, Juan R. Alvarez-Dominguez, Diana Teh Chee Siang, Aung Maung Maung Kyaw, Shaohai Xu, Sook Yoong Chia
Publikováno v:
Diabetes. 66(12)
Recent years have seen an upsurge of interest in brown adipose tissue (BAT) to combat the epidemic of obesity and diabetes. How its development and activation are regulated at the posttranscriptional level, however, has yet to be fully understood. RN