Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Aundrietta D. Duncan"'
Autor:
Daniela Santiesteban, Aundrietta D. Duncan, Nadeem Q. Mirza, Stephen Horrigan, Sheila Dewitt, Vincent Jacques, Swaminathan P. Iyer
Publikováno v:
HemaSphere, Vol 7, p e95971dd (2023)
Externí odkaz:
https://doaj.org/article/84cc5aa832f14e99bfcc36a5048a2ec2
Autor:
Vrutant V. Shah, Aundrietta D. Duncan, Shiming Jiang, Sabrina A. Stratton, Kendra L. Allton, Clinton Yam, Abhinav Jain, Patrick M. Krause, Yue Lu, Shirong Cai, Yizheng Tu, Xinhui Zhou, Xiaomei Zhang, Yan Jiang, Christopher L. Carroll, Zhijun Kang, Bin Liu, Jianjun Shen, Mihai Gagea, Sebastian M. Manu, Lei Huo, Michael Gilcrease, Reid T. Powell, Lei Guo, Clifford Stephan, Peter J. Davies, Jan Parker-Thornburg, Guillermina Lozano, Richard R. Behringer, Helen Piwnica-Worms, Jeffrey T. Chang, Stacy L. Moulder, Michelle Craig Barton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Human metaplastic breast cancers (MpBC) are a rare, aggressive subclass of triple-negative breast cancers. Here, the authors show over-expression of histone reader TRIM24 is sufficient to generate tumors with a molecular signature of metabolic dysfun
Externí odkaz:
https://doaj.org/article/d198e1ab2b18460f8fd9661445a6e392
Autor:
Lei Huo, Abhinav K. Jain, Christopher Carroll, Jan Parker-Thornburg, Guillermina Lozano, Shirong Cai, Sabrina A. Stratton, Mihai Gagea, Michelle Craig Barton, Yan Jiang, Clifford Stephan, Michael Z. Gilcrease, Xinhui Zhou, Patrick M. Krause, Vrutant Shah, Lei Guo, Xiaomei Zhang, Stacy L. Moulder, Shiming Jiang, Peter J.A. Davies, Aundrietta D. Duncan, Helen Piwnica-Worms, Jianjun Shen, Clinton Yam, Richard R. Behringer, Zhijun Kang, Reid T. Powell, Bin Liu, Kendra Allton, Yue Lu, Yizheng Tu, Sebastian M. Manu, Jeffrey T. Chang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Conditional overexpression of histone reader Tripartite motif containing protein 24 (TRIM24) in mouse mammary epithelia (Trim24COE) drives spontaneous development of mammary carcinosarcoma tumors, lacking ER, PR and HER2. Human carcinosarcomas or met
Autor:
Daniela Y Santiesteban, Aundrietta D Duncan, Nadeem Q Mirza, Vincent Jacques, Sheila DeWitt, Swami P. Iyer
Publikováno v:
Blood. 140:8865-8866
Autor:
Joe McDonough, G. Lesa, Franca Ligas, Miguel Rivera, Ira Jacobs, Andrew D.J. Pearson, Malcolm A. Smith, Maureen Hattersley, Dominik Karres, Aundrietta D. Duncan, Nada Jabado, Daniel D. De Carvalho, Koen Norga, Peter C. Adamson, Donna Ludwinski, Gregory H. Reaman, Brian Gadbaw, Elizabeth Fox, Samuel C. Blackman, Mark W. Kieran, Gilles Vassal, Christian Baumann, Vickie Buenger, Delphine Heenen, Scott A. Armstrong, Michael J. Kelly, Amy Barone, Adrian Senderowicz, Franck Bourdeaut, Martha Donoghue, Tilmann Taube, Peter T.C. Ho, Lynley V. Marshall, Patrick A. Brown, Michael L. Meyers, Kimberly Stegmaier, Zariana Nikolova, Susan L. Weiner
Publikováno v:
European Journal of Cancer. 139:135-148
The fifth multistakeholder Paediatric Strategy Forum focussed on epigenetic modifier therapies for children and adolescents with cancer. As most mutations in paediatric malignancies influence chromatin-associated proteins or transcription and paediat
Publikováno v:
Molecular Cancer Therapeutics. 20:P087-P087
The RNA-binding proteins, FUS, EWSR1, and TAF15 (FET protein family) are frequently fused to transcription factors, and the resulting oncogenic fusion proteins characterize various sarcomas. These fusion proteins act as aberrant transcription factors
Autor:
Andrew Dj, Pearson, Kimberly, Stegmaier, Franck, Bourdeaut, Gregory, Reaman, Delphine, Heenen, Michael L, Meyers, Scott A, Armstrong, Patrick, Brown, Daniel, De Carvalho, Nada, Jabado, Lynley, Marshall, Miguel, Rivera, Malcolm, Smith, Peter C, Adamson, Amy, Barone, Christian, Baumann, Samuel, Blackman, Vickie, Buenger, Martha, Donoghue, Aundrietta D, Duncan, Elizabeth, Fox, Brian, Gadbaw, Maureen, Hattersley, Peter, Ho, Ira, Jacobs, Michael J, Kelly, Mark, Kieran, Giovanni, Lesa, Franca, Ligas, Donna, Ludwinski, Joe, McDonough, Zariana, Nikolova, Koen, Norga, Adrian, Senderowicz, Tilmann, Taube, Susan, Weiner, Dominik, Karres, Gilles, Vassal
Publikováno v:
European journal of cancer
The fifth multistakeholder Paediatric Strategy Forum focussed on epigenetic modifier therapies for children and adolescents with cancer. As most mutations in paediatric malignancies influence chromatin-associated proteins or transcription and paediat
Publikováno v:
Journal of Visualized Experiments.
Mass cytometry utilizes antibodies conjugated with heavy metal labels, an approach that has greatly increased the number of parameters and opportunities for deep analysis well beyond what is possible with conventional fluorescence-based flow cytometr
Publikováno v:
Molecular and Cellular Biology. 34:2695-2709
Tumor suppressor p53 protects cells from genomic insults and is a target of mutation in more than 50% of human cancers. Stress-mediated modification and increased stability of p53 promote p53 interaction with chromatin, which results in transcription
Autor:
Jeffrey T. Chang, Aundrietta D. Duncan, Michael Z. Gilcrease, Vrutant Shah, Clinton Yam, Stacy L. Moulder, Michelle Craig Barton
Publikováno v:
Cancer Research. 78:4626-4626
Background: TRIM24 is a multifunctional, epigenetic PHD/Bromodomain protein that negatively regulates p53, via an E3-ubiquitin ligase RING domain, and co-regulates transcription. Over-expression of TRIM24 in murine mammary epithelium results in the d