Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aula Ammar"'
Autor:
Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. I
Externí odkaz:
https://doaj.org/article/3b63169b435447a19a5fb490ee037279
Publikováno v:
Molecules, Vol 26, Iss 4, p 775 (2021)
Cancer is one of the leading causes of death worldwide, with a mortality rate of more than 9 million deaths reported in 2018. Conventional anti-cancer therapy can greatly improve survival however treatment resistance is still a major problem especial
Externí odkaz:
https://doaj.org/article/1b653545e3254405a1fc96c22b4b8ff4
Autor:
Aula Ammar, Rabab A. A. Mohammed, Marko Salmi, Michael Pepper, Emma C. Paish, Ian O. Ellis, Stewart G. Martin
Publikováno v:
Analytical Cellular Pathology, Vol 34, Iss 1-2, Pp 67-78 (2011)
Background: Mechanisms regulating breast cancer lymph node metastasis are unclear. Staining of CLEVER-1 (common lymphatic endothelial and vascular endothelial receptor-1) in human breast tumors was used, along with in vitro techniques, to assess invo
Externí odkaz:
https://doaj.org/article/04262e6fb4d54f0fbb195fc83cb845ee
Publikováno v:
AIP Conference Proceedings; 2024, Vol. 3105 Issue 1, p1-7, 7p
Autor:
Lily V. Hillson, Ross K. McMahon, Kathryn A. Pennel, Jean A. Quinn, Leia Jones, Raheleh Amirkhah, Aula Ammar, Phimmada Hatthakarnkul, Annabelle Ferguson, Simon W. Milling, Alec McDonald, Philip D. Dunne, Joanne Edwards, Sean M. O'Cathail, Campbell S. Roxburgh
Publikováno v:
Cancer Research. 83:3231-3231
Background. Two pre-operative radiotherapy (RT) regimens are in common use for patients (pts) with locally advanced rectal cancer (LARC): Conventionally fractionated, long course chemoradiation (LCCRT, 25x1.8Gy with concomitant chemotherapy) or hypof
Autor:
Hester C. van Wyk, Phimmada Hatthakarnkul, Amna Ahmed Mohemmd Matly, Aula Ammar, Donald C. McMillan, Joanne Edwards, Jean A. Quinn
Publikováno v:
Critical reviews in oncology/hematology. 167
Introduction:\ud Despite a well-known prognostic role in colorectal cancer, the genomic profiling of tumour budding remains to be elucidated. We aim to review the association of common mutations with tumour budding.\ud \ud Methods:\ud A systematic re
Autor:
Andrew R. Green, Sarah J. Storr, Aula Ammar, Emad A. Rakha, Stewart G. Martin, Narmeen S Ahmad, Ian O. Ellis
Publikováno v:
Cancer Immunology, Immunotherapy
Macrophage-associated cytokines play an important role in cancer metastasis; however, the functions of interleukins (IL) 6 and 10 in breast cancer (BC) progression and metastasis are not clear. In this study the roles of IL-6/IL-10 in regulating vasc
Autor:
Christoph Schliemann, Uzma Qureshi, Aula Ammar, Dario Neri, RB Pedley, Jessica Mårlind, J. Ahlskog
Publikováno v:
British Journal of Cancer; Vol 101
British Journal of Cancer, 101 (4)
British Journal of Cancer
British Journal of Cancer, 101 (4)
British Journal of Cancer
Background: Hypoxia, which is commonly observed in areas of primary tumours and of metastases, influences response to treatment. However, its characterisation has so far mainly been restricted to the ex vivo analysis of tumour sections using monoclon
Autor:
Li-Chen Han, Aula Ammar, Stewart G. Martin, Sarah J. Storr, John E. Moses, Nurul Akmaryanti Abdullah
Publikováno v:
Cancer Research. 77:5210-5210
Background: Breast cancer is the most common cancer in women in the United Kingdom. The glutathione (GSH) system is a major redox buffering system involved in regulating radioresponse of cancer cells. Overexpression has been shown to cause multidrug
Publikováno v:
Clinical Cancer Investigation Journal. 3:388
Background: Cancer progression is a complex process consisting of a series of distinct steps. Cysteine proteases, such as cathepsins (Cts), are important molecules that play a central role in cancer progression and metastasis. Previous studies on hum