Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Augustus M. C. Tilley"'
Autor:
Sangita Sridharan, Megan Robeson, Diwakar Bastihalli-Tukaramrao, Cory M. Howard, Boopathi Subramaniyan, Augustus M. C. Tilley, Amit K. Tiwari, Dayanidhi Raman
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Breast cancer stem cells (BCSCs) are intrinsically chemoresistant and capable of self-renewal. Following chemotherapy, patients can develop minimal residual disease due to BCSCs which can repopulate into a relapsed tumor. Therefore, it is imperative
Externí odkaz:
https://doaj.org/article/e8ee31b99cd7475bb49c34f049838ae0
Autor:
Sangita Sridharan, Cory M. Howard, Augustus M. C. Tilley, Boopathi Subramaniyan, Amit K. Tiwari, Randall J. Ruch, Dayanidhi Raman
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Breast cancer stem cells (BCSCs) play a vital role in tumor progression and metastasis. They are heterogeneous and inherently radio- and chemoresistant. They have the ability to self-renew and differentiate into non-BCSCs. These determinants of BCSCs
Externí odkaz:
https://doaj.org/article/c3974e1d915f4b4f8962e2e1077b5406
Publikováno v:
Advances in Cancer Signal Transduction and Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb56bcc6284b7a9e13bc9131d72d3de
https://doi.org/10.2174/9789811458118120010004
https://doi.org/10.2174/9789811458118120010004
Autor:
Cory M. Howard, Ivana L. de la Serna, Sangita Sridharan, Boopathi Subramaniyan, Tupa Basuroy, Dayanidhi Raman, Augustus M C Tilley, Elke Butt
Publikováno v:
Cancers, Vol 12, Iss 2372, p 2372 (2020)
Cancers
Volume 12
Issue 9
Cancers
Volume 12
Issue 9
The CXCL12-CXCR4 axis plays a vital role in many steps of breast cancer metastasis, but the molecular mechanisms have not been fully elucidated. We previously reported that activation of CXCR4 by CXCL12 promotes the nuclear localization of LASP1 (LIM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897b210cdcb302cd30b5d770e73d39f8
https://www.mdpi.com/2072-6694/12/9/2372
https://www.mdpi.com/2072-6694/12/9/2372
Autor:
Sangita Sridharan, Cory M. Howard, Nicole R. Bearss, Boopathi Subramaniyan, Augustus M C Tilley, Sawsan Alkhalili, Dayanidhi Raman
Publikováno v:
Cancers, Vol 12, Iss 2455, p 2455 (2020)
Cancers
Volume 12
Issue 9
Cancers
Volume 12
Issue 9
Simple Summary CXCR4 is critically involved in triple-negative breast cancer metastasis. LASP1 was previously found to be necessary for CXCR4-dependent tumor cell invasion. Here we aimed to understand how LASP1 can have such a powerful role this proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec94dd8a3ff7f16ba619cb51df995665
https://www.mdpi.com/2072-6694/12/9/2455
https://www.mdpi.com/2072-6694/12/9/2455
Autor:
Augustus M C Tilley, Boopathi Subramaniyan, Sangita Sridharan, Cory M. Howard, Amit K. Tiwari, Dayanidhi Raman, Randall J. Ruch
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology
Frontiers in Oncology
Breast cancer stem cells (BCSCs) play a vital role in tumor progression and metastasis. They are heterogeneous and inherently radio- and chemoresistant. They have the ability to self-renew and differentiate into non-BCSCs. These determinants of BCSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3660fd76e39b7bb7fd681859551924e0
https://doi.org/10.3389/fonc.2019.01003
https://doi.org/10.3389/fonc.2019.01003
Autor:
Cory M. Howard, Boopathi Subramaniyan, Amit K. Tiwari, Dayanidhi Raman, Diwakar Bastihalli-Tukaramrao, Megan Robeson, Sangita Sridharan, Augustus M C Tilley
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology, Vol 9 (2019)
Breast cancer stem cells (BCSCs) are intrinsically chemoresistant and capable of self-renewal. Following chemotherapy, patients can develop minimal residual disease due to BCSCs which can repopulate into a relapsed tumor. Therefore, it is imperative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a641776611454f46a7f7c5a8fa150d2f
https://pubmed.ncbi.nlm.nih.gov/31867270
https://pubmed.ncbi.nlm.nih.gov/31867270
Autor:
Augustus M C Tilley, Cory M. Howard, Christopher S. Fraser, Nicole R. Bearss, Boopathi Subramaniyan, Dayanidhi Raman, Nancy Villa, Sangita Sridharan
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Frontiers in oncology, vol 9, iss MAR
Frontiers in Oncology
Frontiers in oncology, vol 9, iss MAR
Frontiers in Oncology
Triple-negative breast cancer (TNBC) remains clinically challenging as effective targeted therapies are lacking. In addition, patient mortality mainly results from the metastasized lesions. CXCR4 has been identified to be one of the major chemokine r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c76130821283d43bd05213b057b4a9f
https://www.frontiersin.org/article/10.3389/fonc.2019.00284/full
https://www.frontiersin.org/article/10.3389/fonc.2019.00284/full
Autor:
Augustus M C Tilley, Dayanidhi Raman, Sangita Sridharan, Boopathi Subramaniyan, Cory M. Howard, Diwakar Tukaramrao Bastihalli, Megan Robeson
Publikováno v:
Cancer Research. 80:4959-4959
Chemoresistance is a clinically significant issue in triple-negative breast cancer (TNBC) patients, leading to minimal residual disease. The surviving breast cancer stem cells (BCSCs) undergo multilineage differentiation and repopulate a more aggress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59641b96aaec8ae873b901a654a796fc
https://doi.org/10.1158/1538-7445.am2020-4959
https://doi.org/10.1158/1538-7445.am2020-4959