Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Augusto F. Uberti"'
Autor:
Augusto F. Uberti, Natalia Callai-Silva, Matheus V. C. Grahl, Angela R. Piovesan, Eduarda G. Nachtigall, Cristiane R. G. Furini, Celia Regina Carlini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3091 (2022)
Alzheimer’s disease (AD) causes dementia and memory loss in the elderly. Deposits of beta-amyloid peptide and hyperphosphorylated tau protein are present in a brain with AD. A filtrate of Helicobacter pylori’s culture was previously found to indu
Externí odkaz:
https://doaj.org/article/43560e55985e4f36af9a65e75ad15ba2
Autor:
Matheus V. C. Grahl, Augusto F. Uberti, Valquiria Broll, Paula Bacaicoa-Caruso, Evelin F. Meirelles, Celia R. Carlini
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7205 (2021)
Infection by Proteus mirabilis causes urinary stones and catheter incrustation due to ammonia formed by urease (PMU), one of its virulence factors. Non-enzymatic properties, such as pro-inflammatory and neurotoxic activities, were previously reported
Externí odkaz:
https://doaj.org/article/7759a846c7a74641806108793005f065
The Impact of Helicobacter pylori Urease upon Platelets and Consequent Contributions to Inflammation
Autor:
Adriele Scopel-Guerra, Deiber Olivera-Severo, Fernanda Staniscuaski, Augusto F. Uberti, Natália Callai-Silva, Natália Jaeger, Bárbara N. Porto, Celia R. Carlini
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Gastric infection by Helicobacter pylori is considered a risk factor for gastric and duodenal cancer, and extragastric diseases. Previous data have shown that, in a non-enzymatic way, H. pylori urease (HPU) activates neutrophils to produce ROS and al
Externí odkaz:
https://doaj.org/article/824db815e4f94ff88194cf216b578fcd
Autor:
Deiber Olivera-Severo, Augusto F. Uberti, Miguel S. Marques, Marta T. Pinto, Maria Gomez-Lazaro, Céu Figueiredo, Marina Leite, Célia R. Carlini
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Helicobacter pylori is a pathogen involved in gastric diseases such as ulcers and carcinomas. H. pylori’s urease is an important virulence factor produced in large amounts by this bacterium. In previous studies, we have shown that this protein is a
Externí odkaz:
https://doaj.org/article/aaffcb2f1c444e67beddc3b9f59c2986
Autor:
Augusto F. Uberti, Leonardo L. Fruttero, Valquiria Broll, Fernanda Cortez Lopes, Matheus V. Coste Grahl, Célia R. Carlini, Rodrigo Ligabue-Braun, Natalia R. Moyetta, Anne H.S. Martinelli, Diogo Ribeiro Demartini, Ana Paula A. Perin
Publikováno v:
Process Biochemistry. 110:263-274
Ureases are moonlighting proteins displaying non-catalytic properties, including platelet activation, antifungal and entomotoxic effects. The structure-activity mapping of these properties is poorly developed. Proteus mirabilis urease (PMU) consists
Autor:
Augusto F. Uberti, Matheus V. Coste Grahl, Paula Bacaicoa-Caruso, Evelin F Meirelles, Célia R. Carlini, Valquiria Broll
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7205, p 7205 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 7205, p 7205 (2021)
Infection by Proteus mirabilis causes urinary stones and catheter incrustation due to ammonia formed by urease (PMU), one of its virulence factors. Non-enzymatic properties, such as pro-inflammatory and neurotoxic activities, were previously reported
Autor:
Valquiria Broll, Ana Paula A. Perin, Augusto F. Uberti, Leonardo L. Fruttero, Célia R. Carlini, Matheus V. Coste Grahl, Fernanda Stanisçuaski, Natalia R. Moyetta
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 200:17-26
Jaburetox is a recombinant peptide derived from a Canavalia ensiformis urease that presents toxic effects uponseveral species of insects, phytopathogenic fungi and yeasts of medical importance. So far, no toxicity of Jaburetoxto mammals has been show
Autor:
Augusto F. Uberti, Lilian Etelvina Canavoso, Ana Paula A. Perin, Fernanda Cortez Lopes, Leonardo L. Fruttero, Fernanda Stanisçuaski, Matheus V. Coste Grahl, Bárbara N. Porto
Publikováno v:
Pesticide Biochemistry and Physiology. 167:104591
Extracellular traps (ETs) are extracellular nucleic acids associated with cytoplasmic proteins that may aid in the capture and killing of pathogens. To date, only a few insects were shown to display this kind of immune response. Jaburetox, a peptide
Autor:
Adriele Scopel-Guerra, Christina Barja-Fidalgo, Célia R. Carlini, Edward Helal-Neto, Deiber Olivera-Severo, João Alfredo Moraes, Mariele de Jesus Souza, Vany Nascimento Da Silva, Augusto F. Uberti
Publikováno v:
Helicobacter. 24:e12573
Background Helicobacter pylori urease (HPU) is a key virulence factor that enables bacteria to colonize and survive in the stomach. We early demonstrated that HPU, independent of its catalytic activity, induced inflammatory and angiogenic responses i
Autor:
Adriele Scopel-Guerra, Célia R. Carlini, Augusto F. Uberti, Christina Barja-Fidalgo, Deiber Olivera-Severo, German Enrique Wassermann, João Alfredo Moraes, Pedro Barcellos-de-Souza
Publikováno v:
Toxicon. 69:240-249
The gastric pathogen Helicobacter pylori produces large amounts of urease, whose enzyme activity enables the bacterium to survive in the stomach. We have previously shown that ureases display enzyme-independent effects in mammalian models, most throu