MHConstructor: a high-throughput, haplotype-informed solution to the MHC assembly challenge.

Autor: Wade KJ; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Suseno R; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Kizer K; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Williams J; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Boquett J; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Caillier S; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Pollock NR; Department of Biomedical Informatics, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA.; Department of Immunology and Microbiology, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA., Renschen A; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Santaniello A; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Oksenberg JR; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Norman PJ; Department of Biomedical Informatics, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA.; Department of Immunology and Microbiology, Anschutz Medical Campus, University of Colorado, Aurora, CO, USA., Augusto DG; Department of Biological Sciences, University of North Carolina Charlotte, Charlotte, NC, USA.; Programa de Pós-Graduação em Genética, Universidade Federal do Paraná, Curitiba, Brazil., Hollenbach JA; Department of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA. jill.hollenbach@ucsf.edu.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA. jill.hollenbach@ucsf.edu.

Publikováno v: Genome biology [Genome Biol] 2024 Oct 17; Vol. 25 (1), pp. 274. Date of Electronic Publication: 2024 Oct 17.

The 18th International HLA & Immunogenetics workshop project report: Creating fully representative MHC reference haplotypes.

Autor: Pollock NR; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA.; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Farias TDJ; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA.; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Kichula KM; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA.; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Sauter J; DKMS Group, Tübingen, Germany.; DKMS Life Science Lab, Dresden, Germany., Scholz S; Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Nii-Trebi NI; Department of Medical Laboratory Sciences, School of Biomedical & Allied Health Sciences, College of Health Sciences, University of Ghana, Accra, Ghana., Khor SS; Genome Medical Science Project, National Center for Global Health and Medicine Hospital, Tokyo, Japan.; Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore., Tokunaga K; Genome Medical Science Project, National Center for Global Health and Medicine Hospital, Tokyo, Japan., Voorter CE; Department of Transplantation Immunology, Tissue Typing Laboratory, Maastricht University Medical Center, Maastricht, Netherlands., Groeneweg M; Department of Transplantation Immunology, Tissue Typing Laboratory, Maastricht University Medical Center, Maastricht, Netherlands., Augusto DG; Department of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, North Carolina, USA., Arrieta-Bolaños E; Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), partner site Essen/Düsseldorf, Heidelberg, Germany., Mayor NP; Anthony Nolan Research Institute, Royal Free Hospital, London, UK.; UCL Cancer Institute, Royal Free Campus, London, UK., Edinur HA; School of Health Sciences, Universiti Sains Malaysia, Kelantan, Malaysia., ElGhazali G; Immunology laboratory, Sheikh Khalifa Medical City- Purelab, Purehealth, Abu Dhabi and College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates., Issler HC; Laboratory of Human Molecular Genetics, Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba, Brazil., Petzl-Erler ML; Laboratory of Human Molecular Genetics, Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba, Brazil., Oksenberg JR; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, California, USA., Marin WM; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, California, USA., Hollenbach JA; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, California, USA.; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA., Gendzekhadze K; HLA Laboratory, Department of Hematology and HCT, City of Hope National Medical Center, Duarte, California, USA., Cita R; Transplant Immunology Laboratory, Pio XII Foundation, Barretos, Brazil., Stelet V; Immunogenetics Laboratory, National Cancer Institute, Rio de Janeiro, Brazil., Rajalingam R; Immunogenetics and Transplantation Laboratory, Department of Surgery, University of California San Francisco, San Francisco, California, USA., Koskela S; Research and Development, Finnish Red Cross Blood Service, Vantaa, Finland., Clancy J; Research and Development, Finnish Red Cross Blood Service, Vantaa, Finland., Chatzistamatiou T; Histocompatibility & Immunogenetics Laboratory, Hellenic Cord Blood Bank, Biomedical Research Foundation, Academy of Athens, Athens, Greece., Houwaart T; Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Kulski J; Department of Molecular Life Science, Tokai University School of Medicine, Isehara, Japan., Guethlein LA; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA., Parham P; Department of Structural Biology and Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA., Schmidt AH; DKMS Group, Tübingen, Germany.; DKMS Life Science Lab, Dresden, Germany., Dilthey A; Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Norman PJ; Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA.; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Publikováno v: HLA [HLA] 2024 Jun; Vol. 103 (6), pp. e15568.

An autoantibody signature predictive for multiple sclerosis.

Autor: Zamecnik CR; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Sowa GM; University of California, San Francisco School of Medicine, San Francisco, CA, USA.; Department of Medicine, McGaw Medical Center of Northwestern University, Chicago, IL, USA., Abdelhak A; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Dandekar R; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Bair RD; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Wade KJ; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Bartley CM; Department of Psychiatry and Behavioral Sciences, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Kizer K; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Augusto DG; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA., Tubati A; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Gomez R; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Fouassier C; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Gerungan C; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Caspar CM; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Alexander J; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Wapniarski AE; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Loudermilk RP; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Eggers EL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Zorn KC; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA., Ananth K; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Jabassini N; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Mann SA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub San Francisco, San Francisco, CA, USA., Ragan NR; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Santaniello A; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Henry RG; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Baranzini SE; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Zamvil SS; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Sabatino JJ Jr; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Bove RM; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Guo CY; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Gelfand JM; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Cuneo R; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., von Büdingen HC; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Oksenberg JR; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Cree BAC; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Hollenbach JA; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA., Green AJ; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Hauser SL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Wallin MT; Department of Veterans Affairs, Multiple Sclerosis Center of Excellence, Washington, DC, USA.; University of Maryland School of Medicine, Baltimore, MD, USA., DeRisi JL; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA.; Chan Zuckerberg Biohub San Francisco, San Francisco, CA, USA., Wilson MR; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA. michael.wilson@ucsf.edu.

Publikováno v: Nature medicine [Nat Med] 2024 May; Vol. 30 (5), pp. 1300-1308. Date of Electronic Publication: 2024 Apr 19.

Genetic Association and Differential RNA Expression of Histone (De)Acetylation-Related Genes in Pemphigus Foliaceus-A Possible Epigenetic Effect in the Autoimmune Response.

Autor: Sulzbach Denardin M; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil., Bumiller-Bini Hoch V; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil., Salviano-Silva A; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Lobo-Alves SC; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Research Institut Pelé Pequeno Príncipe, Curitiba 80250-060, Brazil., Adelman Cipolla G; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil., Malheiros D; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil., Augusto DG; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Department of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, NC 28223, USA., Wittig M; Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University of Kiel, 24105 Kiel, Germany., Franke A; Institute of Clinical Molecular Biology (IKMB), Christian-Albrechts-University of Kiel, 24105 Kiel, Germany., Pföhler C; Department of Dermatology, Saarland University Medical Center, 66421 Homburg, Germany., Worm M; Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany., van Beek N; Department of Dermatology, University of Lübeck, 23562 Lübeck, Germany., Goebeler M; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany., Sárdy M; Department of Dermatology and Allergy, University Hospital, LMU Munich, 80539 Munich, Germany.; Department of Dermatology, Venereology and Dermatooncology, Semmelweis University, 1085 Budapest, Hungary., Ibrahim S; College of Medicine and Health Sciences, Khalifa University, Abu Dhabi 127788, United Arab Emirates.; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, 23562 Lübeck, Germany., Busch H; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, 23562 Lübeck, Germany., Schmidt E; Department of Dermatology, University of Lübeck, 23562 Lübeck, Germany.; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, 23562 Lübeck, Germany., Hundt JE; Lübeck Institute of Experimental Dermatology (LIED), University of Lübeck, 23562 Lübeck, Germany., Petzl-Erler ML; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil., Beate Winter Boldt A; Laboratory of Human Molecular Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.; Postgraduate Program in Genetics, Department of Genetics, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.

Publikováno v: Life (Basel, Switzerland) [Life (Basel)] 2023 Dec 29; Vol. 14 (1). Date of Electronic Publication: 2023 Dec 29.

A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection.

Autor: Augusto DG; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA.; Department of Biological Sciences, The University of North Carolina at Charlotte, Charlotte, NC, USA.; Programa de Pós-Graduação em Genética, Universidade Federal do Paraná, Curitiba, Brazil., Murdolo LD; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., Chatzileontiadou DSM; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Sabatino JJ Jr; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Yusufali T; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Peyser ND; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Butcher X; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Kizer K; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Guthrie K; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA., Murray VW; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Pae V; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Sarvadhavabhatla S; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Beltran F; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Gill GS; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Lynch KL; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Yun C; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Maguire CT; Clinical and Translational Science Institute, University of Utah, Salt Lake City, UT, USA., Peluso MJ; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Hoh R; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Henrich TJ; Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Deeks SG; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Davidson M; Department of Medicine, University of California, San Francisco, CA, USA., Lu S; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Goldberg SA; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Kelly JD; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.; F.I. Proctor Foundation, University of California, San Francisco, CA, USA., Martin JN; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA., Vierra-Green CA; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN, USA., Spellman SR; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN, USA., Langton DJ; ExplantLab, Newcastle-upon-Tyne, UK., Dewar-Oldis MJ; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., Smith C; QIMR Berghofer Centre for Immunotherapy and Vaccine Development Brisbane, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Barnard PJ; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., Lee S; Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Marcus GM; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Olgin JE; Division of Cardiology, Department of Medicine, University of California, San Francisco, CA, USA., Pletcher MJ; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.; Division of General Internal Medicine, University of California, San Francisco, CA, USA., Maiers M; CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN, USA., Gras S; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Hollenbach JA; Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA, USA. jill.hollenbach@ucsf.edu.; Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. jill.hollenbach@ucsf.edu.

Publikováno v: Nature [Nature] 2023 Aug; Vol. 620 (7972), pp. 128-136. Date of Electronic Publication: 2023 Jul 19.