Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Augusto Bleve"'
Autor:
Gloriana Ndembe, Ilenia Intini, Massimo Moro, Chiara Grasselli, Andrea Panfili, Nicolò Panini, Augusto Bleve, Mario Occhipinti, Cristina Borzi, Marina Chiara Garassino, Mirko Marabese, Simone Canesi, Eugenio Scanziani, Gabriella Sozzi, Massimo Broggini, Monica Ganzinelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background About 10% of NSCLCs are mutated in KRAS and impaired in STK11/LKB1, a genetic background associated with poor prognosis, caused by an increase in metastatic burden and resistance to standard therapy. LKB1 is a protein involved in
Externí odkaz:
https://doaj.org/article/9430de048d034f9d86dd3b0f84f29a05
Autor:
Francesca Maria Consonni, Barbara Durante, Marcello Manfredi, Augusto Bleve, Chiara Pandolfo, Valentina Garlatti, Virginia Vita Vanella, Emilio Marengo, Elettra Barberis, Barbara Bottazzi, Sara Bombace, Ilaria My, Gianluigi Condorelli, Valter Torri, Antonio Sica
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Even though cancer patients are generally considered more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the mechanisms driving their predisposition to severe forms of coronavirus disease 2019 (COVID-19) have n
Externí odkaz:
https://doaj.org/article/cd79b754e270428c80b3122a228e5e7b
Autor:
Francesca Maria Consonni, Chiara Porta, Arianna Marino, Chiara Pandolfo, Silvia Mola, Augusto Bleve, Antonio Sica
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of immature myeloid cells with major regulatory functions and rise during pathological conditions, including cancer, infections and autoimmune conditions. MDSC expansion is
Externí odkaz:
https://doaj.org/article/0ee969d39d2447d190527f35dc5640aa
Autor:
Antonio Sica, Mario P. Colombo, Emilio Hirsch, Emilia Turco, Fiorella Balzac, Vincenzo Bronte, Gioacchino Natoli, Renato Ostuni, Viviana Piccolo, Stefano Duga, Giulia Soldà, Andrea Doni, Alessandro Ippolito, Silvia Tartari, Lorenza Rimassa, Tiziana Pressiani, Mariangela Storto, Stefania Banfi, Laura Strauss, Claudio Tripodo, Monica Rimoldi, Paola Larghi, Maria Grazia Totaro, Augusto Bleve, Sabina Sangaletti, Sara Morlacchi, Francesca Maria Consonni, Chiara Porta
selective gene expression alterations in p50-/- PEC stimulated with IFNγ for 4 hours as compared to WT PEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206cc04df1b560c7a93960190448cce1
https://doi.org/10.1158/0008-5472.22423011
https://doi.org/10.1158/0008-5472.22423011
Autor:
Antonio Sica, Mario P. Colombo, Emilio Hirsch, Emilia Turco, Fiorella Balzac, Vincenzo Bronte, Gioacchino Natoli, Renato Ostuni, Viviana Piccolo, Stefano Duga, Giulia Soldà, Andrea Doni, Alessandro Ippolito, Silvia Tartari, Lorenza Rimassa, Tiziana Pressiani, Mariangela Storto, Stefania Banfi, Laura Strauss, Claudio Tripodo, Monica Rimoldi, Paola Larghi, Maria Grazia Totaro, Augusto Bleve, Sabina Sangaletti, Sara Morlacchi, Francesca Maria Consonni, Chiara Porta
Myeloid-derived suppressor cells (MDSC) include immature monocytic (M-MDSC) and granulocytic (PMN-MDSC) cells that share the ability to suppress adaptive immunity and to hinder the effectiveness of anticancer treatments. Of note, in response to IFNγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd8bbef77a19705c085cfcf61781bbc
https://doi.org/10.1158/0008-5472.c.6511398.v1
https://doi.org/10.1158/0008-5472.c.6511398.v1
Autor:
Antonio Sica, Mario P. Colombo, Emilio Hirsch, Emilia Turco, Fiorella Balzac, Vincenzo Bronte, Gioacchino Natoli, Renato Ostuni, Viviana Piccolo, Stefano Duga, Giulia Soldà, Andrea Doni, Alessandro Ippolito, Silvia Tartari, Lorenza Rimassa, Tiziana Pressiani, Mariangela Storto, Stefania Banfi, Laura Strauss, Claudio Tripodo, Monica Rimoldi, Paola Larghi, Maria Grazia Totaro, Augusto Bleve, Sabina Sangaletti, Sara Morlacchi, Francesca Maria Consonni, Chiara Porta
supplementary figures and Materials & Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455400f203bdb1b12f749e98283ef8c9
https://doi.org/10.1158/0008-5472.22423017
https://doi.org/10.1158/0008-5472.22423017
Publikováno v:
Clinical Reviews in Allergy & Immunology
The immune system is the central regulator of tissue homeostasis, ensuring tissue regeneration and protection against both pathogens and the neoformation of cancer cells. Its proper functioning requires homeostatic properties, which are maintained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16af0a28eb38a643099988d4e325189b
https://doi.org/10.1007/s12016-021-08909-7
https://doi.org/10.1007/s12016-021-08909-7
Autor:
Viviana Piccolo, Augusto Bleve, Renato Ostuni, Sara Morlacchi, Monica Rimoldi, Chiara Porta, Silvia Tartari, Mario P. Colombo, Alessandro Ippolito, Mariangela Storto, Giulia Soldà, Paola Larghi, Sabina Sangaletti, Stefano Duga, Claudio Tripodo, Tiziana Pressiani, Gioacchino Natoli, Lorenza Rimassa, Laura Strauss, Antonio Sica, Emilio Hirsch, Andrea Doni, Vincenzo Bronte, Stefania Banfi, Fiorella Balzac, Francesca Maria Consonni, Maria Grazia Totaro, Emilia Turco
Publikováno v:
Cancer Research. 80:2874-2888
Myeloid-derived suppressor cells (MDSC) include immature monocytic (M-MDSC) and granulocytic (PMN-MDSC) cells that share the ability to suppress adaptive immunity and to hinder the effectiveness of anticancer treatments. Of note, in response to IFNγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3968aacb6c38899fd2b3728db43197
https://doi.org/10.1158/0008-5472.can-19-2843
https://doi.org/10.1158/0008-5472.can-19-2843
Publikováno v:
Cancers, Vol 14, Iss 510, p 510 (2022)
In recent years, the immune system has emerged as a critical regulator of tumor development, progression and dissemination. Advanced therapeutic approaches targeting immune cells are currently under clinical use and improvement for the treatment of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02c9f0f7b33e10b2880bd54975711f0
https://www.mdpi.com/2072-6694/14/3/510
https://www.mdpi.com/2072-6694/14/3/510
Autor:
Paolo Kunderfranco, Andrea Doni, Giulia Grazia, Roberta Mortarini, Massimo Milione, Francesco Sgambelluri, Chiara Alì, Andrea Anichini, Alberto Termanini, Andrea Maurichi, Marco Fabbri, Mariangela Storto, Eliana Rulli, Laura Gribaldo, Chiara Pandolfo, Marco Erreni, Francesca Maria Consonni, Antonio Sica, Augusto Bleve, Mario Santinami, Maria Grazia Totaro, Valter Torri, Fabio Pasqualini, Miguel P. Soares
Publikováno v:
Nature immunology. 22(5)
Although the pathological significance of tumor-associated macrophage (TAM) heterogeneity is still poorly understood, TAM reprogramming is viewed as a promising anticancer therapy. Here we show that a distinct subset of TAMs (F4/80hiCD115hiC3aRhiCD88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d287b88a7e651c4fabe0084aaedac
https://pubmed.ncbi.nlm.nih.gov/33903766
https://pubmed.ncbi.nlm.nih.gov/33903766