Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Augusto Amici"'
Autor:
Lishan Cui, Junbiao Wang, Fiorenza Orlando, Robertina Giacconi, Marco Malavolta, Beatrice Bartozzi, Roberta Galeazzi, Giorgia Giorgini, Luca Pesce, Francesco Cardarelli, Erica Quagliarini, Serena Renzi, Siyao Xiao, Daniela Pozzi, Mauro Provinciali, Giulio Caracciolo, Cristina Marchini, Augusto Amici
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34624-34635 (2024)
Externí odkaz:
https://doaj.org/article/0060469d652c4b548de5d8976672ba5b
Autor:
Cristina Andreani, Caterina Bartolacci, Giuseppe Persico, Francesca Casciaro, Stefano Amatori, Mirco Fanelli, Marco Giorgio, Mirco Galié, Daniele Tomassoni, Junbiao Wang, Xiaoting Zhang, Gregory Bick, Roberto Coppari, Cristina Marchini, Augusto Amici
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract The histone deacetylase sirtuin 6 (SIRT6) has been endowed with anti-cancer capabilities in many tumor types. Here, we investigate the impact of SIRT6-overexpression (SIRT6-OE) in Delta16HER2 mice, which are a bona fide model of HER2-positiv
Externí odkaz:
https://doaj.org/article/8139fbb56d614a27a117f5c1c6e0780d
Autor:
Junbiao Wang, Daniela Beghelli, Augusto Amici, Stefania Sut, Stefano Dall’Acqua, Giulio Lupidi, Diego Dal Ben, Onelia Bistoni, Daniele Tomassoni, Barbara Belletti, Sanaa Musa, Jamal Mahajna, Stefania Pucciarelli, Cristina Marchini
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1454 (2024)
Inonotus obliquus (Chaga) is a medicinal mushroom with several pharmacological properties that is used as a tea in traditional Chinese medicine. In this study, Chaga water extract was digested in vitro to mimic the natural processing and absorption o
Externí odkaz:
https://doaj.org/article/d35172e8b0504be081dd1073cbf20068
Autor:
Lishan Cui, Serena Renzi, Erica Quagliarini, Luca Digiacomo, Heinz Amenitsch, Laura Masuelli, Roberto Bei, Gianmarco Ferri, Francesco Cardarelli, Junbiao Wang, Augusto Amici, Daniela Pozzi, Cristina Marchini, Giulio Caracciolo
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1698 (2022)
DNA vaccination has been extensively studied as a promising strategy for tumor treatment. Despite the efforts, the therapeutic efficacy of DNA vaccines has been limited by their intrinsic poor cellular internalization. Electroporation, which is based
Externí odkaz:
https://doaj.org/article/8fc400ad756e4dac8c6808b1bf03df86
Autor:
Stefano Pierini, Abhishek Mishra, Renzo Perales-Linares, Mireia Uribe-Herranz, Silvia Beghi, Andrea Giglio, Sergei Pustylnikov, Francesca Costabile, Augusto Amici, John G Facciponte, Costantinos Koumenis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Tumor endothelial marker 1 (TEM1) is a protein expressed in the tumor-associated endothelium and/or stroma of various types of cancer. We previously demonstrated that immunization with a plasmid-DNA vaccine targeting TEM1 reduced tumor pro
Externí odkaz:
https://doaj.org/article/9300db75f4124b248835f3bd85865164
Autor:
Rossana Galassi, Lorenzo Luciani, Valentina Gambini, Silvia Vincenzetti, Giulio Lupidi, Augusto Amici, Cristina Marchini, Junbiao Wang, Stefania Pucciarelli
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
A class of phosphane gold(I) compounds, made of azoles and phosphane ligands, was evaluated for a screening on the regards of Breast Cancer cell panels (BC). The compounds possess N-Au-P or Cl-Au-P bonds around the central metal, and they differ for
Externí odkaz:
https://doaj.org/article/d62b3c92745a474392a1793e79a670e8
Autor:
Rossana Galassi, Lorenzo Luciani, Junbiao Wang, Silvia Vincenzetti, Lishan Cui, Augusto Amici, Stefania Pucciarelli, Cristina Marchini
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 80 (2022)
Breast cancers (BCs) may present dramatic diagnoses, both for ineffective therapies and for the limited outcomes in terms of lifespan. For these types of tumors, the search for new drugs is a primary necessity. It is widely recognized that gold compo
Externí odkaz:
https://doaj.org/article/7da8a46bb4064ab99d63ef0bbf219080
Autor:
Erica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui, Junbiao Wang, Augusto Amici, Cristina Marchini, Daniela Pozzi, Giulio Caracciolo
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1292 (2021)
In recent years, lipid nanoparticles (LNPs) have gained considerable attention in numerous research fields ranging from gene therapy to cancer immunotherapy and DNA vaccination. While some RNA-encapsulating LNP formulations passed clinical trials, DN
Externí odkaz:
https://doaj.org/article/a4bdbd952b574c60976f3fdea73c3bc7
Autor:
Silvia Grasso, Jennifer Chapelle, Vincenzo Salemme, Simona Aramu, Isabella Russo, Nicoletta Vitale, Ludovica Verdun di Cantogno, Katiuscia Dallaglio, Isabella Castellano, Augusto Amici, Giorgia Centonze, Nanaocha Sharma, Serena Lunardi, Sara Cabodi, Federica Cavallo, Alessia Lamolinara, Lorenzo Stramucci, Enrico Moiso, Paolo Provero, Adriana Albini, Anna Sapino, Johan Staaf, Pier Paolo Di Fiore, Giovanni Bertalot, Salvatore Pece, Daniela Tosoni, Stefano Confalonieri, Manuela Iezzi, Paola Di Stefano, Emilia Turco, Paola Defilippi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
p140Cap adaptor proteins interfere with adhesion and growth factor-dependent signalling in cancer cells but the mechanisms are unclear. Here the authors show that p140Cap interferes with ERBB2-dependent activation of Rac GTPase-controlled circuitries
Externí odkaz:
https://doaj.org/article/3f467620764d4f4e9419cd933a8e92a7
Autor:
Annalisa Candelori, Takaharu G. Yamamoto, Masaaki Iwamoto, Maura Montani, Augusto Amici, Adriana Vallesi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
In the ciliate Euplotes raikovi, a 631-amino acid Er-MAPK1 protein kinase was found to localize in nucleoli of the transcriptionally active nucleus (macronucleus) and act as a key component of an autocrine, cell-growth promoting self-signaling mechan
Externí odkaz:
https://doaj.org/article/e59aea917010495a9b0a954c924b4e4b