Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Augustine M. K. Choi"'
Autor:
Richa Batra, Rie Uni, Oleh M. Akchurin, Sergio Alvarez-Mulett, Luis G. Gómez-Escobar, Edwin Patino, Katherine L. Hoffman, Will Simmons, William Whalen, Kelsey Chetnik, Mustafa Buyukozkan, Elisa Benedetti, Karsten Suhre, Edward Schenck, Soo Jung Cho, Augustine M. K. Choi, Frank Schmidt, Mary E. Choi, Jan Krumsiek
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-10 (2023)
Abstract Background Acute respiratory distress syndrome (ARDS), a life-threatening condition during critical illness, is a common complication of COVID-19. It can originate from various disease etiologies, including severe infections, major injury, o
Externí odkaz:
https://doaj.org/article/73b7e4f3cafd424db0c9cb48062b9e13
Autor:
Frank Schmidt, Houari B. Abdesselem, Karsten Suhre, Nishant N. Vaikath, Muhammad U. Sohail, Maryam Al-Nesf, Ilham Bensmail, Fathima Mashod, Hina Sarwath, Joerg Bernhardt, Stephanie Schaefer-Ramadan, Ti-Myen Tan, Priscilla E. Morris, Edward J. Schenck, David Price, Vidya Mohamed-Ali, Mohammed Al-Maadheed, Abdelilah Arredouani, Julie Decock, Jonathan M. Blackburn, Augustine M. K. Choi, Omar M. El-Agnaf
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: Coronavirus disease (COVID-19) manifests many clinical symptoms, including an exacerbated immune response and cytokine storm. Autoantibodies in COVID-19 may have severe prodromal effects that are poorly understood. The interaction between
Externí odkaz:
https://doaj.org/article/cafc2cc0758a400281587d6a1c37112f
Autor:
Barbara D. Summers, Kihwan Kim, Cristina C. Clement, Zohaib Khan, Sangeetha Thangaswamy, Jacob McCright, Katharina Maisel, Sofia Zamora, Stephanie Quintero, Alexandra C. Racanelli, David Redmond, Jeanine D’Armiento, Jisheng Yang, Amy Kuang, Laurel Monticelli, Mark L. Kahn, Augustine M. K. Choi, Laura Santambrogio, Hasina Outtz Reed
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The lymphatic vasculature is critical for lung function, but defects in lymphatic function in the pathogenesis of lung disease is understudied. In mice, lymphatic dysfunction alone is sufficient to cause lung injury that resembles human emph
Externí odkaz:
https://doaj.org/article/65625e4b867f4e81924ccad4d01752a0
Autor:
Richa Batra, William Whalen, Sergio Alvarez-Mulett, Luis G. Gomez-Escobar, Katherine L. Hoffman, Will Simmons, John Harrington, Kelsey Chetnik, Mustafa Buyukozkan, Elisa Benedetti, Mary E. Choi, Karsten Suhre, Edward Schenck, Augustine M. K. Choi, Frank Schmidt, Soo Jung Cho, Jan Krumsiek
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9 (2022)
Background Acute respiratory distress syndrome (ARDS), a life-threatening condition characterized by hypoxemia and poor lung compliance, is associated with high mortality. ARDS induced by COVID-19 has similar clinical presentations and pathological m
Externí odkaz:
https://doaj.org/article/045db0b9a19544b4881ea62a59729541
Autor:
Luis G. Gómez-Escobar, Katherine L. Hoffman, Justin J. Choi, Alain Borczuk, Steven Salvatore, Sergio L. Alvarez-Mulett, Manuel D. Galvan, Zhen Zhao, Sabrina E. Racine-Brzostek, He S. Yang, Heather W. Stout-Delgado, Mary E. Choi, Augustine M. K. Choi, Soo Jung Cho, Edward J. Schenck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Increasing evidence has shown that Coronavirus disease 19 (COVID-19) severity is driven by a dysregulated immunologic response. We aimed to assess the differences in inflammatory cytokines in COVID-19 patients compared to contemporaneously h
Externí odkaz:
https://doaj.org/article/de6315cd729b4ccca1809ce8dcb1cf1d
Autor:
William Z. Zhang, Katherine L. Hoffman, Kristen T. Schiffer, Clara Oromendia, Michelle C. Rice, Igor Barjaktarevic, Stephen P. Peters, Nirupama Putcha, Russell P. Bowler, J. Michael Wells, David J. Couper, Wassim W. Labaki, Jeffrey L. Curtis, Meilan K. Han, Robert Paine, Prescott G. Woodruff, Gerard J. Criner, Nadia N. Hansel, Ivan Diaz, Karla V. Ballman, Kiichi Nakahira, Mary E. Choi, Fernando J. Martinez, Augustine M. K. Choi, Suzanne M. Cloonan
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background There is a lack of mechanism-driven, clinically relevant biomarkers in chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction, a proposed disease mechanism in COPD, is associated with the release of mitochondrial
Externí odkaz:
https://doaj.org/article/fda3f6f536e44b0baee73d681aa4e661
Autor:
Karsten Suhre, Hina Sarwath, Rudolf Engelke, Muhammad Umar Sohail, Soo Jung Cho, William Whalen, Sergio Alvarez-Mulett, Jan Krumsiek, Augustine M. K. Choi, Frank Schmidt
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Multiple studies have investigated the role of blood circulating proteins in COVID-19 disease using the Olink affinity proteomics platform. However, study inclusion criteria and sample collection conditions varied between studies, leading to sometime
Externí odkaz:
https://doaj.org/article/4225c005d4cc4dfe8655d4d9aa57ed52
Autor:
Kuei-Pin Chung, Chia-Lang Hsu, Li-Chao Fan, Ziling Huang, Divya Bhatia, Yi-Jung Chen, Shu Hisata, Soo Jung Cho, Kiichi Nakahira, Mitsuru Imamura, Mary E. Choi, Chong-Jen Yu, Suzanne M. Cloonan, Augustine M. K. Choi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Mitochondria of alveolar type 2 epithelial cells (AEC2) in the lung have been suggested to play a role in the development of idiopathic pulmonary fibrosis (IPF). Here the authors show that loss of mitofusin1 and mitofusin2 in murine AEC2 cells leads
Externí odkaz:
https://doaj.org/article/f5f243b5d4f24d84932e8612a7458e3a
Autor:
Pär I. Johansson, Kiichi Nakahira, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Laura E. Fredenburgh, John Harrington, Augustine M. K. Choi, Kenneth B. Christopher
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-9 (2018)
Abstract Background Cell-free plasma mitochondrial DNA (mtDNA) levels are associated with endothelial dysfunction and differential outcomes in critical illness. A substantial alteration in metabolic homeostasis is commonly observed in severe critical
Externí odkaz:
https://doaj.org/article/d8cb2159232f466d89b93403a74890e6
Autor:
Jinkyeong Park, Maria Pabon, Augustine M. K. Choi, Ilias I. Siempos, Laura E. Fredenburgh, Rebecca M. Baron, Kyeongman Jeon, Chi Ryang Chung, Jeong Hoon Yang, Chi-Min Park, Gee Young Suh
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Background Acute respiratory distress syndrome (ARDS) is potentially underrecognized by clinicians. Early recognition and subsequent optimal treatment of patients with ARDS may be facilitated by usage of biomarkers. Surfactant protein D (SP-
Externí odkaz:
https://doaj.org/article/6dec4df974954b1882cb0249243266d1