Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Augustine Eze"'
Autor:
Erin R. Bonner, Adam Dawood, Heather Gordish-Dressman, Augustine Eze, Surajit Bhattacharya, Sridevi Yadavilli, Sabine Mueller, Sebastian M. Waszak, Javad Nazarian
Publikováno v:
npj Genomic Medicine, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Recent genomic data points to a growing role for somatic mutations altering core histone and linker histone-encoding genes in cancer. However, the prevalence and the clinical and biological implications of histone gene mutations in malignant
Externí odkaz:
https://doaj.org/article/528cba2bc3bf46ee88c064c167920a47
Autor:
Erin R. Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N. Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P. Mickey Williams, Chris Karlovich, Amanda Peach, D’andra Howell, James Doroshow, Lindsay Kilburn, Roger J. Packer, Sabine Mueller, Javad Nazarian
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-6 (2022)
Abstract Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to the sensitive tumor location. We developed a targeted deep sequencing platform to detect tumor driver mutat
Externí odkaz:
https://doaj.org/article/9e314be8330c4153b226c12c059956f7
Autor:
Miriam Bornhorst, Augustine Eze, Surajit Bhattacharya, Ethan Putnam, M Isabel Almira‐Suarez, Christopher Rossi, Madhuri Kambhampati, Miguel Almalvez, Mariam Barseghyan, Nicole Del Risco, David Dotson, Joyce Turner, John S Myseros, Eric Vilain, Roger J Packer, Javad Nazarian, Brian Rood, Hayk Barseghyan
Publikováno v:
The Journal of Pathology.
Autor:
Miriam Bornhorst, Augustine Eze, Surajit Bhattacharya, Ethan Putnam, M. Isabel Almira-Suarez, Christopher Rossi, Madhuri Kambhampati, Miguel Almalvez, Mariam Barseghyan, Nicole Del Risco, David Dotson, Joyce Turner, John Myseros, Eric Vilain, Roger Packer, Javad Nazarian, Brian Rood, Hayk Barseghyan
Molecular characteristics of pediatric brain tumors have not only allowed for tumor subgrouping but have introduced novel treatment options for patients with specific tumor alterations. Therefore, an accurate histologic and molecular diagnosis is cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b44c15230d4dc395e73fe41a3689c9
https://doi.org/10.21203/rs.3.rs-1879445/v1
https://doi.org/10.21203/rs.3.rs-1879445/v1
EOLP-04. A CALL TO ACTION TO INCREASE ACCESS TO POST-MORTEM BRAIN TUMOR DONATIONS: GIFT FROM A CHILD
Autor:
Nicole Lyons, Angela Waanders, Melissa Williams, Javad Nazarian, Augustine Eze, Miriam Bornhorst, Elizabeth Frenkel, Jennifer Mason, Jane E Minturn, Mateusz Koptyra, Michelle Monje, Jared Hysinger, Mark Souweidane, Jeffery P Greenfield, Cindy Campbell, Esteban Uceda, Amy Smith, Julia Hegert, Stephani Campion, Ginny McLean, Patti Gustafson, Allen Gustafson
Publikováno v:
Neuro-Oncology. 24:vii108-vii109
Implementation of access to donate post mortem tissue among pediatric brain tumor patients remains a challenge[DSM1] . Previous attempts to develop a post-mortem network have been jeopardized by barriers such as a lack of education, logistical coordi
Autor:
Nirali Patel, Kathleen Felton, Surajit Bhattacharya, Maria Isabel Almira-Suarez, Augustine Eze, Joyce Turner, Robert Keating, Chima Oluigbo, Reuven J. Schore, Lindsay Kilburn, Roger J. Packer, John S. Myseros, Miriam Bornhorst
Publikováno v:
Journal of neurosurgery. Pediatrics.
OBJECTIVE Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome caused by germline mutations in the TP53 gene. CNS tumors are the fourth most common tumor type in LFS, and recent screening guidelines demonstrate that early tumor detection is
Autor:
Javad Nazarian, Krutika S. Gaonkar, Naomi E. Rance, Cassie Kline, Maria-Magdalena Georgescu, Roger J. Packer, Maria I Almira-Suarez, Adam C. Resnick, Erin R. Bonner, Madhuri Kambhampati, Mojca Stampar, Sabine Mueller, Angela Waanders, Karim Saoud, Sridevi Yadavilli, Eshini Panditharatna, Yong Kim, Augustine Eze, Lindsay Kilburn, Jamila Gittens, Sulgi Lee, Courtney L. Johnson, Miriam Bornhorst, Lauren Hancock, Eugene Hwang, Brian R. Rood, Cheng-Ying Ho
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Children diagnosed with brain tumors have the lowest overall survival of all pediatric cancers. Recent molecular studies have resulted in the discovery of recurrent driver mutations in many pediatric brain tumors. However, despite these molecular adv
Autor:
Adre J. du Plessis, Robin Baker, Nicole Herrera, Srinivas Kota, Rathinaswamy B. Govindan, Augustine Eze, Robert McCarter, Tareq Al-Shargabi, Laura Hitchings, Christopher B. Swisher, Sarah B. Mulkey, Stephanie Russo, G. Larry Maxwell
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
Delivery of the newborn occurs either vaginally or via caesarean section. It is not known whether the mode of delivery and exposure to labor affects early autonomic nervous system (ANS) function, as measured by heart rate variability (HRV), or cortic
Autor:
Erin R Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N Kline, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P Mickey Williams, Chris Karlovich, Amanda Peach, D'Andra Howell, James Doroshow, Lindsay Kilburn, Roger J Packer, Sabine Mueller, Javad Nazarian
Publikováno v:
Neuro-Oncology. 24:i29-i29
BACKGROUND: Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to sensitive neuroanatomical locations. Moreover, CNS tumors including diffuse midline glioma (DMG) exhibit
Autor:
Erin R Bonner, Xinyang Liu, Carlos Tor-Diez, Madhuri Kambhampati, Augustine Eze, Roger J Packer, Javad Nazarian, Marius George Linguraru, Miriam Bornhorst
Publikováno v:
Neuro-Oncology. 24:i29-i29
INTRODUCTION: Diffuse midline glioma (DMG) is a fatal childhood CNS tumor. Magnetic resonance imaging (MRI) is the gold standard for DMG diagnosis and monitoring of response to therapy. Leveraging novel MRI analytical approaches, including volumetric