Zobrazeno 1 - 10
of 26
pro vyhledávání: '"August P. Schubiger"'
Autor:
Linjing Mu, August P. Schubiger, Ananth Srinivasan, Timo Stellfeld, Keith Graham, Becaud Jessica, Ludger Dinkelborg, Ansgar Fitzner, Simon M. Ametamey, Ulrike Roehn
Publikováno v:
Journal of Fluorine Chemistry. 130:902-912
The direct labeling of biomolecules with fluorine-18 is highly desirable. An option is the ring-opening of an activated aziridine moiety in a biomolecule using 18 F-fluoride. Therefore, a series of aziridine-based model compounds and three aziridine-
Autor:
M. Honer, S.R. Malic, A. Johayem, August P. Schubiger, I. Novak, Simon M. Ametamey, Leonardo Scapozza
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 48:S312-S341
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 40:1794-1796
For decades nuclear medicine has been fostered as a selfsustaining medical monoculture. Since the 1950s, when focusing on the thyroid gland, nuclear medicine physicians were confident in embracing a holistic approach to the diagnosis and therapy of t
Autor:
August P. Schubiger, Roger Schibli
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 29:1529-1542
Contrary to common belief, organometallic compounds exhibit remarkable stability in aerobic and even diluted aqueous solutions. Technetium-sestamibi (Cardiolite) is one of the most prominent examples of this class of compounds routinely used in nucle
Autor:
Ilse Novak-Hofer, August P. Schubiger
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 29:821-830
The application of the beta particle-emitting nuclide 67Cu in radioimmunotherapy is reviewed. The production of the nuclide is outlined, and different production modes are discussed with an emphasis on cyclotron production. A short survey of copper c
Autor:
Nigel E.A. Crompton, Barbara Kaser-Hotz, U Roelcke, Peter Vontobel, Ilonka Guenther, Klaus L. Leenders, August P. Schubiger, Jean E. Ryser, Hans Blattmann, Peter Bläuenstein, Olivier Gardelle
Publikováno v:
Nuclear Medicine and Biology. 28:51-57
5-bromodeoxyuridine (BUdR) provides in vitro measures of tumor cell proliferation. We used positron emission tomography to study tissue and plasma kinetics of [76Br]BUdR in tumor-bearing animals. In order to account for the slow washout of the major
Publikováno v:
Coordination Chemistry Reviews. :901-919
A review on the synthesis and properties of the organometallic aqua-ion [M(OH2)3(CO)3]+ (M=Re, 99Tc, 99mTc), as relevant for radiopharmaceutical application, is presented. These important starting compounds can be prepared quantitatively, (a) on the
Publikováno v:
Applied Radiation and Isotopes. 44:645-649
A detailed and improved synthetic procedure to produce NCA 6-[ 18 F]fluoro- l -dopa (6-FDOPA) is described. A remotely-operable system for its routine production was built and tested for stable and reproducible tracer production ( n > 20). Commercial
Autor:
R. Visentin, R. Rossin, August P. Schubiger, Kirstin Ortner, Ulderico Mazzi, Roger Alberto, Roger Schibli
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:S510-S512
The synthesis of Re(I) and 99Tc(I) tricarbonyls complexes has been performed with a new phosphine containing tridentate chelator. Characterization of the complexes showed different coordinative patterns (POO, PNS and PO). All the obtained products we