Zobrazeno 1 - 10
of 16
pro vyhledávání: '"August George"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 4, p e1011059 (2023)
Multistep protein-protein interactions underlie most biological processes, but their characterization through methods such as isothermal titration calorimetry (ITC) is largely confined to simple models that provide little information on the intermedi
Externí odkaz:
https://doaj.org/article/70b777818987425fb8fcc7cc30f83b38
A systems-biology approach to molecular machines: Exploration of alternative transporter mechanisms.
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1007884 (2020)
Motivated by growing evidence for pathway heterogeneity and alternative functions of molecular machines, we demonstrate a computational approach for investigating two questions: (1) Are there multiple mechanisms (state-space pathways) by which a mach
Externí odkaz:
https://doaj.org/article/c19780301eb447ddbea3ed8c0c65fe35
Autor:
Paola Bisignano, Michael A Lee, August George, Daniel M Zuckerman, Michael Grabe, John M Rosenberg
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1007789 (2020)
Membrane transport is generally thought to occur via an alternating access mechanism in which the transporter adopts at least two states, accessible from two different sides of the membrane to exchange substrates from the extracellular environment an
Externí odkaz:
https://doaj.org/article/8e548db78b314bef88a8ef4d85ce8354
Publikováno v:
Protein Science. 32
In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases for refinem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ff1f45dc2075c67d30132a2c8eebae
https://doi.org/10.1002/pro.4538
https://doi.org/10.1002/pro.4538
Autor:
Jeremy Copperman, Shelby Santos, John Russo, Ogechukwu Ezenwa, August George, Daniel Zuckerman
Over the last two summers, we offered a week-long online class to high school students introducing Python computer programming and science careers in academia and beyond. With ~$100/student budget, we provided computing or experimental hardware to ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70f46fbf97df2098b07fd795ab7cc2d
https://doi.org/10.31219/osf.io/azf58
https://doi.org/10.31219/osf.io/azf58
Multistep protein-protein interactions underlie most biological processes, but their characterization through methods such as isothermal titration calorimetry (ITC) is largely confined to simple models that provide little information on the intermedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beb1b2449e8f6dfc11185404a18c4ddb
https://doi.org/10.1101/2022.06.29.498022
https://doi.org/10.1101/2022.06.29.498022
Autor:
August George, Daniel M. Zuckerman
Publikováno v:
Biophysical Journal. 122:284a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0583204925dd9bf7fa9dc1946d15b6ba
https://doi.org/10.1016/j.bpj.2022.11.1614
https://doi.org/10.1016/j.bpj.2022.11.1614
Autor:
Michael A. Lee, Michael Grabe, Daniel M. Zuckerman, August George, Paola Bisignano, John M. Rosenberg
Publikováno v:
PLoS computational biology, vol 16, iss 7
PLoS Computational Biology, Vol 16, Iss 7, p e1007789 (2020)
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 7, p e1007789 (2020)
PLoS Computational Biology
Membrane transport is generally thought to occur via an alternating access mechanism in which the transporter adopts at least two states, accessible from two different sides of the membrane to exchange substrates from the extracellular environment an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968c5b1a175f7e1a3536c2408bb07bd5
https://escholarship.org/uc/item/1p02p3sn
https://escholarship.org/uc/item/1p02p3sn
Publikováno v:
Biophysical Journal. 120:85a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15af76b687af6f4e3e3e449c4cd558a1
https://doi.org/10.1016/j.bpj.2020.11.723
https://doi.org/10.1016/j.bpj.2020.11.723
Publikováno v:
PLoS computational biology, vol 16, iss 7
PLoS Computational Biology, Vol 16, Iss 7, p e1007884 (2020)
PLoS Computational Biology, Vol 16, Iss 7, p e1007884 (2020)
Motivated by growing evidence for pathway heterogeneity and alternative functions of molecular machines, we demonstrate a computational approach for investigating two questions: (1) Are there multiple mechanisms (state-space pathways) by which a mach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb0425f340e804d4ebc1bb868d790b5
https://doi.org/10.1371/journal.pcbi.1007884
https://doi.org/10.1371/journal.pcbi.1007884