Human cytomegalovirus mediates APOBEC3B relocalization early during infection through a ribonucleotide reductase-independent mechanism.

Autor: Fanunza E; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio , San Antonio, Texas, USA.; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato , Cagilari, Italy., Cheng AZ; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota , Minneapolis, Minnesota, USA., Auerbach AA; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio , San Antonio, Texas, USA., Stefanovska B; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio , San Antonio, Texas, USA.; Howard Hughes Medical Institute, University of Texas Health San Antonio , San Antonio, Texas, USA., Moraes SN; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota , Minneapolis, Minnesota, USA., Lokensgard JR; Department of Medicine, University of Minnesota , Minneapolis, Minnesota, USA., Biolatti M; Department of Public Health and Pediatric Sciences, University of Turin , Turin, Italy., Dell'Oste V; Department of Public Health and Pediatric Sciences, University of Turin , Turin, Italy., Bierle CJ; Department of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, University of Minnesota , Minneapolis, Minnesota, USA., Bresnahan WA; Department of Microbiology and Immunology, University of Minnesota , Minneapolis, Minnesota, USA., Harris RS; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio , San Antonio, Texas, USA.; Howard Hughes Medical Institute, University of Texas Health San Antonio , San Antonio, Texas, USA.

Publikováno v: Journal of virology [J Virol] 2023 Aug 31; Vol. 97 (8), pp. e0078123. Date of Electronic Publication: 2023 Aug 11.

APOBEC3B drives PKR-mediated translation shutdown and protects stress granules in response to viral infection.

Autor: Manjunath L; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Oh S; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Ortega P; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Bouin A; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Department of Microbiology & Molecular Genetics, School of Medicine, University of California Irvine, Irvine, CA, USA., Bournique E; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Sanchez A; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA.; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Martensen PM; Department of Molecular Biology and Genetics, Aarhus University, Aarhus C, Denmark., Auerbach AA; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, TX, USA.; Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN, USA., Becker JT; Institute for Molecular Virology, University of Minnesota - Twin Cities, Minneapolis, MN, USA.; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota - Twin Cities, Minneapolis, MN, USA., Seldin M; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA., Harris RS; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, TX, USA.; Howard Hughes Medical Institute, University of Texas Health San Antonio, San Antonio, TX, USA., Semler BL; Center for Virus Research, University of California Irvine, Irvine, CA, USA.; Department of Microbiology & Molecular Genetics, School of Medicine, University of California Irvine, Irvine, CA, USA., Buisson R; Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA, USA. rbuisson@uci.edu.; Center for Virus Research, University of California Irvine, Irvine, CA, USA. rbuisson@uci.edu.; Center for Epigenetics and Metabolism, Chao Family Comprehensive Cancer Center, University of California Irvine, Irvine, CA, USA. rbuisson@uci.edu.; Department of Pharmaceutical Sciences, School of Pharmacy & Pharmaceutical Sciences, University of California Irvine, Irvine, CA, USA. rbuisson@uci.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Feb 14; Vol. 14 (1), pp. 820. Date of Electronic Publication: 2023 Feb 14.

Evidence linking APOBEC3B genesis and evolution of innate immune antagonism by gamma-herpesvirus ribonucleotide reductases.

Autor: Moraes SN; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States., Becker JT; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States., Moghadasi SA; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States., Shaban NM; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States., Auerbach AA; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States.; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, United States., Cheng AZ; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States., Harris RS; Department of Biochemistry, Molecular Biology, and Biophysics, Institute for Molecular Virology, Masonic Cancer Center, University of Minnesota, Minneapolis, United States.; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, United States.; Howard Hughes Medical Institute, University of Texas Health San Antonio, San Antonio, United States.

Publikováno v: ELife [Elife] 2022 Dec 02; Vol. 11. Date of Electronic Publication: 2022 Dec 02.

Autodiagnostic Pacemaker*

Autor: Furman S, Auerbach Aa

Publikováno v: Pacing and Clinical Electrophysiology. 2:58-68

Loss of normal pacemaker stimulation and/or sensing functions requires prompt detection, automatic correction, and automatic and continuous "marking" of the intermittent failure. The autodiagnostic pacemaker (ADP) detects "failure to capture" (FC) by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::050ff8241a86908026eed1ba1fe3193a
https://doi.org/10.1111/j.1540-8159.1979.tb05177.x

Investing in the future: building an academic hospitalist faculty development program.

Autor: Sehgal NL; Division of Hospital Medicine, University of California, San Francisco, San Francisco, California 94143, USA. nirajs@medicine.ucsf.edu, Sharpe BA, Auerbach AA, Wachter RM

Publikováno v: Journal of hospital medicine [J Hosp Med] 2011 Mar; Vol. 6 (3), pp. 161-6.