Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Audrys G. Pauza"'
Publikováno v:
Experimental Physiology, Vol 108, Iss 5, Pp 661-671 (2023)
Abstract The maintenance of glucose homeostasis is obligatory for health and survival. It relies on peripheral glucose sensing and signalling between the brain and peripheral organs via hormonal and neural responses that restore euglycaemia. Failure
Externí odkaz:
https://doaj.org/article/509894924c1846baaa3d9750d0bbd56d
Autor:
Paolo Contessotto, Renza Spelat, Federico Ferro, Vaidas Vysockas, Aušra Krivickienė, Chunsheng Jin, Sandrine Chantepie, Clizia Chinello, Audrys G. Pauza, Camilla Valente, Mindaugas Rackauskas, Alvise Casara, Vilma Zigmantaitė, Fulvio Magni, Dulce Papy-Garcia, Niclas G. Karlsson, Eglė Ereminienė, Abhay Pandit, Mark Da Costa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The study of the pathophysiology and possible interventions for non-ST-segment elevation myocardial infarction is hindered by the lack of a reproducible pre-clinical model. Here, authors develop an ovine model to reproduce post-ischemic remodeling in
Externí odkaz:
https://doaj.org/article/006423bd42ef408ab58fac9fefcc939e
Autor:
Olivia M. S. Gold, Emma N. Bardsley, Anna P. Ponnampalam, Audrys G. Pauza, Julian F. R. Paton
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
The carotid body is the primary peripheral chemoreceptor in the body, and critical for respiration and cardiovascular adjustments during hypoxia. Yet considerable evidence now implicates the carotid body as a multimodal sensor, mediating the chemoref
Externí odkaz:
https://doaj.org/article/a35802775aa34334ab0e7038d68b2044
Publikováno v:
American Journal of Physiology-Cell Physiology. 321:C826-C845
Thrombospondins (TSPs) are multidomain, secreted proteins that associate with cell surfaces and extracellular matrix. In mammals, there is a large body of data on functional roles of various TSP family members in cardiovascular disease (CVD), includi
Autor:
Soledad Bárez-López, André S. Mecawi, Natasha Bryan, Benjamin T. Gillard, Audrys G. Pauza, David Murphy, Michael P. Greenwood
The cell bodies of hypothalamic magnocellular neurones are densely packed in the hypothalamic supraoptic nucleus (SON) whereas their axons project to the anatomically discrete posterior pituitary gland. We have taken advantage of this unique anatomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7500d0aa351cdf7e73a3e7cc1d497de0
https://doi.org/10.1101/2022.05.31.494122
https://doi.org/10.1101/2022.05.31.494122
Autor:
Paolo Contessotto, Renza Spelat, Vaidas Vysockas, Aušra Krivickienė, Chunsheng Jin, Sandrine Chantepie, Clizia Chinello, Audrys G. Pauza, Mindaugas Rackauskas, Vilma Zigmantaitė, Fulvio Magni, Dulce Papy-Garcia, Niclas G. Karlsson, Eglė Ereminienė, Abhay Pandit, Mark Da Costa
The rising incidence of non-ST-segment elevation myocardial infarction (NSTEMI) and associated long-term high mortality constitutes an urgent clinical issue. Unfortunately, the study of possible interventions to treat this pathology lacks a reproduci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3deb611f2d4a7e5113f2b2b66eb82ce4
https://doi.org/10.1101/2022.05.19.492645
https://doi.org/10.1101/2022.05.19.492645
Autor:
Audrys G. Pauza, Pratik Thakkar, Tatjana Tasic, Igor Felippe, Paul Bishop, Michael P. Greenwood, Kristina Rysevaite-Kyguoliene, Julia Ast, Johannes Broichhagen, David J. Hodson, Helio C. Salgado, Dainius H. Pauza, Nina Japundzic-Zigon, Julian F.R. Paton, David Murphy
Publikováno v:
Circulation Research
Circ Res
Circ Res
Background: Aberrant sympathetic nerve activity exacerbates cardiovascular risk in hypertension and diabetes, which are common comorbidities, yet clinically sympathetic nerve activity remains poorly controlled. The hypertensive diabetic state is asso
Autor:
Matthew T. Birnie, Alex Paterson, Diana A. Stavreva, YM Kershaw, Becky L. Conway-Campbell, Audrys G Pauza, Songjoon Baek, David Murphy, Mark F. Rogers, Benjamin P. Flynn, Sohyoung Kim, Gordon L. Hager, Stafford L. Lightman
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009737 (2021)
Flynn, B P, Birnie, M T, Kershaw, Y M, Pauza, A G, Kim, S, Baek, S, Rogers, M F, Paterson, A R, Stavreva, D A, Murphy, D, Hager, G L, Lightman, S L & Conway-Campbell, B L 2021, ' Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver ', PLoS Genetics, vol. 17, no. 8, e1009737, pp. e1009737 . https://doi.org/10.1371/journal.pgen.1009737
PLoS Genetics
Flynn, B P, Birnie, M T, Kershaw, Y M, Pauza, A G, Kim, S, Baek, S, Rogers, M F, Paterson, A R, Stavreva, D A, Murphy, D, Hager, G L, Lightman, S L & Conway-Campbell, B L 2021, ' Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver ', PLoS Genetics, vol. 17, no. 8, e1009737, pp. e1009737 . https://doi.org/10.1371/journal.pgen.1009737
PLoS Genetics
Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynam
Publikováno v:
The FASEB Journal. 35
Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease
Autor:
JI Lukosiene, Neringa Pauziene, Kristina Rysevaite-Kyguoliene, Mantas Malinauskas, Algimantas Tamelis, Zilvinas Saladzinskas, Juozas Kupcinskas, Paulius Alaburda, Audrys G Pauza, Edgaras Stankevičius
Publikováno v:
Autonomic Neuroscience. 216:63-71
Diverticular disease (DD) is one of the most prevalent diseases of the large bowel. Lately, imbalance of neuro-muscular transmission has been recognized as a major etiological factor for DD. Neuronal calcitonin gene-related peptide (CGRP) is a potent