Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Audry Fernández"'
Autor:
Scott I Abrams, Audry Fernández, Liliana Oliver, Rydell Alvarez, Leslie Pérez, Circe Mesa, Kevin H Eng, Raquel Diaz, Anet Valdés, Sean H Colligan, Michael J Nemeth, Danielle Y F Twum, Olivia Fernández-Medina, Louise M Carlson, Han Yu, Mary L Hensen, Maura L Rábade-Chediak, Luis Enrique Fernández, Kelvin P Lee, Jason B Muhitch
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Immune suppression is common in neoplasia and a major driver is tumor-induced myeloid dysfunction. Yet, overcoming such myeloid cell defects remains an untapped strategy to reverse suppression and improve host defense. Exposure of bone mar
Externí odkaz:
https://doaj.org/article/47e829035a71457082f388bc215f48d3
Autor:
Amaury, Pupo, Audry, Fernández, Siew Hui, Low, Achille, François, Lester, Suárez-Amarán, Richard Jude, Samulski
Publikováno v:
Molecular Therapy. 30:3515-3541
Defective genes account for ∼80% of the total of more than 7,000 diseases known to date. Gene therapy brings the promise of a one-time treatment option that will fix the errors in patient genetic coding. Recombinant viruses are highly efficient veh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db09e1e92a8841aa7c84df9ec274b2af
https://doi.org/10.1016/j.ymthe.2022.09.015
https://doi.org/10.1016/j.ymthe.2022.09.015
Autor:
Catarina V. Nogueira, Rady J. Laborde, Yoelys Cruz-Leal, M. C. Luzardo, Darren E. Higgins, Lianne Abreu-Butin, Daniel Grubaugh, Audry Fernández, Ieda Maria Longo-Maugéri, Circe Mesa, Fabiola Pazos, María E. Lanio, Luis E. Fernández, Michael N. Starnbach, Mayari Eika Ishimura, Carlos Alvarez, María E. Alonso
Publikováno v:
Molecular Immunology. 131:144-154
Sticholysins (Sts) I and II (StI and StII) are pore-forming proteins (PFPs), purified from the Caribbean Sea anemone Stichodactyla helianthus. StII encapsulated into liposomes induces a robust antigen-specific cytotoxic CD8+ T lymphocytes (CTL) respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc6e326aff264a56b8da67d237bc4da
https://doi.org/10.1016/j.molimm.2020.12.032
https://doi.org/10.1016/j.molimm.2020.12.032
Autor:
Liliana Oliver, Rydell Alvarez, Raquel Diaz, Anet Valdés, Sean H Colligan, Michael J Nemeth, Danielle Y F Twum, Audry Fernández, Olivia Fernández-Medina, Louise M Carlson, Han Yu, Kevin H Eng, Mary L Hensen, Maura L Rábade-Chediak, Luis Enrique Fernández, Kelvin P Lee, Leslie Perez, Jason B Muhitch, Circe Mesa, Scott I Abrams
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004710
BackgroundImmune suppression is common in neoplasia and a major driver is tumor-induced myeloid dysfunction. Yet, overcoming such myeloid cell defects remains an untapped strategy to reverse suppression and improve host defense. Exposure of bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89665126bf3fdb4cd27ce8344f3ea69
https://doi.org/10.1136/jitc-2022-004710
https://doi.org/10.1136/jitc-2022-004710
Autor:
Ieda Maria Longo-Maugéri, Michael N. Starnbach, M. C. Luzardo, Oraly Sanchez-Ferras, Carlos Alvarez, Catarina V. Nogueira, Fabiola Pazos, Circe Mesa, María E. Alonso, Audry Fernández, Liliana Oliver, Liane Abreu-Butin, Rady J. Laborde, Yoelys Cruz-Leal, Mayra Tejuca, Liem Canet, Darren E. Higgins, Luis E. Fernández, María E. Lanio
Publikováno v:
The Journal of Immunology. 198:2772-2784
Vaccine strategies to enhance CD8+ CTL responses remain a current challenge because they should overcome the plasmatic and endosomal membranes for favoring exogenous Ag access to the cytosol of APCs. As a way to avoid this hurdle, sticholysin (St) II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded422239023b63dc879341f7a3df978
https://doi.org/10.4049/jimmunol.1600310
https://doi.org/10.4049/jimmunol.1600310
Publikováno v:
Molecular pharmacology. 90(3)
The pharmacological modulation of the immunosuppressive tumor microenvironment has emerged as a relevant component for cancer therapy. Several approaches aiming to deplete innate and adaptive suppressive populations, to circumvent the impairment in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbe4700745134b067bb892580f324a6
https://pubmed.ncbi.nlm.nih.gov/27260771
https://pubmed.ncbi.nlm.nih.gov/27260771
Autor:
Audry Fernández, Circe Mesa, Alejandro López-Requena, Judith Raymond, Liliana Oliver, Luis E. Fernández
Publikováno v:
Vaccine. 30:2963-2972
Leukopenia is a severe condition resulting from both pathological processes and some treatments, like chemotherapy in cancer patients. However, the activation of the patient immune system is required for the success of immunotherapeutic strategies, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1724839950dd5a71f7bbb03faf313d
https://doi.org/10.1016/j.vaccine.2012.02.054
https://doi.org/10.1016/j.vaccine.2012.02.054
Publikováno v:
Cancer Immunology, Immunotherapy. 57:1771-1780
Preventive immunotherapy is an attractive strategy for patients at a high risk of having cancer. The success of prophylactic cancer vaccines would depend on the selection of target antigens that are essential for tumour growth and progression. The ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b4d3d91286ddcf66e5057c248c83d3
https://doi.org/10.1007/s00262-008-0503-8
https://doi.org/10.1007/s00262-008-0503-8
Autor:
Mayrel Labrada, Audry Fernández, Marilyn Clavell, Circe Mesa, Luis E. Fernández, Joel de León, Yanin Bebelagua
Publikováno v:
International Immunology. 20:591-600
Increasing evidences suggest that the aberrant expression of certain gangliosides on malignant cells could affect host's anti-tumour-specific immune responses. We have recently documented the relevance of the N-glycolylated variant of GM3 ganglioside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ae80dd2c1d8199a1f72fea7b1cdc4a
https://doi.org/10.1093/intimm/dxn018
https://doi.org/10.1093/intimm/dxn018
Autor:
Audry Fernández, Luis E. Fernández, Rydell Alvarez, Kelvin P. Lee, Liliana Oliver, Circe Mesa
Publikováno v:
Human vaccinesimmunotherapeutics. 10(11)
Adjuvants are a critical but largely overlooked and poorly understood component included in vaccine formulations to stimulate and modulate the desired immune responses to an antigen. However, unlike in the protective infectious disease vaccines, adju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8380f088980dfeb544418367b1f810c
https://pubmed.ncbi.nlm.nih.gov/25483674
https://pubmed.ncbi.nlm.nih.gov/25483674