Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Audrius Paskevicius"'
Autor:
Martin Bender, Jan-Michael Abicht, Bruno Reichart, Maria Leuschen, Felicia Wall, Julia Radan, Elisabeth Neumann, Maren Mokelke, Ines Buttgereit, Sebastian Michel, Reinhard Ellgass, Katja Gieseke, Stig Steen, Audrius Paskevicius, Joachim Denner, Antonia W. Godehardt, Ralf R. Tönjes, Christian Hagl, David Ayares, Eckhard Wolf, Michael Schmoeckel, Paolo Brenner, Martin B. Müller, Matthias Längin
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1336 (2024)
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation. Despite these achievements, acute vascular rejection still presents a challenge for long-t
Externí odkaz:
https://doaj.org/article/c841e0d47f65460a97bd17080a2ace3d
Autor:
Johan Nilsson, Victoria Jernryd, Guangqi Qin, Audrius Paskevicius, Carsten Metzsch, Trygve Sjöberg, Stig Steen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Ischemia and reperfusion damage contribute to early graft dysfunction and recipient’s death. Here the authors show the feasibility and safety of a non-ischemic heart preservation method for heart transplantation in a non-randomized trial.
Externí odkaz:
https://doaj.org/article/f39aecfe4ca9407ca1f37c429ffaeb07
Publikováno v:
Artificial organs. 46(9)
Existing working heart models for ex vivo functional evaluation of donor hearts often use cardiac afterloads made up of discrete resistive and compliant elements. This approach limits the practicality of independently controlling systolic and diastol
Autor:
Victoria Jernryd, Johan Nilsson, Trygve Sjöberg, Carsten Metzsch, Stig Steen, Audrius Paskevicius, Guangqi Qin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications
Nature Communications
Pre-clinical heart transplantation studies have shown that ex vivo non-ischemic heart preservation (NIHP) can be safely used for 24 h. Here we perform a prospective, open-label, non-randomized phase II study comparing NIHP to static cold preservation
Autor:
Qiuming Liao, Paolo Brenner, Peter J. Murray, Bruno Reichart, Andrea Bähr, Julia Radan, Eckhard Wolf, Ines Buttgereit, Reinhard Ellgass, Barbara Kessler, Riccardo Sfriso, David Ayares, Anastasia Milusev, Tanja Mayr, Alessandro Panelli, Maren Mokelke, Jan-Michael Abicht, Nikolai Klymiuk, Audrius Paskevicius, Stefanie Egerer, Stig Steen, Robert Rieben, Lara Issl, Trygve Sjöberg, Guangqi Qin, Jiawei Ying, Matthias Längin, Ann Kathrin Fresch, Christoph Walz
Publikováno v:
Längin, Matthias; Reichart, Bruno; Steen, Stig; Sjöberg, Trygve; Paskevicius, Audrius; Liao, Qiuming; Qin, Guangqi; Mokelke, Maren; Mayr, Tanja; Radan, Julia; Issl, Lara; Buttgereit, Ines; Ying, Jiawei; Fresch, Ann Kathrin; Panelli, Alessandro; Egerer, Stefanie; Bähr, Andrea; Kessler, Barbara; Milusev, Anastasia; Sfriso, Riccardo; ... (2021). Cold non-ischemic heart preservation with continuous perfusion prevents early graft failure in orthotopic pig-to-baboon xenotransplantation. Xenotransplantation, 28(1), e12636. Wiley 10.1111/xen.12636
Xenotransplantation
Xenotransplantation
BACKGROUND Successful preclinical transplantations of porcine hearts into baboon recipients are required before commencing clinical trials. Despite years of research, over half of the orthotopic cardiac xenografts were lost during the first 48 hours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea2449e73c6eaf561cbf2e9e41fa137
Autor:
Reinhard Ellgass, Uwe Fiebig, Andrea Baehr, Audrius Paskevicius, Stig Steen, Mayuko Kurome, Julia Radan, Ralf R. Tönjes, Robert Rieben, Lara Issl, Barbara Kessler, Riccardo Sfriso, Jan-Michael Abicht, Trygve Sjöberg, Sebastian Michel, Thomas Kirchner, Christoph Walz, David Ayares, Luise Krüger, Paolo Brenner, Anastasia Milusev, Tanja Mayr, Christian Hagl, Uwe Schönmann, Bruno Reichart, Jiawei Ying, Matthias Längin, Antonia W. Godehardt, Ann Kathrin Fresch, Stefanie Egerer, Ines Buttgereit, Stefan Buchholz, Joachim Denner, Maren Mokelke, Elisabeth Kemter, Nikolai Klymiuk, Maks Mihalj, Karen Lampe, Valeri Zakhartchenko, Eckhard Wolf
Background The demand for donated human hearts far exceeds the number available. Xenotransplantation of genetically modified porcine organs provides an alternative. In 2000, an Advisory Board of the International Society for Heart and Lung Transplant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b180c54125324bd9aeaa0bff516bfdc1
Publikováno v:
ACC
First responders to cardiac arrest depend on cardiopulmonary resuscitation to keep patients alive. A new ventilation method, phase-controlled intermittent insufflation of oxygen, was previously shown to improve heart perfusion during cardiopulmonary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa710bde31f77e28b75a06511dd996b
https://lup.lub.lu.se/record/8bc2d1dd-3233-40cc-ba34-83ec2bf04b26
https://lup.lub.lu.se/record/8bc2d1dd-3233-40cc-ba34-83ec2bf04b26
Publikováno v:
Resuscitation; 138, pp 215-215 (2019)
Purpose: It has previously been shown that continuous intratracheal insufflation of oxygen (CIO) is superior to intermittent positive pressure ventilation (IPPV) regarding gas exchange and haemodynamics. The purpose of this study was to investigate g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa89bdadc9f84ee32c08f03096913bb9
https://lup.lub.lu.se/record/d2176bd0-da22-4f2e-ac08-da76b9190fef
https://lup.lub.lu.se/record/d2176bd0-da22-4f2e-ac08-da76b9190fef
Autor:
Fabian Werner, Robert Rieben, Günter Wich, Alexey Dashkevich, Trygve Sjöberg, Nikolai Klymiuk, Uli Binder, David Ayares, Maren Mokelke, Andrea Baehr, Elisabeth Kemter, Liao Qiuming, Christian Kupatt, Paolo Brenner, Julia Radan, Maks Mihalj, Alessandro Panelli, Stefan Buchholz, Simone Reu, Sebastian Michel, Almuth Falkenau, Barbara Kessler, Rabea Hinkel, Sonja Guethoff, Stefanie Egerer, Ines Buttgereit, Alexander Kind, Riccardo Sfriso, I. Lutzmann, Rudolf Herzog, Maik Dahlhoff, Lara Issl, Stig Steen, Bruno Reichart, Mayuko Kurome, Valeri Zakhartchenko, Matthias Längin, Ann Kathrin Fresch, Katharina Klett, Christian Hagl, Eckhard Wolf, Jan-Michael Abicht, Andreas Bauer, Franz-Josef Kaup, Reinhard Ellgass, Tanja Mayr, Uwe Schönmann, Arne Skerra, Audrius Paskevicius, Jiawei Ying
Publikováno v:
Nature. 564(7736)
Heart transplantation is the only cure for patients with terminal cardiac failure, but the supply of allogeneic donor organs falls far short of the clinical need1–3. Xenotransplantation of genetically modified pig hearts has been discussed as a pot
Autor:
Qiuming Liao, Kristian Soltesz, Christopher Sturk, Guangqi Qin, Audrius Paskevicius, Trygve Sjöberg, Stig Steen
Publikováno v:
IEEE Transactions on Biomedical Engineering; 64(6), pp 1310-1317 (2017)
Objective: The purpose of this paper is to demonstrate feasibility of a novel closed-loop controlled therapy for prevention of hypertension in the heartbeating brain-dead porcine model. Methods: Dynamic modeling and system identification were based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb6c1c271337e4a2700400b3046cc0b
https://lup.lub.lu.se/record/8eedfc3a-db98-460e-a110-eba027353d16
https://lup.lub.lu.se/record/8eedfc3a-db98-460e-a110-eba027353d16