Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Audrey Zarba"'
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Protective Alterations in Phase 1 and 2 Metabolism of Aflatoxin B1 by Oltipraz in Residents of Qidong, People's Republic of China
Autor: Geng Sun Qian, Lisa P. Jacobson, Audrey Zarba, Patricia A. Egner, Jia-Sheng Wang, Alvaro Muñoz, Thomas W. Kensler, Yuan Rog Zhu, John D. Groopman, Xia He, Bao Chu Zhang, Xinnan Shen, Shuang Yuan Kuang, Jin Bing Wang, Katy J. Helzlsouer
Publikováno v: JNCI Journal of the National Cancer Institute. 91:347-354
Background: Residents of Qidong, People’s Republic of China, are at high risk for development of hepatocellular carcinoma, in part due to consumption of foods contaminated with aflatoxins, which require metabolic activation to become carcinogenic.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2015e445cfdf7e9aa7b2ea4205c394
https://doi.org/10.1093/jnci/91.4.347
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4
Respiratory Aflatoxicosis: Suppression of Pulmonary and Systemic Host Defenses in Rats and Mice
Autor: George J. Jakab, Audrey Zarba, David R. Hemenway, Robert R. Hmieleski, John D. Groopman
Publikováno v: Toxicology and Applied Pharmacology. 125:198-205
Dietary aflatoxin B 1 (AFB 1 ) exposure impairs innate and acquired host defenses resulting in increased susceptibility to infections in domesticated animals. Experimental studies have confirmed this observation by demonstrating the immunosuppressive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1355f48538da7910f35c9270097ed5
https://doi.org/10.1006/taap.1994.1065
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6
Elevated HPRT mutation frequencies in aflatoxin-exposed residents of daxin, Qidong county, People's Republic of China
Autor: Haroutune K. Armenian, Yu Rong Zhu, Geng Sun Qian, Jia Bin Wang, Neal F. Cariello, James A. Swenberg, Sophia S. Wang, John D. Groopman, Audrey Zarba, Jia-Sheng Wang, Thomas W. Kensler, J. Patrick O'Neill
Publikováno v: Carcinogenesis. 20(11)
Molecular biomarkers are becoming increasingly important tools to identify people who are at highest risk of developing cancer. For many years we have been studying residents of Qidong County, People's Republic of China, to examine the combined impac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380210676e59420543e86058156711f5
https://pubmed.ncbi.nlm.nih.gov/10545423
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8
Aflatoxin B1--DNA adduct formation in rat liver following exposure by aerosol inhalation
Autor: John D. Groopman, George J. Jakab, Robert Himieleski, David R. Hemenway, Audrey Zarba
Publikováno v: Carcinogenesis. 13(6)
There is growing concern that human exposure to respirable grain dust contaminated with aflatoxin B1 (AFB1), a potent hepatocarcinogen, may be a risk factor for a number of human diseases. The objective of this study was to determine if liver DNA add
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88657559d56e3c36df33b75a36d821a
https://pubmed.ncbi.nlm.nih.gov/1600607
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9
Aflatoxin M1 in human breast milk from The Gambia, west Africa, quantified by combined monoclonal antibody immunoaffinity chromatography and HPLC
Autor: Andrew J. Hall, Audrey Zarba, Ruggero Montesano, John D. Groopman, Geoffrey J. Hudson, Christopher P. Wild
Publikováno v: Carcinogenesis. 13(5)
Maternal to child exposure of aflatoxin M1 in breast milk is an underevaluated risk factor from dietary exposure to aflatoxin B1. A molecular dosimetry study in The Gambia, West Africa, was initiated to explore the relationships between dietary intak
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf70ac8e5545fc2c57bd6e26a1055d05
https://pubmed.ncbi.nlm.nih.gov/1587004
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