Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Audrey Tze Ting Khoo"'
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract The defining features of a neuron are its functional and anatomical connections with thousands of other neurons in the brain. Together, these neurons form functional networks that direct animal behavior. Current approaches that allow the int
Externí odkaz:
https://doaj.org/article/3dd3740f5b3a435f9e49bebc190327f7
Autor:
Alfred Xuyang Sun, Qiang Yuan, Shawn Tan, Yixin Xiao, Danlei Wang, Audrey Tze Ting Khoo, Levena Sani, Hoang-Dai Tran, Paul Kim, Yong Seng Chiew, Kea Joo Lee, Yi-Chun Yen, Huck Hui Ng, Bing Lim, Hyunsoo Shawn Je
Publikováno v:
Cell Reports, Vol 16, Iss 7, Pp 1942-1953 (2016)
Gamma-aminobutyric acid (GABA)-releasing interneurons play an important modulatory role in the cortex and have been implicated in multiple neurological disorders. Patient-derived interneurons could provide a foundation for studying the pathogenesis o
Externí odkaz:
https://doaj.org/article/091f2fb94fb34db09bbe7c3f12c0d72b
Autor:
Hidayat Lokman, Huck-Hui Ng, Audrey Tze Ting Khoo, Wei-Yi Ong, Junghyun Jo, Grace Lim, Hoang Dai Tran, Seung-Jae Lee, Weonjin Yu, Lin Yang, Lai Ping Yaw, Ya Yin Chang, Jessica Jiaxin Xie, Kah-Leong Lim, Bin Xiao, Eng-King Tan, Tzuen Yih Saw, Byung Chul Jung, Alfred Xuyang Sun, Hyunsoo Shawn Je
Publikováno v:
Annals of neurology. 90(3)
Objective: We utilized human midbrain-like organoids (hMLOs) generated from human pluripotent stem cells carrying glucocerebrosidase gene (GBA1) and α-synuclein (α-syn; SNCA) perturbations to investigate genotype-to-phenotype relationships in Parki
Autor:
Florent Ginhoux, Jin-Soo Kim, Young-Tae Chang, Aymeric Silvin, Sungjin Park, H. Shawn Je, Masahiro Fukuda, Audrey Tze Ting Khoo, Xiao Liu, Beomsue Kim, Sejong Choi, Taejoon Kwon, Jungyeol Lee, Xiaogang Liu, Dongdong Su, Weijie Chi, Diana S. Y. Wan, Srikanta Sanu
Publikováno v:
Angewandte Chemie International Edition. 58:7972-7976
Microglia, the brain-resident macrophage, are involved in brain development and contribute to the progression of neural disorders. Despite the importance of microglia, imaging of live microglia at a cellular resolution has been limited to transgenic
Publikováno v:
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-10 (2020)
Molecular Brain, Vol 13, Iss 1, Pp 1-10 (2020)
The defining features of a neuron are its functional and anatomical connections with thousands of other neurons in the brain. Together, these neurons form functional networks that direct animal behaviour. Current approaches that allow the interrogati
Autor:
Audrey Tze Ting Khoo, Jungyeol Lee, Aymeric Silvin, H. Shawn Je, Beomsue Kim, Sungjin Park, Xiaogang Liu, Taejoon Kwon, Masahiro Fukuda, Xiao Liu, Weijie Chi, Dongdong Su, Sejong Choi, Diana S. Y. Wan, Florent Ginhoux, Srikanta Sanu, Young-Tae Chang, Jin-Soo Kim
Publikováno v:
Angewandte Chemie International Edition. 58
Publikováno v:
Behavioral Neuroscience. 129:2-7
The ventral pallidum (VP) is a key component of the neural circuitry mediating relapse to drug seeking, but the critical afferent pathways to VP recruited during relapse remain poorly understood. We studied the role of the nucleus accumbens core (Acb
Autor:
Levana L. Sani, Hoang-Dai Tran, Shawn Tan, Danlei Wang, Kea Joo Lee, Paul Jong Kim, Qiang Yuan, Huck-Hui Ng, Hyunsoo Shawn Je, Yi-Chun Yen, Yixin Xiao, Alfred Xuyang Sun, Bing Lim, Yong Seng Chiew, Audrey Tze Ting Khoo
Publikováno v:
Cell Reports, Vol 16, Iss 7, Pp 1942-1953 (2016)
SummaryGamma-aminobutyric acid (GABA)-releasing interneurons play an important modulatory role in the cortex and have been implicated in multiple neurological disorders. Patient-derived interneurons could provide a foundation for studying the pathoge