The genus Polygonum: An updated comprehensive review of its ethnomedicinal, phytochemical, pharmacological activities, toxicology, and phytopharmaceutical formulation

Autor: Sourour Idoudi, Audrey Tourrette, Jalloul Bouajila, Mehrez Romdhane, Walid Elfalleh

Publikováno v: Heliyon, Vol 10, Iss 8, Pp e28947- (2024)

Polygonum is a plant genus that includes annual and perennial species and is found at various temperatures, from northern temperate regions to tropical and subtropical areas. The genus Polygonum has been used for centuries for various disorders, incl

Externí odkaz: https://doaj.org/article/1a18606cc66c4d35bc15a21afe0cbf87

The antioxidant 2,3‐dichloro,5,8‐dihydroxy,1,4‐naphthoquinone inhibits acetyl‐cholinesterase activity and amyloid β 42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease

Autor: El Akrem Hayouni, Jalloul Bouajila, Zohra Dhouafli, Sara Abdelfatah, Imen Khelifi, Audrey Tourrette, Thomas Efferth, Riadh Ksouri

Publikováno v: Biotechnology and Applied Biochemistry. 67:983-990

Alzheimer's disease is characterized by amyloid β aggregation and cholinergic neurodegeneration. In the present study, pure DDN (2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone) was examined, for the first time, for its dual potential as inhibitor of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e575b1675298e8f648e9c71a37ca2f3c
https://doi.org/10.1002/bab.1870

A deeper insight into the dual temperature- and pH-responsiveness of poly(vinylamine)-b-poly(N-isopropylacrylamide) double hydrophilic block copolymers

Autor: Clémence Nadal, Stéphane Gineste, Olivier Coutelier, Audrey Tourrette, Jean-Daniel Marty, Mathias Destarac

Publikováno v: Colloids and Surfaces A: Physicochemical and Engineering Aspects
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022, 641, pp.128502. ⟨10.1016/j.colsurfa.2022.128502⟩

International audience; Block copolymers based on poly(vinylamine) and poly(N-isopropylacrylamide), PVAmm-b-PNIPAMn, were synthetized by hydrazinolysis of poly(N-vinylphthalimide) based copolymers, PVPIm-b-PNIPAMn, obtained by RAFT polymerization. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1967e694b4ffa38bf9d1c5183849b34
https://hal.science/hal-03565568/document

In Vitro and In Silico Studies of Two 1,4-Naphthoquinones and Their Topical Formulation in Bigels

Autor: Imen Khelifi, Riadh Ksouri, Audrey Tourrette, Thomas Efferth, El Akrem Hayouni, Daycem Khelifi, Jalloul Bouajila

Publikováno v: Current drug delivery. 18(7)

Background: 1,4-Naphthoquinones (1,4-NQs) are secondary plant metabolites with numerous biological activities. 1,4-NQs display low water solubility and poor bioavailability. Bigels are a new technology with great potential, which are designated as dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2b9076e36cd32c4e09706280165049
https://pubmed.ncbi.nlm.nih.gov/34145994

Surface functionalization of plasticized chitosan films through PNIPAM grafting via UV and plasma graft polymerization

Autor: Guillaume Conzatti, Rino Morent, Nathalie De Geyter, Sandrine Cavalie, Shaan Chamary, Audrey Tourrette

Publikováno v: European Polymer Journal
European Polymer Journal, Elsevier, 2018, 105, pp.434-441. ⟨10.1016/j.eurpolymj.2018.06.020⟩

International audience; Chitosan films were formulated and subsequently given thermosensitive properties by modifying the surfaces. The first step involved the incorporation of poly(ethylene glycol) (PEG) plasticizers at various ratios into the chito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93211370fb3225cc0209586e4739b6a6
https://doi.org/10.1016/j.eurpolymj.2018.06.020