Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Audrey Mole"'
Autor:
Christiane Jungels, Véronique Trochon-Joseph, Carlos Gomez-Roca, Jean-Pierre Delord, Anne Vincent-Salomon, Nuria Kotecki, Olga Adamiec, Wael Jdey, Philippe A. Cassier, Christophe Le Tourneau, Christelle Zandanel, Edith Borcoman, Hélène Toussaint, Audrey Mole, Lauriane Eberst, Vincent Cockenpot, Ségolène Hescot, Olivier de Beaumont, Françoise Bono
Publikováno v:
British Journal of Cancer
BackgroundAsiDNA, a first-in-class oligonucleotide-mimicking double-stranded DNA breaks, acts as a decoy agonist to DNA damage response in tumour cells. It also activates DNA-dependent protein kinase and poly (adenosine diphosphate [ADP]-ribose) poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6ac8c5643740222554ee9e7cff0352
https://doi.org/10.1038/s41416-020-01028-8
https://doi.org/10.1038/s41416-020-01028-8
Autor:
Hélène Toussaint, Nuria Kotecki, Olivier de Beaumont, Jean-Pierre Delord, Olga Adamiec, Edith Borcoman, Christophe Le Tourneau, Ségolène Hescot, Audrey Mole, Philippe A. Cassier, Christiane Jungels
Publikováno v:
Molecular Cancer Therapeutics. 18:A076-A076
Background: AsiDNA is a first-in-class oligonucleotide that mimics double-stranded DNA breaks and acts as a decoy to disrupt the DNA damage response at the “real” sites of DNA damage. It also activates the DNA-PK and PARP enzymes that induce the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dbcad336be671c0bbc61852a44d574e
https://doi.org/10.1158/1535-7163.targ-19-a076
https://doi.org/10.1158/1535-7163.targ-19-a076