Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Audrey Low"'
Autor:
Ingrid Buller-Peralta, Sarah Gregory, Audrey Low, Maria-Eleni Dounavi, Katie Bridgeman, Georgios Ntailianis, Brian Lawlor, Lorina Naci, Ivan Koychev, Paresh Malhotra, John T. O’Brien, Craig W. Ritchie, Graciela Muniz-Terrera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To date, there is a considerable heterogeneity of methods to score Allostatic Load (AL). Here we propose a comprehensive algorithm (ALCS) that integrates commonly used approaches to generate AL risk categories and assess associations to brai
Externí odkaz:
https://doaj.org/article/ccb535da1f184e7a9790aaf75a87d94a
Autor:
Roy P C Kessels, Audrey Low, Hugh Markus, Anil Tuladhar, Frank‐Erik de Leeuw, Robin G Morris, Ziad Mallat, Niels P Riksen, Daniel J Tozer, Sanne van Winden, Lupei Cai, Marnix C Maas, Meritxell Nus, Anja van der Kolk, Rowan Wolters
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction The INflammation and Small Vessel Disease (INSVD) study aims to investigate whether peripheral inflammation, immune (dys)regulation and blood–brain barrier (BBB) permeability relate to disease progression in cerebral small vessel disea
Externí odkaz:
https://doaj.org/article/9de6a34a9f7443a3934e4e2d8c33f96d
Autor:
Audrey Low, Maria A Prats-Sedano, James D Stefaniak, Elizabeth McKiernan, Stephen F Carter, Maria-Eleni Dounavi, Elijah Mak, Li Su, Olivia Stupart, Graciela Muniz-Terrera, Karen Ritchie, Craig W Ritchie, Hugh S Markus, John T O'Brien
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100050- (2024)
Externí odkaz:
https://doaj.org/article/de9bf992c4b34557b34ad62e53015ba2
Autor:
Audrey Low, Maria A. Prats-Sedano, Elizabeth McKiernan, Stephen F. Carter, James D. Stefaniak, Stefania Nannoni, Li Su, Maria-Eleni Dounavi, Graciela Muniz-Terrera, Karen Ritchie, Brian Lawlor, Lorina Naci, Paresh Malhotra, Clare Mackay, Ivan Koychev, Craig W. Ritchie, Hugh S. Markus, John T. O’Brien
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Considerable overlap exists between the risk factors of dementia and cerebral small vessel disease (SVD). However, studies remain limited to older cohorts wherein pathologies of both dementia (e.g. amyloid) and SVD (e.g. white mat
Externí odkaz:
https://doaj.org/article/818fa79205274e5c84710a0024322785
Autor:
Audrey Low, Elijah Mak, Maura Malpetti, Leonidas Chouliaras, Nicolas Nicastro, Li Su, Negin Holland, Timothy Rittman, Patricia Vázquez Rodríguez, Luca Passamonti, W Richard Bevan‐Jones, PP Simon Jones, James B. Rowe, John T. O'Brien
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 690-699 (2019)
Abstract Introduction Although widespread cortical asymmetries have been identified in Alzheimer's disease (AD), thalamic asymmetries and their relevance to clinical severity in AD remain unclear. Methods Lateralization indices were computed for indi
Externí odkaz:
https://doaj.org/article/2453552f94744ec78af5f01efc8e2b40
Autor:
Elijah Mak, Maria-Eleni Dounavi, Audrey Low, Stephen F. Carter, Elizabeth McKiernan, Guy B Williams, P Simon Jones, Isabelle Carriere, Graciela Terrera Muniz, Karen Ritchie, Craig Ritchie, Li Su, John T O'Brien
Publikováno v:
NeuroImage, Vol 229, Iss , Pp 117749- (2021)
Background: First-degree relatives of people with dementia (FH+) are at increased risk of developing Alzheimer's disease (AD). Here, we investigate “estimated years to onset of dementia” (EYO) as a surrogate marker of preclinical disease progress
Externí odkaz:
https://doaj.org/article/975141c19ad14ad38061ecab31ae2174
Autor:
Carla Casu, Alison Liu, Gianluca De Rosa, Audrey Low, Aae Suzuki, Sayantani Sinha, Yelena Z. Ginzburg, Charles Abrams, Mariam Aghajan, Shuling Guo, Stefano Rivella
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Polycythemia Vera (PV) is a chronic myeloproliferative neoplasm resulting from an acquired driver mutation in the JAK2 gene of hematopoietic stem and progenitor cells resulting in the overproduction of mature erythrocytes and abnormally high hematocr
Externí odkaz:
https://doaj.org/article/9ba25bee8a6941e696e2191e45a8d141
Autor:
Audrey Low, Elijah Mak, James D. Stefaniak, Maura Malpetti, Nicolas Nicastro, George Savulich, Leonidas Chouliaras, Hugh S. Markus, James B. Rowe, John T. O’Brien
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
BackgroundThe peak width of skeletonized mean diffusivity (PSMD) has been proposed as a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We assessed PSMD in relation to conventional SVD markers, global measures of n
Externí odkaz:
https://doaj.org/article/c6db892f90a548be873e9c7ed014c661
Autor:
Lulu Huang, Audrey Low, Sagar S. Damle, Melissa M. Keenan, Steven Kuntz, Susan F. Murray, Brett P. Monia, Shuling Guo
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background About 11% of all human genetic diseases are caused by nonsense mutations that generate premature translation termination codons (PTCs) in messenger RNAs (mRNA). PTCs not only lead to the production of truncated proteins, but also
Externí odkaz:
https://doaj.org/article/8ab099ebcff244beb8bcc89c1831c531
Autor:
Andrew P. Lieberman, Zhigang Yu, Sue Murray, Raechel Peralta, Audrey Low, Shuling Guo, Xing Xian Yu, Constanza J. Cortes, C. Frank Bennett, Brett P. Monia, Albert R. La Spada, Gene Hung
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 774-784 (2014)
Spinal and bulbar muscular atrophy (SBMA) is caused by the polyglutamine androgen receptor (polyQ-AR), a protein expressed by both lower motor neurons and skeletal muscle. Although viewed as a motor neuronopathy, data from patients and mouse models s
Externí odkaz:
https://doaj.org/article/362a686dbe4b43e48c2719a1d0ab43eb