RCPred: RNA complex prediction as a constrained maximum weight clique problem

Autor: Audrey Legendre, Eric Angel, Fariza Tahi

Publikováno v: BMC Bioinformatics, Vol 20, Iss S3, Pp 53-62 (2019)

Abstract Background RNAs can interact and form complexes, which have various biological roles. The secondary structure prediction of those complexes is a first step towards the identification of their 3D structure. We propose an original approach tha

Externí odkaz: https://doaj.org/article/6d2b11512f1f4b6fa6046a54972e7221

Multigenerational Exposure to Uranium Changes Sperm Metabolome in Rats

Autor: Stéphane Grison, Audrey Legendre, Ljubica Svilar, Christelle Elie, Dimitri Kereselidze, Céline Gloaguen, Philippe Lestaevel, Jean-Charles Martin, Maâmar Souidi

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (15), pp.8349. ⟨10.3390/ijms23158349⟩
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8349

International audience; Male infertility is a major public health issue that can be induced by a host of lifestyle risk factors such as environment, nutrition, smoking, stress, and endocrine disruptors. Regarding the human population exposed to urani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576c6c2c2aaaedecdbf1144121b4a94d
https://doi.org/10.3390/ijms23158349

Co-exposure to internal and external radiation alters cesium biokinetics and retention in mice

Autor: Victor Magneron, David Broggio, Karine Tack, Jean-Marc Bertho, Raphaël Bo, Audrey Legendre, Margaux Cochard

Publikováno v: Journal of Radiological Protection
Journal of Radiological Protection, IOP Publishing, 2020, pp.504-519. ⟨10.1088/1361-6498/ab7b43⟩

Exposures in post-accidental situations are complex and include both external exposure and internal contamination with several radionuclides. However, in vivo and in vitro studies generally use simplified exposures, while a recent study suggested tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddc814a684b45ec6c7bebe042f83260
https://hal.archives-ouvertes.fr/hal-02869303/file/0000161353_002.PDF

In vivoanimal studies help achieve international consensus on standards and guidelines for health risk estimates for chronic exposure to low levels of tritium in drinking water

Autor: Julie Leblanc, Christelle Durand, Karine Tack, Marc Benderitter, Sandrine Roch-Lefèvre, Audrey Legendre, Laurence Roy, Philippe Lestaevel, Eric Gregoire, Nicholas D. Priest, Chrystelle Ibanez, Isabelle Dublineau, Teni Ebrahimian, Yann Gueguen, Laura A Bannister, Jean-René Jourdain, Heather Wyatt, Stéphane Grison, Dmitry Klokov

Publikováno v: Environmental and Molecular Mutagenesis. 59:586-594

Existing and future nuclear fusion technologies involve the production and use of large quantities of tritium, a highly volatile, but low toxicity beta-emitting isotope of hydrogen. Tritium has received international attention because of public and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0149840e7efad6bafb6f214d4e889bb
https://doi.org/10.1002/em.22200

Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: Metabolomics and gene expression study

Autor: Eric Leclerc, Guillaume Tcherkez, Rachid Jellali, Marie José Fleury, Audrey Legendre, Sébastien Jacques, Perrine Zeller, Françoise Gilard

Publikováno v: Environmental Toxicology and Pharmacology
Environmental Toxicology and Pharmacology, Elsevier, 2018, 59, pp.1-12. ⟨10.1016/j.etap.2018.02.004⟩

International audience; Dichlorodiphenyl-trichloroethane (DDT) and permethrin (PMT) are amongst most prevalent pesticides in the environment. Although their toxicity has been extensively studied, molecular mechanisms and metabolic effects remain uncl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7f1c3c87f7bf31291a1a63a5b9ecf9
https://doi.org/10.1016/j.etap.2018.02.004