Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Audrey Laroche"'
Publikováno v:
Cancer Communications, Vol 43, Iss 3, Pp 391-394 (2023)
Externí odkaz:
https://doaj.org/article/92230db00f0747dcba1a72a8c4316b19
Autor:
Benjamin Fourneaux, Aurélien Bourdon, Bérengère Dadone, Carlo Lucchesi, Scott R. Daigle, Elodie Richard, Audrey Laroche-Clary, François Le Loarer, Antoine Italiano
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background Leiomyosarcoma (LMS) is one of the most frequent soft tissue sarcoma subtypes and is characterized by a consistent deregulation of the PI3K/mTOR pathway. Cancer stem cells (CSCs) have been poorly studied in soft tissue sarcomas. I
Externí odkaz:
https://doaj.org/article/baa3e9b084fc41328ab4c41e9f8692ff
Autor:
Maud Toulmonde, Carlo Lucchesi, Stéphanie Verbeke, Amandine Crombe, Julien Adam, Damien Geneste, Vanessa Chaire, Audrey Laroche-Clary, Raul Perret, François Bertucci, Frederic Bertolo, Laurence Bianchini, Bérengère Dadone-Montaudie, Todd Hembrough, Steve Sweet, Yeoun Jin Kim, Fabiola Cecchi, François Le Loarer, Antoine Italiano
Publikováno v:
EBioMedicine, Vol 62, Iss , Pp 103131- (2020)
Background: Undifferentiated pleomorphic sarcoma (UPS) is the most frequent, aggressive and less-characterized sarcoma subtype. This study aims to assess UPS molecular characteristics and identify specific therapeutic targets. Methods: High-throughpu
Externí odkaz:
https://doaj.org/article/0185fa0580fe4a78a9027ab7a57a448a
Autor:
Audrey Laroche-Clary, Vanessa Chaire, Marie-Paule Algeo, Marie-Alix Derieppe, François L. Loarer, Antoine Italiano
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-10 (2017)
Abstract Purpose MDM2 and CDK4 are frequently co-amplified in well-differentiated/dedifferentiated liposarcoma (WDLPS/DDLPS). We aimed to determine whether combined MDM2/CDK4 targeting is associated with higher antitumour activity than a single agent
Externí odkaz:
https://doaj.org/article/d565165539b94e5fab3f124b61aa7b7e
Autor:
Audrey Laroche, Vanessa Chaire, François Le Loarer, Marie-Paule Algéo, Christophe Rey, Kevin Tran, Carlo Lucchesi, Antoine Italiano
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-10 (2017)
Abstract Background Trabectedin has recently been approved in the USA and in Europe for advanced soft-tissue sarcoma patients who have been treated with anthracycline-based chemotherapy without success. The mechanism of action of trabectedin depends
Externí odkaz:
https://doaj.org/article/c18ec359c7674082bab0a82356b5d0bf
Autor:
Benjamin Fourneaux, Aurélien Bourdon, Bérengère Dadone, Carlo Lucchesi, Scott R. Daigle, Elodie Richard, Audrey Laroche-Clary, François Le Loarer, Antoine Italiano
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-1 (2019)
The Editor-in-Chief would like to alert readers that the ownership of some of the data presented in this article [1]
Externí odkaz:
https://doaj.org/article/21c4e7a38d6b4776a62c2a63a155f8bd
Autor:
Audrey Laroche, Kevin Tran-Cong, Vanessa Chaire, Pauline Lagarde, Isabelle Hostein, Jean-Michel Coindre, Frederic Chibon, Agnes Neuville, Tom Lesluyes, Carlo Lucchesi, Antoine Italiano
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0137794 (2015)
Nutlin inhibits TP53-MDM2 interaction and is under investigation in soft-tissue sarcomas (STS) and other malignancies. Molecular mechanisms of secondary resistance to nutlin in STS are unknown. We performed whole-transcriptome sequencing (RNA-seq) on
Externí odkaz:
https://doaj.org/article/a598f0172ac0428580201b2b16c1f32b
Cytochrome P450 1B1 (CYP1B1) is found in tumor tissue and is suspected to play a role in oncogenesis and drug resistance. CYP1B1 gene polymorphisms have been associated with the risk of developing lung and other cancers. They may be associated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6412173389554a13a54072254b20a1b3
https://doi.org/10.1158/1535-7163.c.6536700.v1
https://doi.org/10.1158/1535-7163.c.6536700.v1
Supplementary Data from Cytochrome P450 1B1 Gene Polymorphisms as Predictors of Anticancer Drug Activity: Studies with In vitro Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3291d4fba418a6e86cccfa889c97677
https://doi.org/10.1158/1535-7163.22501179.v1
https://doi.org/10.1158/1535-7163.22501179.v1
Autor:
Amandine Crombe, Carlo Lucchesi, Frédéric Bertolo, Michèle Kind, Raul Perret, Francois Le Loarer, Mariella Spalato-Ceruso, Maud Toulmonde, Audrey Laroche, Vanessa Chaire, Aurelien Bourdon, Antoine Italiano
Publikováno v:
Cancer Research. 83:5435-5435
Introduction: STS are mostly prognosticated through nomograms relying on age, size, histotype and grade. Radiomics approaches, complemented with deep-learning, deep-radiomics and gene-expression profiling, could help understanding the bridge between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::937fe84be08296ca68189a2cc5b9b2e6
https://doi.org/10.1158/1538-7445.am2023-5435
https://doi.org/10.1158/1538-7445.am2023-5435