Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Audrey Lang"'
Autor:
Tadatoshi Sato, Shiv Verma, Christian D. Castro Andrade, Maureen Omeara, Nia Campbell, Jialiang S. Wang, Murat Cetinbas, Audrey Lang, Brandon J. Ausk, Daniel J. Brooks, Ruslan I. Sadreyev, Henry M. Kronenberg, David Lagares, Yuhei Uda, Paola Divieti Pajevic, Mary L. Bouxsein, Ted S. Gross, Marc N. Wein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Osteocytes are mechanoresponsive within skeletal tissue. Here, the authors show that class IIa histone deacetylases are phosphorylated by focal adhesion kinase, suggesting that HDAC5 may propagate mechanobiological cues to regulate cell type-specific
Externí odkaz:
https://doaj.org/article/28efc06b6072451db15433775595a921
Autor:
Paola Divieti Pajevic, Ruslan I. Sadreyev, Yuhei Uda, Audrey Lang, Shiv K. Verma, Maureen J O'Meara, Jialiang S. Wang, Ted S. Gross, Nia Campbell, Henry M. Kronenberg, Mary L. Bouxsein, Tadatoshi Sato, Brandon J. Ausk, Murat Cetinbas, Christian D. Castro Andrade, Marc N. Wein, David Lagares, Daniel J. Brooks
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Osteocytes, cells ensconced within mineralized bone matrix, are the primary skeletal mechanosensors. Osteocytes sense mechanical cues by changes in fluid flow shear stress (FFSS) across their dendritic projections. Loading-induced reductions of osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979529c4e7bdfa6fcb4bcef1e9de7bcc
http://link.springer.com/article/10.1038/s41467-020-17099-3
http://link.springer.com/article/10.1038/s41467-020-17099-3
Autor:
Bradford C. Dickerson, Surya A. Reis, Krista M. Hennig, Angela She, Audrey Lang, Wen-Ning Zhao, Joachim Herz, Ralph Mazitschek, Iren Kurtser, Jenny Lai, Stephen J. Haggarty
Publikováno v:
Cell chemical biology. 24(7)
Frontotemporal dementia (FTD) arises from neurodegeneration in the frontal, insular, and anterior temporal lobes. Autosomal dominant causes of FTD include heterozygous mutations in the GRN gene causing haploinsufficiency of progranulin (PGRN) protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461cab7592a229faaeaa5ba840aa90be
https://pubmed.ncbi.nlm.nih.gov/28712747
https://pubmed.ncbi.nlm.nih.gov/28712747
Autor:
Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 11, Pp 1471-1481 (2017)
Abstract Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known. Peroxisome proliferator activato
Externí odkaz:
https://doaj.org/article/41d9acc15de04a65b09a64e46554e7da
Autor:
Anthony Martin Mena, Audrey Langlois, Silvia Speca, Lucil Schneider, Pierre Desreumaux, Laurent Dubuquoy, Benjamin Bertin
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The etiology of inflammatory bowel diseases remains largely unknown. We previously demonstrated that the expression of the peroxisome proliferator activated receptor-gamma (PPARγ) is downregulated in colonic epithelial cells of patients with ulcerat
Externí odkaz:
https://doaj.org/article/f1561832e36a452ab559612f4931128f
Autor:
Muriel Montbarbon, Muriel Pichavant, Audrey Langlois, Edmone Erdual, François Maggiotto, Christel Neut, Thierry Mallevaey, Sébastien Dharancy, Laurent Dubuquoy, François Trottein, Antoine Cortot, Pierre Desreumaux, Philippe Gosset, Benjamin Bertin
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62208 (2013)
Cigarette smoke (CS) protects against intestinal inflammation during ulcerative colitis. Immunoregulatory mechanisms sustaining this effect remain unknown. The aim of this study was to assess the effects of CS on experimental colitis and to character
Externí odkaz:
https://doaj.org/article/001f3796374648b1956ebcf27154f550