Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Audrey L. Muggleton-Harris"'
Autor:
Audrey L. Muggleton-Harris
Publikováno v:
Growth Control During Cell Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4f6e06262e9caea61f1400bfd4dc67
https://doi.org/10.1201/9781003068150-20
https://doi.org/10.1201/9781003068150-20
Publikováno v:
Human Reproduction. 10:1021-1029
Human embryos have been biopsied at either the cleavage or the blastocyst stage of development. One to two blastomeres were removed from cleavage-stage embryos and 2-6 cells from blastocysts. The biopsy specimens were subjected to gene amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52410ba9bdd0c4fda9e2cd67c9605f8c
https://doi.org/10.1093/oxfordjournals.humrep.a136028
https://doi.org/10.1093/oxfordjournals.humrep.a136028
Publikováno v:
Molecular Human Reproduction. 1:101-109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dab12a93763595808c275bb7c6f5a013
https://doi.org/10.1093/molehr/1.2.101
https://doi.org/10.1093/molehr/1.2.101
Publikováno v:
Current Opinion in Obstetrics and Gynecology. 5:600-605
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c349cc636bc22bc4610d661e48bb3289
https://doi.org/10.1097/00001703-199310000-00004
https://doi.org/10.1097/00001703-199310000-00004
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1097:81-85
Cloned cDNAs coding for eye-lens fibre cell-membrane proteins, MIP and MP70, were used to detect restriction fragment length polymorphisms (RFLPs) in genomic DNA from inbred mice with autosomally inherited cataracts. Whereas distinct RFLPs associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a585a19a8363e69f190ebc1c22a6526
https://doi.org/10.1016/0925-4439(91)90028-8
https://doi.org/10.1016/0925-4439(91)90028-8
Autor:
I. Findlay, Audrey L. Muggleton-Harris
Publikováno v:
Human Reproduction. 6:85-92
Methods previously used for the biopsy of preimplantation mouse embryos have been applied to individual 'spare' human embryos. Early cleavage-stage human embryos have been cultured and individual blastomeres removed following zonae thinning or drilli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2073c9f40c51bc6950ab3f8d09d79505
https://doi.org/10.1093/oxfordjournals.humrep.a137264
https://doi.org/10.1093/oxfordjournals.humrep.a137264
Autor:
Audrey L. Muggleton-Harris, David G. Whittingham, Leroy Hood, Christopher M. Gomez, Carol Readhead
Publikováno v:
Proceedings of the National Academy of Sciences. 87:4481-4484
As a model for the detection of human genetic disease in preimplantation embryos, we describe a method in which trophectoderm biopsy samples from viable mouse blastocysts are simultaneously analyzed for the presence of a normal or mutant allele of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9643e8a6939629006318eb751afe2ac
https://doi.org/10.1073/pnas.87.12.4481
https://doi.org/10.1073/pnas.87.12.4481
Publikováno v:
Human Reproduction. 5:217-220
The culture of human preimplantation embryos from the 1-cell to the morula/blastocyst stage of development is not satisfactory at present. The success of various IVF laboratories ranges from 18 to 23%, therefore there is a requirement for improvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af528e565e57ce5c8b2b644cfe4ce84
https://doi.org/10.1093/oxfordjournals.humrep.a137073
https://doi.org/10.1093/oxfordjournals.humrep.a137073
Publikováno v:
Issues in Fetal Medicine ISBN: 9781349238149
A number of diseases are genetic, that is to say inherited (Milunsky, 1986). Some of these will manifest themselves early in childhood resulting in severe physical and mental handicap, and sometimes in the demise of the child before its teens. Many c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8262456b7a6cf518a5c5cb1b1ea58f08
https://doi.org/10.1007/978-1-349-23812-5_4
https://doi.org/10.1007/978-1-349-23812-5_4
Autor:
Audrey L. Muggleton-Harris
Publisher Summary Recent advances in recombinant DNA technology have led to rapid progress in the characterization of mutations and chromosome aberrations, which give rise to genetic diseases. Since the development of amniocentesis and chorionic vill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95504597ab88c0fb6fdca964ac870cfe
https://doi.org/10.1016/s0074-7696(08)62629-7
https://doi.org/10.1016/s0074-7696(08)62629-7