Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Audrey K. O'Neill"'
Autor:
Terren K. Niethamer, Andrew R. Larson, Audrey K. O’Neill, Marina Bershteyn, Edward C. Hsiao, Ophir D. Klein, Jason H. Pomerantz, Jeffrey O. Bush
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 529-537 (2017)
Although human induced pluripotent stem cells (hiPSCs) hold great potential for the study of human diseases affecting disparate cell types, they have been underutilized in seeking mechanistic insights into the pathogenesis of congenital craniofacial
Externí odkaz:
https://doaj.org/article/fd30d514e8f0484a83b89035b904b324
Autor:
Terren K. Niethamer, Audrey K. O’Neill, Jeffrey O. Bush, Andrew R. Larson, Hsin-Yi Henry Ho, Abigail A. Kindberg, Michael E. Greenberg
Publikováno v:
The Journal of cell biology, vol 215, iss 2
The Journal of Cell Biology
The Journal of Cell Biology
Eph/ephrins drive cell segregation and boundary formation. O’Neill et al. discover that segregation is driven by unidirectional kinase-dependent EphB signaling. Unidirectional signaling generates a cortical actin differential between ephrin-B1– a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a6303d6d91ca03987c89406a4e6752
https://doi.org/10.1083/jcb.201604097
https://doi.org/10.1083/jcb.201604097
Autor:
Jeffrey O. Bush, Audrey K. O’Neill
Publikováno v:
Epstein's Inborn Errors of Development: The Molecular Basis of Clinical Disorders of Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8824d173027fc12675158a282048f4db
https://doi.org/10.1093/med/9780199934522.003.0086
https://doi.org/10.1093/med/9780199934522.003.0086
Publikováno v:
FEBS Journal. 280:572-583
The recently discovered pleckstrin homology (PH) domain leucine-rich repeat protein phosphatase (PHLPP) family is emerging as a central component in suppressing cell survival pathways. Originally discovered in a rational search for a phosphatase that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4f3edfbdf267bcf618a662ba398822
https://doi.org/10.1111/j.1742-4658.2012.08537.x
https://doi.org/10.1111/j.1742-4658.2012.08537.x
Publikováno v:
Journal of Neurochemistry. 100:1340-1350
Biosynthesis of peptide hormones and neurotransmittters involves proteolysis of proprotein precursors by secretory vesicle cathepsin L. Cathepsin L generates peptide intermediates with basic residues at their NH2-termini, indicating that Arg/Lys amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927274ed3ef351af82ac1d00a8ae1a4f
https://doi.org/10.1111/j.1471-4159.2006.04325.x
https://doi.org/10.1111/j.1471-4159.2006.04325.x
Publikováno v:
Developmental biology, vol 379, iss 2
The Wnt1-Cre transgenic mouse line is extensively used in the study of the development of the neural crest and its derivatives and the midbrain. The Wnt1 gene has important developmental roles in formation of the midbrain–hindbrain boundary, regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd592c35903c803b1a9bbea02b790d33
https://pubmed.ncbi.nlm.nih.gov/23648512
https://pubmed.ncbi.nlm.nih.gov/23648512
Publikováno v:
The FEBS journal. 280(2)
The recently discovered pleckstrin homology (PH) domain leucine-rich repeat protein phosphatase (PHLPP) family is emerging as a central component in suppressing cell survival pathways. Originally discovered in a rational search for a phosphatase that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27976e545b1bf95df197047273035a4b
https://pubmed.ncbi.nlm.nih.gov/22340730
https://pubmed.ncbi.nlm.nih.gov/22340730
Autor:
Natarajan Kannan, Hilde Abrahamsen, Audrey K. O’Neill, Susan S. Taylor, Nicole Kruse, Alexandra C. Newton, Patricia A. Jennings
Publikováno v:
The Journal of biological chemistry. 287(16)
The down-regulation or cellular depletion of protein kinase C (PKC) attendant to prolonged activation by phorbol esters is a widely described property of this key family of signaling enzymes. However, neither the mechanism of down-regulation nor whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f1e30bec3a7291cfd84b348d09ec92
https://pubmed.ncbi.nlm.nih.gov/22318721
https://pubmed.ncbi.nlm.nih.gov/22318721
Autor:
Audrey K. O’Neill, Alexandra C. Newton
Publikováno v:
Atlas of Genetics and Cytogenetics in Oncology and Haematology.
Review on PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2), with data on DNA, on the protein encoded, and where the gene is implicated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93ac45a8a1ddd56540097e5e3af4de5a
https://doi.org/10.4267/2042/44756
https://doi.org/10.4267/2042/44756
Autor:
Michael Leitges, Alan P. Fields, Lisa L. Gallegos, Verline Justilien, Erin L. Garcia, Audrey K. O’Neill, Randy A. Hall, Alexandra C. Newton
Publikováno v:
The Journal of biological chemistry. 286(50)
Protein scaffolds maintain precision in kinase signaling by coordinating kinases with components of specific signaling pathways. Such spatial segregation is particularly important in allowing specificity of signaling mediated by the 10-member family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ed477ddd28b021f549789aaaeeea2b
https://pubmed.ncbi.nlm.nih.gov/22027822
https://pubmed.ncbi.nlm.nih.gov/22027822