Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Audrey Jordaan"'
Autor:
Nosipho Cele, Paul Awolade, Pule Seboletswe, Lungisani Khubone, Kolawole Olofinsan, Md. Shahidul Islam, Audrey Jordaan, Digby F. Warner, Parvesh Singh
Publikováno v:
ChemistryOpen, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Two libraries of quinoline‐based hybrids 1‐(7‐chloroquinolin‐4‐yl)‐1H‐pyrazolo[3,4–d]pyrimidin‐4‐amine and 7‐chloro‐N‐phenylquinolin‐4‐amine were synthesized and evaluated for their α‐glucosidase inhibitory a
Externí odkaz:
https://doaj.org/article/8d47b8ac9082410195c81e8781270c6f
Autor:
Phelelisiwe S. Dube, Dylan Hart, Lesetja J. Legoabe, Audrey Jordaan, Digby F. Warner, Richard M. Beteck
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1793 (2024)
Nitrothiazole derivatives have been reported to exhibit activity against aerobic, anaerobic, and microaerophilic bacteria. This activity profile makes the nitrothiazole compound class an ideal lead source against Mycobacterium tuberculosis, which flo
Externí odkaz:
https://doaj.org/article/40c7ba286eb94060a2d26e116b07e4f3
Autor:
Erika Kapp, Jacques Joubert, Samantha L. Sampson, Digby F. Warner, Ronnett Seldon, Audrey Jordaan, Margaretha de Vos, Rajan Sharma, Sarel F. Malan
Publikováno v:
Advances in Pharmacological and Pharmaceutical Sciences, Vol 2021 (2021)
Mycobacterium tuberculosis has developed extensive resistance to numerous antimycobacterial agents used in the treatment of tuberculosis. Insufficient intracellular accumulation of active moieties allows for selective survival of mycobacteria with dr
Externí odkaz:
https://doaj.org/article/88c1c1f46efe44879b93b4033a581dc2
Autor:
Melissa D. Chengalroyen, Audrey Jordaan, Ronnett Seldon, Thomas Ioerger, Scott G. Franzblau, Mohamed Nasr, Digby F. Warner, Valerie Mizrahi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Compounds with novel modes of action are urgently needed to develop effective combination therapies for the treatment of tuberculosis. In this study, a series of compounds was evaluated for activity against replicating Mycobacterium tuberculosis and
Externí odkaz:
https://doaj.org/article/5d51bc9be63449abbabb4eac3d227c42
Autor:
Kojo Sekyi Acquah, Denzil R. Beukes, Ronnett Seldon, Audrey Jordaan, Suthananda N. Sunassee, Digby F. Warner, David W. Gammon
Publikováno v:
Medicines, Vol 9, Iss 2, p 9 (2022)
Tuberculosis (TB) remains a public health crisis, requiring the urgent identification of new anti-mycobacterial drugs. We screened several organic and aqueous marine invertebrate extracts for their in vitro inhibitory activity against the causative o
Externí odkaz:
https://doaj.org/article/de1fa207bf2b402a97761e4dc7922c0a
Autor:
Richard M. Beteck, Audrey Jordaan, Ronnett Seldon, Dustin Laming, Heinrich C. Hoppe, Digby F. Warner, Setshaba D. Khanye
Publikováno v:
Molecules, Vol 26, Iss 4, p 1141 (2021)
The cell wall of Mycobacterium tuberculosis (Mtb) has a unique structural organisation, comprising a high lipid content mixed with polysaccharides. This makes cell wall a formidable barrier impermeable to hydrophilic agents. In addition, during host
Externí odkaz:
https://doaj.org/article/b96ee633dccf4561a86ae61e3e0b43a1
Autor:
Kadidiatou O. Ndjoubi, Rajan Sharma, Jelili A. Badmus, Ayesha Jacobs, Audrey Jordaan, Jeanine Marnewick, Digby F. Warner, Ahmed A. Hussein
Publikováno v:
Plants, Vol 10, Iss 1, p 175 (2021)
Medicinal plants of the Plectranthus genus (Lamiaceae) are well known for their ethnomedicinal applications. Plectranthus madagascariensis, which is native to South Africa, is traditionally used in the treatment of respiratory conditions, scabies, an
Externí odkaz:
https://doaj.org/article/5d9c9a503e76487294622475fcde0c87
Autor:
Richard M. Beteck, Ronnett Seldon, Audrey Jordaan, Digby F. Warner, Heinrich C. Hoppe, Dustin Laming, Setshaba D. Khanye
Publikováno v:
Molecules, Vol 24, Iss 9, p 1740 (2019)
Co-infection of malaria and tuberculosis, although not thoroughly investigated, has been noted. With the increasing prevalence of tuberculosis in the African region, wherein malaria is endemic, it is intuitive to suggest that the probability of co-in
Externí odkaz:
https://doaj.org/article/1ef9d9e08e7d475cbea912cb415d3467
Autor:
Phelelisiwe S. Dube, Klaudia T. Angula, Lesetja J. Legoabe, Audrey Jordaan, Jan M. Boitz Zarella, Digby F. Warner, J. Stone Doggett, Richard M. Beteck
Publikováno v:
ACS Omega. 8:17086-17102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05681ded7546c5496bb8f8756d87a150
https://doi.org/10.1021/acsomega.3c01406
https://doi.org/10.1021/acsomega.3c01406
Autor:
Omobolanle Janet Jesumoroti, Richard M. Beteck, Audrey Jordaan, Digby F. Warner, Lesetja J. Legoabe
Publikováno v:
Molecular Diversity. 27:753-765
Tuberculosis (TB) is one of the leading causes of death worldwide. Developing new anti-TB compounds using cost-effective processes is critical to reduce TB incidence and accomplish the End TB Strategy milestone. Herein, we describe the synthesis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979d5fb0a97bd24b7cf85e76d9747180
https://doi.org/10.1007/s11030-022-10453-1
https://doi.org/10.1007/s11030-022-10453-1