Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Audrey J Lazenby"'
Autor:
Nina V Chaika, Fang Yu, Vinee Purohit, Kamiya Mehla, Audrey J Lazenby, Dominick DiMaio, Judy M Anderson, Jen Jen Yeh, Keith R Johnson, Michael A Hollingsworth, Pankaj K Singh
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32996 (2012)
Pancreatic cancer is the fourth leading cause of cancer related deaths in the United States with a five-year survival rate of 6%. It is characterized by extremely aggressive tumor growth rate and high incidence of metastasis. One of the most common a
Externí odkaz:
https://doaj.org/article/3d07d5aecc804eda98e4f8aa643653bf
Autor:
Jihao Xu, Jae‐Seok Roe, EunJung Lee, Claudia Tonelli, Keely Y. Ji, Omar W. Younis, Tim D.D. Somervile, Melissa Yao, Joseph P. Milazzo, Herve Tiriac, Anna M. Kolarzyk, Esak Lee, Jean L. Grem, Audrey J. Lazenby, James A. Grunkemeyer, Michael A. Hollingsworth, Paul M. Grandgenett, Alexander D. Borowsky, Youngkyu Park, Christopher R. Vakoc, David A. Tuveson, Chang‐Il Hwang
Publikováno v:
Advanced Science, Vol 11, Iss 6, Pp n/a-n/a (2024)
Abstract Engrailed‐1 (EN1) is a critical homeodomain transcription factor (TF) required for neuronal survival, and EN1 expression has been shown to promote aggressive forms of triple negative breast cancer. Here, it is reported that EN1 is aberrant
Externí odkaz:
https://doaj.org/article/fa247bd53d254f95b68bf57810402255
Autor:
Pinaki Mondal, Neesha S. Patel, Katie Bailey, Shruthishree Aravind, Sara B. Cartwright, Michael A. Hollingsworth, Audrey J. Lazenby, Mark A. Carlson
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/481684fb18ae4673b2205b6a20c578a1
Autor:
Neil Bhogal, Bernadette Lamb, Benjamin Arbeiter, Sarah Malik, Harlan Sayles, Audrey J. Lazenby, Saurabh Chandan, Amaninder Dhaliwal, Shailender Singh, Ishfaq Bhat
Publikováno v:
Endoscopy International Open, Vol 08, Iss 12, Pp E1850-E1854 (2020)
Background and study aims Endoscopic ultrasound-guided liver biopsy (EUS-LB) is an accepted technique for tissue acquisition. Traditionally, random LB has been performed with percutaneous (PC-LB) and transjugular (TJ-LB) approaches. The purpose of th
Externí odkaz:
https://doaj.org/article/87294792b3ae478c8509d7192d339df3
Autor:
Jihao Xu, Jae-Seok Roe, EunJung Lee, Claudia Tonelli, Tim D.D. Somerville, Melissa Yao, Joseph P. Milazzo, Herve Tiriac, Ania M. Kolarzyk, Esak Lee, Jean L. Grem, Audrey J. Lazenby, James A. Grunkemeyer, Michael A. Hollingsworth, Alexander D. Borowsky, Youngkyu Park, Christopher R. Vakoc, David A. Tuveson, Chang-Il Hwang
Engrailed-1(EN1) is a critical homeodomain transcription factor (TF) required for neuronal survival, and EN1 expression has been shown to promote aggressive forms of triple negative breast cancer. Here, we report thatEN1is aberrantly expressed in a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::429a701db16e0b62716b9912458a060e
https://doi.org/10.1101/2023.04.10.536259
https://doi.org/10.1101/2023.04.10.536259
Autor:
Jochen K. Lennerz, Liron Pantanowitz, Mitual B. Amin, Isam-Eldin Eltoum, Meera R. Hameed, Alexana N. Kalof, Elham Khanafshar, Lakshmi P. Kunju, Audrey J. Lazenby, Kathleen T. Montone, Christopher N. Otis, Michelle D. Reid, Paul N. Staats, Christa L. Whitney-Miller, Catherine S. Abendroth, Manju Aron, George G. Birdsong, Ira J. Bleiweiss, Mary P. Bronner, Jennifer Chapman, Nicole A. Cipriani, Gustavo de la Roza, Michael J. Esposito, Oluwole Fadare, Karen Ferrer, Christopher D. Fletcher, David P. Frishberg, Fernando U. Garcia, Laurette Geldenhuys, Ryan M. Gill, Dorina Gui, Shams Halat, Omar Hameed, Jason L. Hornick, Aaron R. Huber, Dhanpat Jain, Nirag Jhala, Merce Jorda, Julie M. Jorns, Jeffrey Kaplan, Mahmoud A. Khalifa, Ashraf Khan, Grace E. Kim, Eun Y. Lee, Virginia A. LiVolsi, Teri Longacre, Cristina Magi-Galluzzi, Shannon J. McCall, Laron McPhaul, Vikas Mehta, Mihai Merzianu, Stacey B. Miller, Kyle H. Molberg, Andre L. Moreira, Bita V. Naini, Vania Nosé, Kathleen O’Toole, Maria Picken, Victor G. Prieto, James M. Pullman, Charles M. Quick, Jordan P. Reynolds, Andrew E. Rosenberg, Stuart J. Schnitt, Mary R. Schwartz, Marin Sekosan, Michael T. Smith, Aliyah Sohani, Anne Stowman, Vijay K. Vanguri, Beverly Wang, John C. Watts, Shi Wei, Kathleen Whitney, Mamoun Younes, Sui Zee, Erika R. Bracamonte
Publikováno v:
Nature Medicine. 28:2453-2455
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2eda1dce3f942f91155887029de8834
https://doi.org/10.1038/s41591-022-02040-6
https://doi.org/10.1038/s41591-022-02040-6
Autor:
Ryan J. King, Surendra K. Shukla, Chunbo He, Enza Vernucci, Ravi Thakur, Kuldeep S. Attri, Aneesha Dasgupta, Nina V. Chaika, Scott E. Mulder, Jaime Abrego, Divya Murthy, Venugopal Gunda, Camila G. Pacheco, Paul M. Grandgenett, Audrey J. Lazenby, Michael A. Hollingsworth, Fang Yu, Kamiya Mehla, Pankaj K. Singh
Publikováno v:
Oncogene. 41:971-982
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae0dce488cdfbc65b01dce4e49232e21
https://doi.org/10.1038/s41388-021-02132-6
https://doi.org/10.1038/s41388-021-02132-6
Autor:
Pankaj K. Singh, Aaron R. Sasson, Jean Grem, Lyudmyla Berim, Audrey J. Lazenby, Fang Yu, Nina V. Chaika, Jaime Abrego, Enza Vernucci, Venugopal Gunda, Ryan J. King, Surendra K. Shukla, Saber Tadros
Figure S1: FASN inhibition with orlistat shows synergistic activity with gemcitabine in AsPC-1 cells; Figure S2: Effect of orlistat on the lipid content of pancreatic cancer cells; Figure S3: Platensimycin shows synergistic activity with gemcitabine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596cf661396a3ee8aaf765d72fe2857b
https://doi.org/10.1158/0008-5472.22414755
https://doi.org/10.1158/0008-5472.22414755
Autor:
Michael A. Hollingsworth, Fang Yu, Henrik Clausen, Ulla Mandel, Hans H. Wandall, Audrey J. Lazenby, Dominick J. DiMaio, Erin M. Linde, Judy M. Anderson, Neeley Remmers
PDF file - 248K, Supplementary Figure 1. (A) Simplified schematic of mucin type O-glycans analyzed in this report. Mucin-type O-linked glycans are initiated by the addition of an N-acetyl galactose sugar residue (the Tn epitope), which can be extende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda5a8d5fafc774d2ae3db3f1a30cc42
https://doi.org/10.1158/1078-0432.22452357
https://doi.org/10.1158/1078-0432.22452357
Autor:
Michael A. Hollingsworth, Fang Yu, Henrik Clausen, Ulla Mandel, Hans H. Wandall, Audrey J. Lazenby, Dominick J. DiMaio, Erin M. Linde, Judy M. Anderson, Neeley Remmers
Purpose: Mucin expression is a common feature of most adenocarcinomas and features prominently in current attempts to improve diagnosis and therapy for pancreatic cancer and other adenocarcinomas. We investigated the expression of a number of mucin c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bdcdf97bf11f49e52b5f36eac13a9ee
https://doi.org/10.1158/1078-0432.c.6522456
https://doi.org/10.1158/1078-0432.c.6522456