Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Audrey H. Lau"'
Autor:
Kosh Agarwal, Man-Fung Yuen, Heiner Wedemeyer, Daniel Cloutier, Ling Shen, Andre Arizpe, Sneha V. Gupta, Marie C. Fanget, Lillian Seu, Andrea Cathcart, Audrey H. Lau, Carey Hwang, Edward J Gane
Publikováno v:
Journal of Hepatology. 77:S831-S832
Autor:
Susanna K. Tan, John Ling, Polina German, Stephane Daffis, Ethan P Grant, Shyamasundaran Kottilil, Bhawna Poonia, Richard L Mackman, Tina Lam, Audrey H. Lau, Anita Mathias, Jacky Woo, Maribel Reyes, Peiwen Wu, Simon P. Fletcher, Edward Gane, Justin D. Lutz, Anuj Gaggar, Adarsh Joshi, Natarajan Ayithan
Publikováno v:
Antiviral therapy. 25(3)
Background Selgantolimod is a novel oral, selective Toll-like receptor 8 (TLR8) agonist in development for the treatment of chronic hepatitis B (CHB). TLR8 is an endosomal innate immune receptor and a target for treatment of viral infections. This fi
Autor:
Audrey H. Lau, Olivia M. Martinez, Megan B. Fitzpatrick, Benjamin A. Pinsky, Malaya K. Sahoo, Christine H. Yang
Publikováno v:
The Journal of Infectious Diseases. 220:361-369
BackgroundLiver failure of unknown etiology (LFUE) has a transplant-free survival rate MethodsWe identified all children who underwent liver transplant for LFUE at a single quaternary children’s hospital; 51/65 cases could be age matched with contr
Autor:
Yang Liu, G. Mani Subramanian, Seung Kew Yoon, Wan-Long Chuang, Kosh Agarwal, Henry Lik-Yuen Chan, Pietro Lampertico, Susanna K. Tan, Huy N. Trinh, Ho Bae, Scott Fung, Vithika Suri, John F. Flaherty, Alnoor Ramji, Edward Tam, Audrey H. Lau, Sang Hoon Ahn, George Wu, Xiaoli Ma, Maria Buti, Won Young Tak, Chi Yi Chen, Young-Suk Lim, Anuj Gaggar
Publikováno v:
The lancet. Gastroenterologyhepatology. 5(5)
Treatment with tenofovir disoproxil fumarate has been associated with renal toxicity or reductions in bone mineral density, or both, in some patients with chronic hepatitis B virus (HBV) infection. Tenofovir alafenamide is a tenofovir prodrug with hi
Autor:
Maciej Jabłkowski, John F. Flaherty, Maria Buti, Shuyuan Mo, Anuj Gaggar, Henry Lik-Yuen Chan, Fehmi Tabak, Jia-Horng Kao, Abhijit Chowdhury, Wan-Long Chuang, Elena Nurmukhametova, Young-Suk Lim, Audrey H. Lau, Scott Fung, Xiaoli Ma, Namiki Izumi, Edward Gane, Vithika Suri, Adrian Streinu-Cercel, Wai-Kay Seto
Publikováno v:
Clinical Hepatology.
Background TAF has shown efficacy non-inferior to that of TDF at Week 96 with less bone and renal effects. Following implementation of a protocol amendment to extend double-blind (DB) treatment for an additional year, 50% of patients were able to con
Autor:
Becket Feierbach, Kosh Agarwal, Young-Suk Lim, Seung Kew Yoon, Pietro Lampertico, John F. Flaherty, Wan-Long Chuang, Xiaoli Ma, Anuj Gaggar, Scott Fung, Henry Lik-Yuen Chan, Maria Buti, George Y. Wu, Sang Hoon Ahn, Huy N. Trinh, Edward Tam, Ho Bae, Chi-Yi Chen, Vithika Suri, Mani Subramanian, Alnoor Ramji, Audrey H. Lau, Won Young Tak
Publikováno v:
Clinical Hepatology.
Background TAF has shown efficacy non-inferior to TDF with improved renal and bone safety in viremic CHB patients at Weeks 48 and 96. We evaluated efficacy and safety in stable, virally-suppressed patients who were switched from TDF to TAF vs. contin
Autor:
Andrea Vecchi, Audrey H. Lau, Carolina Boni, Xiaoli Ma, Harry L.A. Janssen, Scott Fung, Greta Acerbi, Timothy C. Rodell, Paola Fisicaro, Seung Kew Yoon, Adarsh Joshi, Anuj Gaggar, Eric M. Yoshida, Maurizia Rossana Brunetto, Federica Brillo, Marzia Margotti, Giuseppe Pedrazzi, Daniela Cavallone, Carlo Ferrari, Marzia Rossi, Sang Hoon Ahn, Valeria Barili, Carmela Cursaro, Benedetta Massetto, Yang Zhao, Barbara Coco, Pietro Andreone, Diletta Laccabue, G. Mani Subramanian, Rosanna Santoro, Huy N. Trinh, Arianna Alfieri, Jacky Woo, Valeria Piazzolla, Alessandra Mangia
Background & Aims: One strategy to treat chronic hepatitis B virus (HBV) infection could be to increase the functions of virus-specific T cells. We performed a multicenter phase 2 study to evaluate the safety and efficacy of GS-4774, a yeast-based th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1461b67a10cc57cde2f42bfa8f88d730
http://hdl.handle.net/11568/994636
http://hdl.handle.net/11568/994636
Autor:
M. Vitalone, Sheri M. Krams, Kelly Haas, Olivia M. Martinez, Audrey H. Lau, Carlos O. Esquivel, Todd Shawler, William E. Berquist, Ricardo O. Castillo
Publikováno v:
Pediatric Transplantation. 20:1072-1080
Long-term IS in transplant patients has significant morbidity, poorer quality of life, and substantial economic costs. TOL, defined as graft acceptance without functional impairment in the absence of IS, has been achieved in some pediatric LT recipie
Autor:
Liang Wei, Erik Littau, Olivia M. Martinez, M. Vitalone, Sheri M. Krams, Masato Fujiki, Carlos O. Esquivel, Audrey H. Lau
Publikováno v:
Transplantation. 100:781-790
Although the liver is less immunogenic than other solid organs, most liver transplant recipients receive lifelong immunosuppression. In both experimental models and clinical transplantation, total lymphoid irradiation (TLI) has been shown to induce a
Autor:
Henry Lik-Yuen Chan, Wai-Kay Seto, François Habersetzer, John F. Flaherty, Fusao Ikeda, Teresa Santantonio, Hongyuan Wang, Scott Fung, Carol Stanciu, Shrikant Mukewar, Yasuhiro Asahina, Wan-Long Chuang, Anuj Gaggar, Cheng Yuan Peng, Maurizia Rossana Brunetto, D.T. Abdurakhmanov, Fehmi Tabak, Audrey H. Lau, Tetsuro Inokuma, Tuan T. Nguyen, G. Mani Subramanian, Todd T. Brown, Alnoor Ramji, Vithika Suri
Publikováno v:
Clinical Gastroenterology and Hepatology.
Long-term use of tenofovir disoproxil fumarate (TDF) reduces bone mineral density (BMD). Tenofovir alafenamide (TAF), a new prodrug of tenofovir, has shown non-inferior efficacy to TDF in patients with chronic hepatitis B virus (HBV) infection, with