Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Audrey Guérardel"'
Autor:
Emmanuel Somm, Delphine M Vauthay, Audrey Guérardel, Audrey Toulotte, Philippe Cettour-Rose, Philippe Klee, Paolo Meda, Michel L Aubert, Petra S Hüppi, Valérie M Schwitzgebel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50131 (2012)
Poor fetal growth, also known as intrauterine growth restriction (IUGR), is a worldwide health concern. IUGR is commonly associated with both an increased risk in perinatal mortality and a higher prevalence of developing chronic metabolic diseases la
Externí odkaz:
https://doaj.org/article/4cc99019d1ff4164ab33c497a28af848
Autor:
Caroline Poisson, Audrey Guérardel, Jacques Philippe, Mounia Heddad Masson, Yvan Gosmain, Aline Mamin
Publikováno v:
Endocrinology, Vol. 155, No 10 (2014) pp. 3781-3792
Endocrinology
Endocrinology
The Forkhead box A transcription factors are major regulators of glucose homeostasis. They show both distinct and redundant roles during pancreas development and in adult mouse β-cells. In vivo ablation studies have revealed critical implications of
Autor:
Emmanuel Somm, Philippe Klee, Domenico Bosco, Audrey Toulotte, Audrey Guérardel, Pierre Maechler, Valerie M. Schwitzgebel
Publikováno v:
Endocrinology (2016) P. en20152057
Type 1 diabetes (T1DM) results from destruction of most insulin-secreting pancreatic β-cells. The persistence of β-cells decades after the onset of the disease indicates that the resistance of individual cells to the autoimmune insult is heterogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8ddc241928515c9fc571e1c80fbf7e
https://archive-ouverte.unige.ch/unige:89723
https://archive-ouverte.unige.ch/unige:89723
Autor:
Caroline Poisson, Mounia Heddad Masson, Jacques Philippe, Yvan Gosmain, Audrey Guérardel, Claire Cheyssac
Publikováno v:
Endocrinology, Vol. 153, No 9 (2012) pp. 4204-15
The Pax6 transcription factor is crucial for pancreatic α-cells. Indeed, Pax6-deficient mouse models are characterized by markedly altered α-cell differentiation. Our objective was to investigate the role of Pax6 in glucagon secretion process. We u
Autor:
Amar Abderrahmani, Dimitri Favre, Peter Vollenweider, Philippe Froguel, Audrey Guérardel, Nicole Beeler, Saška Brajkovic, Gérard Waeber, Roberto Salvi, Raphael Marenzoni
Publikováno v:
Adipocyte
Adipocyte, vol. 1, no. 3, pp. 157-160
Adipocyte, vol. 1, no. 3, pp. 157-160
Abnormal adipokine production, along with defective uptake and metabolism of glucose within adipocytes, contributes to insulin resistance and altered glucose homeostasis. Recent research has highlighted one of the mechanisms that accounts for impaire
Autor:
Audrey Toulotte, Françoise Rohner-Jeanrenaud, Valerie M. Schwitzgebel, Petra Susan Hüppi, Emmanuel Somm, Christelle Veyrat-Durebex, Audrey Guérardel, Uwe Maskos, Kamel Maouche
Publikováno v:
Molecular Genetics and Metabolism, Vol. 112, No 1 (2014) pp. 64-72
Molecular genetics and metabolism
Molecular Genetics and Metabolism
Molecular Genetics and Metabolism, 2014, 112 (1), pp.64-72. ⟨10.1016/j.ymgme.2014.03.003⟩
Molecular Genetics and Metabolism, Elsevier, 2014, 112 (1), pp.64-72. ⟨10.1016/j.ymgme.2014.03.003⟩
Molecular genetics and metabolism
Molecular Genetics and Metabolism
Molecular Genetics and Metabolism, 2014, 112 (1), pp.64-72. ⟨10.1016/j.ymgme.2014.03.003⟩
Molecular Genetics and Metabolism, Elsevier, 2014, 112 (1), pp.64-72. ⟨10.1016/j.ymgme.2014.03.003⟩
International audience; Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated cation channels well characterized in neuronal signal transmission. Moreover, recent studies have revealed nAChR expression in nonneuronal cell types throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cdc854e43ca0bb1a08f076d30b08f7
https://archive-ouverte.unige.ch/unige:40225
https://archive-ouverte.unige.ch/unige:40225
Autor:
Yvan Gosmain, Karim Bouzakri, Jacques Philippe, Aline Mamin, Claire Cheyssac, Eric Marthinet, Liora S. Katz, Audrey Guérardel
Publikováno v:
Journal of Biological Chemistry, Vol. 285, No 43 (2010) pp. 33381-33393
The paired box homeodomain Pax6 is crucial for endocrine cell development and function and plays an essential role in glucose homeostasis. Indeed, mutations of Pax6 are associated with diabetic phenotype. Importantly, homozygous mutant mice for Pax6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc1aa2d1f763da6da98d5890f83bad9
https://archive-ouverte.unige.ch/unige:20973
https://archive-ouverte.unige.ch/unige:20973
Autor:
Audrey Guérardel, Philippe Froguel, Philippe Amouyel, Nicole Helbecque, Mouna Barat-Houari, Francis Vasseur, Dominique Cottel
Publikováno v:
Molecular Genetics and Metabolism
Molecular Genetics and Metabolism, Elsevier, 2007, 90 (2), pp.199-204. ⟨10.1016/j.ymgme.2006.08.012⟩
Molecular Genetics and Metabolism, Elsevier, 2007, 90 (2), pp.199-204. ⟨10.1016/j.ymgme.2006.08.012⟩
The cocaine and amphetamine regulated transcript (CART), an anorexigenic peptide responding to leptin, is expressed in various areas of the hypothalamus. The role of CART in humans and its potential contribution to abnormalities in feeding control ar
Obesity susceptibility CART gene polymorphism contributes to bone remodeling in postmenopausal women
Publikováno v:
Osteoporosis International
Osteoporosis International, Springer Verlag, 2006, 17 (1), pp.156-7. ⟨10.1007/s00198-005-2022-1⟩
Osteoporosis International, Springer Verlag, 2006, 17 (1), pp.156-7. ⟨10.1007/s00198-005-2022-1⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1b3c39c8ffd4b1052f020a61fa3845
https://hal.archives-ouvertes.fr/hal-00174465
https://hal.archives-ouvertes.fr/hal-00174465
Autor:
Nicole Helbecque, Philippe Froguel, Karine Clément, Delphine Eberlé, Serge Hercberg, Mouna Barat-Houari, Natascha Potoczna, Christopher G. Bell, Vincent Vatin, Philippe Boutin, Christian Dina, Fritz F. Horber, Francis Vasseur, Pilar Galan, Audrey Guérardel, Valérie Vasseur-Delannoy
Publikováno v:
BMC Genetics. 6:19
Cocaine and amphetamine regulated transcript (CART) is an anorectic neuropeptide located principally in hypothalamus. CART has been shown to be involved in control of feeding behavior, but a direct relationship with obesity has not been established.