Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Audrey E. Padula"'
Autor:
Patrick J. Mulholland, Audrey E. Padula, Larry J. Wilhelm, Byung Park, Kathleen A. Grant, Betsy M. Ferguson, Rita Cervera-Juanes
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The underlying genetic and epigenetic mechanisms driving functional adaptations in neuronal excitability and excessive alcohol intake are poorly understood. Small-conductance Ca2+-activated K+ (KCa2 or SK) channels encoded by the KCNN family
Externí odkaz:
https://doaj.org/article/0f5f2a56dec54ef883fca75ec810d00c
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Repeated exposure to ethanol followed by withdrawal leads to the alterations in glutamatergic signaling and impaired synaptic plasticity in the nucleus accumbens (NAc) in both clinical and preclinical models of ethanol exposure. Homer2 is a member of
Externí odkaz:
https://doaj.org/article/1793eab71d0a48789bd4b08b9fd805c1
Autor:
Jennifer A. Rinker, Marcelo F. Lopez, Patrick J. Mulholland, Audrey E. Padula, Howard C. Becker, Robert W. Williams, Megan K. Mulligan
Publikováno v:
Translational Psychiatry
Mood disorders are often comorbid with alcohol use disorder (AUD) and play a considerable role in the development and maintenance of alcohol dependence and relapse. Because of this high comorbidity, it is necessary to determine shared and unique gene
Autor:
Megan K. Mulligan, Marcelo F. Lopez, Robert W. Williams, Fauzan Khan, Audrey E. Padula, Patrick J. Mulholland, Jennifer A. Rinker, Howard C. Becker
Anxiety and mood disorders are often comorbid with alcohol use disorder (AUD) and are considered critical in the development, maintenance, and reinstatement of alcohol dependence and harmful alcohol-seeking behaviors. Because of this high comorbidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99efd6e9b0a94cb18e564cabee999715
Autor:
Marcelo F. Lopez, Patrick J. Mulholland, Reginald Cannady, Tiffany Nguyen, Howard C. Becker, John J. Woodward, Jennifer A. Rinker, Audrey E. Padula
Publikováno v:
Neuropharmacology
Stress is a risk factor that plays a considerable role in the development and maintenance of alcohol (ethanol) abuse and relapse. Preclinical studies examining ethanol-stress interactions have demonstrated elevated ethanol drinking, cognitive deficit
Autor:
William C. Griffin, Patrick J. Mulholland, Natalie S. McGuier, Audrey E. Padula, Elissa J. Chesler, Justin T. Gass
Publikováno v:
Addiction Biology. 21:1097-1112
Alcohol use disorders (AUDs) are a major public health issue and produce enormous societal and economic burdens. Current Food and Drug Administration (FDA)-approved pharmacotherapies for treating AUDs suffer from deleterious side effects and are only
Autor:
Natalie S, McGuier, William C, Griffin, Justin T, Gass, Audrey E, Padula, Elissa J, Chesler, Patrick J, Mulholland
Publikováno v:
Addiction biology. 21(6)
Alcohol use disorders (AUDs) are a major public health issue and produce enormous societal and economic burdens. Current Food and Drug Administration (FDA)-approved pharmacotherapies for treating AUDs suffer from deleterious side effects and are only
Autor:
Audrey E. Padula, Howard C. Becker, Marcelo F. Lopez, Patrick J. Mulholland, Reginald Cannady
Publikováno v:
Alcohol. 60:236
Autor:
Sudarat Nimitvilai, Michael F. Miles, Marcelo F. Lopez, Audrey E. Padula, John J. Woodward, Reginald Cannady, Patrick K. Randall, Natalie S. McGuier, Elissa J. Chesler, Howard C. Becker, Robert W. Williams, Patrick J. Mulholland, William C. Griffin
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 40(8)
Small-conductance Ca(2+)-activated K(+) (KCa2) channels control neuronal excitability and synaptic plasticity, and have been implicated in substance abuse. However, it is unknown if genes that encode KCa2 channels (KCNN1-3) influence alcohol and drug